Results 101 to 110 of about 24,383 (256)

Integrated multi‐omics analysis reveals metabolic reprogramming as a key driver of angiotensin II‐induced vascular remodeling

open access: yesVIEW, EarlyView.
This study investigates the molecular alterations underlying angiotensin II (Ang II)‐induced vascular remodeling in cardiovascular diseases using a multi‐omics approach. Through data exploration and integrated multi‐omics analysis, our findings reveal that Ang II‐driven vascular injury in vascular smooth muscle cells is mediated by metabolic ...
Yiwei Hu   +8 more
wiley   +1 more source

Skin Lipid–Microbe Interplay Links Staphylococcus hominis to Barrier Control in Adult Atopic Dermatitis

open access: yesAllergy, EarlyView.
This study investigates mutual interaction of skin microbes and surface lipids in AD using the advanced method of shotgun lipidomics with ultra‐broad coverage of lipids and 16S amplicon sequencing of tape strips taken from lesional and non‐lesional AD and healthy controls.
Madhumita Bhattacharyya   +14 more
wiley   +1 more source

Lipidomics of human umbilical cord serum : identification of unique sterol sulfates [PDF]

open access: yes, 2017
Aim: There are currently limited lipidomics data for human umbilical cord blood. Therefore, the lipidomes of cord sera from six newborns and sera from six nonpregnant females were compared.
Knip, Jan Mikael   +2 more
core   +1 more source

Defective high‐density lipoprotein lipoprotection in type 2 diabetes during acute myocardial infarction is rescued by apolipoprotein M/sphingosine‐1‐phosphate loading

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Mortality of patients with type 2 diabetes (T2D) after acute myocardial infarction (AMI) is tremendous and massively increased compared to non‐T2D individuals. The reasons are unclear. High‐density lipoprotein (HDL) conducts lipoprotection during AMI, leading to improved outcomes.
Jens Vogt   +12 more
wiley   +1 more source

A methodology for elucidating regulatory mechanisms leading to changes in lipid profiles [PDF]

open access: yes, 2017
Introduction It is difficult to elucidate the metabolic and regulatory factors causing lipidome perturbations. Objectives This work simplifies this process.
Barrett, David A.   +3 more
core   +1 more source

A Systematic Review on Applications of Artificial Intelligence for Obesity Prevention

open access: yesObesity Reviews, EarlyView.
ABSTRACT This systematic review examines the applications of artificial intelligence (AI) in preventing obesity, addressing a critical public health issue that affects a substantial portion of the population. With obesity rates rising alarmingly, particularly in the United States, this review synthesizes findings from 46 studies published between 2008 ...
Atefehsadat Haghighathoseini   +4 more
wiley   +1 more source

Plasma metabolomics identifies lipid abnormalities linked to markers of inflammation, microbial translocation, and hepatic function in HIV patients receiving protease inhibitors [PDF]

open access: yes, 2013
Background: Metabolic abnormalities are common in HIV-infected individuals on antiretroviral therapy (ART), but the biochemical details and underlying mechanisms of these disorders have not been defined.
Cassol, Edana   +5 more
core   +1 more source

Natural Variation in TaFAD8‐D Promoter Enhances Thermotolerance in Wheat Through Fatty Acid and Lipid Remodelling

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Heat stress (HS) has become an increasing threat to wheat productivity under global warming. However, the genetic loci for thermotolerance and the underlying molecular mechanisms remain largely unknown. In this study, genetic mapping identified a thermotolerance locus, QMpe.cau‐2D, encoding fatty acid desaturase 8 (FAD8), with the transposable
Hongjian Yu   +15 more
wiley   +1 more source

Hepatitis C virus relies on lipoproteins for its life cycle [PDF]

open access: yes, 2016
Hepatitis C virus (HCV) infects over 150 million people worldwide. In most cases, HCV infection becomes chronic causing liver disease ranging from fibrosis to cirrhosis and hepatocellular carcinoma.
Alonzi, Tonino   +5 more
core   +1 more source

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