Results 121 to 130 of about 24,383 (256)
Effects of phospholipase C inhibition on the regulation of membrane lipid metabolism in maize leaves
IntroductionPhospholipase C (PLC) is an enzyme that catalyzes the hydrolysis of glycerophospholipids and can be classified as phospholipase-specific PLC (PI-PLC) and non-specific PLC (NPC) depending on its specific substrate.MethodsIn this study ...
Yulei Wei +9 more
doaj +1 more source
RNA‐Binding Proteins and Ferroptosis in Cancer: Mechanism and Therapeutic Implications
Ferroptosis critically influences cancer cell fate and represents a promising therapeutic strategy. Emerging evidence identifies RNA‐binding proteins (RBPs) as key post‐transcriptional regulators of ferroptosis. The figure summarizes ferroptosis‐related RBPs across cancers: blue RBPs act as tumor suppressors by promoting ferroptosis, whereas red RBPs ...
Linlin Chang +6 more
wiley +1 more source
Metabolomic systems biology of trypanosomes [PDF]
Metabolomics analysis, which aims at the systematic identification and quantification of all metabolites in biological systems, is emerging as a powerful new tool to identify biomarkers of disease, report on cellular responses to environmental ...
BARBARA M. BAKKER +4 more
core +5 more sources
CHANGES OF LIPIDOM IN COLORECTAL CANCER
Colorectal cancer is the second cause of death among all deaths, caused by malignant tumors in the world. Understanding its pathophysiology is important for developing effective strategies for treating this disease.
M. V. Kruchinina +7 more
doaj +1 more source
ABSTRACT Objective We investigated the impact of sex on the subcutaneous adipose tissue (AT) transcriptome and its obesity‐related adaptations. Methods We studied rare BMI‐discordant monozygotic twin pairs (ΔBMI > 2.5 kg/m2; 21 female, 16 male pairs) to assess how sex affects AT and whole‐body metabolism.
Hanna Haltia +12 more
wiley +1 more source
Lipidomic and proteomic analysis revealed large‐scale differences in the midgut composition of the honeybee Apis mellifera and the buff‐tailed bumblebee Bombus terrestris. These differences correlated to increased insecticide absorption in the bumblebee when using an ex vivo Ussing chamber and subsequently in vivo feeding assay (created in Biorender ...
Emmanouil Kokkas +7 more
wiley +1 more source
Bioprospecting of Marine Macrophytes Using MS-Based Lipidomics as a New Approach
The marine environment supports a remarkable diversity of organisms which are a potential source of natural products with biological activities. These organisms include a wide variety of marine plants (from micro- to macrophytes), which have been used in
Elisabete Maciel +5 more
doaj +1 more source
Lipidome profiling of human and equine neutrophil-derived extracellular vesicles and their potential contribution to the ensemble of synovial fluid-derived extracellular vesicles during joint inflammation [PDF]
Laura Varela +8 more
openalex +1 more source

