Results 81 to 90 of about 15,145 (296)

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Perception oro-sensorielle des lipides alimentaires et obésité [PDF]

, 2015
International audienceThe gustation is a dynamic system able to rapid physiological adaptations in response to on-going environmental changes that characterize our feed (rhythm, quality, quantity). Based on the modulation of taste sensitivity thresholds,
Besnard Philippe, Philippe Besnard, Besnard, Philippe   +2 more
core   +1 more source

Libération des acides gras par autolyse enzymatique des triglycérides des graines oléoprotéagineuses

Oléagineux, Corps gras, Lipides, 2001
Les acides gras produits par hydrolyse chimique des lipides des plantes sont des matériaux de base pour l’industrie des biocarburants, des lubrifiants, des plastiques, des détergents et également des adjuvants de préparations commerciales d’herbicides ...
Alibert Gilbert, Mouloungui Zéphirin, Grison René, Romestan Michel   +3 more
doaj   +1 more source

Modulation of the phospholipid transfer protein-mediated transfer of phospholipids by diacylglycerols

Journal of Lipid Research, 2001
Previous studies have shown that diacylglycerols (DAG) are formed during triglyceride hydrolysis in very low density lipoproteins (VLDL), a process that is accompanied by an elevated phospholipid transfer protein (PLTP)-mediated transfer of phopholipids (
Florent Lalanne, Claude Motta, Yan Pafumi, Denis Lairon, Gabriel Ponsin   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Profil Lipoprotéique et Risque Athérogène chez les Drépanocytaires Majeurs au CHU de Cocody

Health Research in Africa
RESUME Introduction. Les formes majeures de drépanocytose sont une source de perturbation des paramètres lipidiques. Cette perturbation est impliquée dans l’apparition de nombreuses maladies cardiovasculaires telles que les accidents vasculaires ...
Vanie BFG, Kouame BGM, Niamke AGG, Koudou CC, Yapo ACB, Lohore KC, Allou AAA   +6 more
doaj   +1 more source

Mise en place des tissus adipeux sous-cutanés et intramusculaires et facteurs de variation quantitatifs et qualitatifs chez le porc

INRAE Productions Animales, 2001
Le choix de la matière première lipidique dans l’alimentation du porc est particulièrement important. Il est bien connu qu’il existe une relation entre la nature des acides gras ingérés et ceux qui vont se déposer dans le tissu adipeux et à un degré ...
J. MOUROT
doaj   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

FEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Cholesteryl ester transfer protein (CETP), HDL capacity of receiving cholesterol and status of inflammatory cytokines in patients with severe heart failure

Lipids in Health and Disease, 2018
Background Heart failure (HF) courses with chronic inflammatory process and alterations in lipid metabolism may aggravate the disease. The aim was to test whether the severity of HF, using brain natriuretic peptide (BNP) as a marker, is associated with ...
Ana Elisa M. Martinelli, Raul C. Maranhão, Priscila O. Carvalho, Fatima R. Freitas, Bruna M. O. Silva, Milena N. C. Curiati, Roberto Kalil Filho, Antonio Carlos Pereira-Barretto   +7 more
doaj   +1 more source