Results 131 to 140 of about 24,383 (256)
Flexibility of a Eukaryotic Lipidome – Insights from Yeast Lipidomics
PLoS ONE, 2012 Mass spectrometry-based shotgun lipidomics has enabled the quantitative and comprehensive assessment of cellular lipid compositions. The yeast Saccharomyces cerevisiae has proven to be a particularly valuable experimental system for studying lipid-related cellular processes.
Klose, C. +5 more
openaire +5 more sources
Alcohol, Clinical and Experimental Research, Volume 50, Issue 2, February 2026.Using mice, we applied multi‐omics to compare liver and skeletal muscle after chronic alcohol consumption. The liver responded more strongly across genes, proteins, and metabolites, with a lowered PC:PE ratio. Muscle showed inflammation, extracellular matrix activation, impaired mitochondrial energetics, and an elevated PC:PE ratio. Lipidomics affected
Craig R. G. Willis +6 more
wiley +1 more source
Metabolism of polyunsaturated fatty acids in human bone marrow derived mesenchymal stromal cells [PDF]
, 2017 The application of human bone marrow derived mesenchymal stromal cells (hBMSCs) for regenerative or immunomodulatory therapies, e.g. treatment of the graft-versus-host disease, requires in vitro expansion of the cells.
Tigistu-Sahle, Feven
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Acta Physiologica, Volume 242, Issue 2, February 2026.ABSTRACT Aim Acyl‐CoA binding protein plays a vital role in lipid metabolism by mediating the intracellular flux and utilization of long‐chain acyl‐CoAs. We generated an adipocyte‐wide ACBP knockout mouse and a brown adipose tissue‐specific ACBP knockout mouse to investigate ACBP function in adipose tissue.
M. F. Nørremark +13 more
wiley +1 more source
The FASEB Journal, Volume 40, Issue 2, 31 January 2026.A detailed metabolome atlas of the male mouse brain was established, incorporating metabolomic and lipidomic profiling of seven anatomical regions. T2D induced marked metabolic alterations, which were mainly associated with lipotoxicity, defective energy metabolism, proinflammatory processes, and neurotoxicity.
Yang Zhou +5 more
wiley +1 more source
The FASEB Journal, Volume 40, Issue 2, 31 January 2026.Antibiotic‐mediated disruption of commensal microbiota increases corneal cholesterol sulfate (CS) production through upregulation of SULT2B1, resulting in impaired corneal epithelial wound healing. Elevated CS suppresses neutrophil recruitment and epithelial cell migration via inhibition of the DOCK2–Rac pathway.
Mamoru Ogawa +6 more
wiley +1 more source
Obesity dependent metabolic signatures associated with nonalcoholic fatty liver disease progression [PDF]
, 2012 Our understanding of the mechanisms by which nonalcoholic fatty liver disease (NAFLD) progresses from simple steatosis to steatohepatitis (NASH) is still very limited.
Alonso, C +7 more
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T1D-lipidome: Database of lipidomic aberrations during the pathogenesis of type 1 diabetes (T1D)
, 2021 Tommi Suvitaival
openalex +1 more source
245 Level of Colostrum Intake Affects Vaginal Lipidome of Gilts at Three Weeks Postnatal [PDF]
, 2022 Jocelyn V Sheets +3 more
openalex +1 more source