Results 111 to 120 of about 24,383 (256)

Plant Lipid Droplets and Derived Lipidic Nano‐Assemblies: Structure, Biogenesis and Pharmaceutical Applications

Plant Biotechnology Journal, EarlyView.
ABSTRACT Lipid droplets (LDs) serve as the primary storage site for neutral lipids in plant cells, with growing evidence supporting many additional biological roles, such as in lipid homeostasis, signalling, trafficking, inflammatory responses and inter‐organelle communication.
Abdulsamie Hanano, Amal Yousfan, Denis J. Murphy   +2 more
wiley   +1 more source

Diet, cancer, and the lipidome. [PDF]

, 2006
International audienceThe potential for dietary fat to interfere with the development of breast cancer by delaying its occurrence makes the identification of defined molecules a mandatory step in cancer prevention.
Bougnoux, Philippe, Couet, Charles, Giraudeau, Bruno   +2 more
core   +2 more sources

Distinct metabolomic and lipidomic profiles in serum samples of patients with primary sclerosing cholangitis

Frontiers in Medicine
IntoductionIdentification of specific metabolome and lipidome profile of patients with primary sclerosing cholangitis (PSC) is crucial for diagnosis, targeted personalized therapy, and more accurate risk stratification.MethodsNuclear magnetic resonance ...
Tanja Fererberger, Christa Buechler, Arne Kandulski, Tanja Elger, Johanna Loibl, Stephan Schmid, Stefanie Sommersberger, Stefan Gunawan, Sebastian Zundler, Sebastian Zundler, Muriel Huss, Dominik Bettenworth, Dominik Bettenworth, Sally Kempa, Simon Weidlich, Bandik Föh, Bandik Föh, Xinyu Huang, Marcin Grzegorzek, Stefanie Derer-Petersen, Ulrich L. Günther, Jens U. Marquardt, Claudia Kunst, Karsten Gülow, Martina Müller, Christian Sina, Christian Sina, Christian Sina, Franziska Schmelter, Hauke C. Tews   +29 more
doaj   +1 more source

Prevention of Atopic Dermatitis in High‐Risk Infants: A Review of the Role of Lipid‐Based Barrier Repair Therapy

Pediatric Dermatology, EarlyView.
ABSTRACT Background/Objective Growing evidence highlights the role of physiological lipids, namely ceramides, cholesterol, and free fatty acids, in maintaining skin barrier function and preventing atopic dermatitis (AD). Current evidence on the efficacy, safety, and clinical relevance of stratum corneum (SC) lipid‐based therapies to prevent AD and ...
Chon‐Wai Jeremy Chan, Marty O. Visscher   +1 more
wiley   +1 more source

Modulation of triglyceride and cholesterol ester synthesis impairs assembly of infectious hepatitis C virus [PDF]

, 2014
In hepatitis C virus infection, replication of the viral genome and virion assembly are linked to cellular metabolic processes. In particular, lipid droplets, which store principally triacylglycerides (TAGs) and cholesterol esters (CEs), have been ...
Hague, Charlotte V., Liefhebber, Jolanda M.P., McLauchlan, John, Wakelam, Michael J.O., Zhang, Qifeng   +4 more
core   +1 more source

Immune Cells as Mediators of Lipidome Influence on Osteoporosis: Evidence from a Mediation Analysis

Diagnostics
Background: Although clinical studies have indicated a possible association between dyslipidemia and osteoporosis, the underlying genetic basis and mechanistic pathways remain insufficiently defined.
Jiheng Xiao, Wei Zhou, Jiatai He, Yanbin Zhu, Yingze Zhang, Liming Xiong   +5 more
doaj   +1 more source

Avocado fruit maturation and ripening: dynamics of aliphatic acetogenins and lipidomic profiles from mesocarp, idioblasts and seed

BMC Plant Biology, 2017
Background Avocado fruit contains aliphatic acetogenins (oft-acetylated, odd-chain fatty alcohols) with promising bioactivities for both medical and food industries. However, we have scarce knowledge about their metabolism.
Carlos Eduardo Rodríguez-López, Carmen Hernández-Brenes, Víctor Treviño, Rocío I. Díaz de la Garza   +3 more
doaj   +1 more source

Longitudinal metabolomics study of phosphate‐adenine‐guanosine‐glucose‐saline‐mannitol stored red blood cells

Transfusion, EarlyView.
Abstract Background The storage of red blood cells (RBCs) is essential for transfusion but leads to storage lesions that compromise RBC quality and increase the risk of transfusion‐related adverse effects, including allergic transfusion reactions (ATRs). Understanding storage‐induced metabolic change is crucial for enhancing transfusion safety.
Gürkan Bal, Maia Dzamashvili, Zhuoran Li, Magda Babina, Nidal Toman, Abdulgabar Salama   +5 more
wiley   +1 more source

Multi-omic Single-Shot Technology for Integrated Proteome and Lipidome Analysis [PDF]

, 2020
Yuchen He, Edrees H. Rashan, Vanessa Linke, Evgenia Shishkova, Alexander S. Hebert, Michael S. Westphall, David J. Pagliarini, Katherine A. Overmyer, Joshua J. Coon   +8 more
openalex   +1 more source

Lactate Dehydrogenase Inhibition Reverts the Fatty Acid‐Induced Neurotoxic Phenotype of Astrocytes

Glia, Volume 74, Issue 3, March 2026.
ALS models display increased LD accumulation. LD accumulation is linked to a neurotoxic phenotype in astrocytes. Lactate dehydrogenase inhibition reverts LD accumulation in ALS astrocytes. ABSTRACT Astrocytes are central to lipid metabolism in the central nervous system.
Daniel Esteve, Mariana Bresque, Daniel Okhuevbie, Sandhya Ramachandran, Mariana Pehar, Marcelo R. Vargas   +5 more
wiley   +1 more source