Results 11 to 20 of about 22,082 (266)
Diet, cancer, and the lipidome. [PDF]
Cancer Epidemiology, Biomarkers & Prevention, 2006 International audienceThe potential for dietary fat to interfere with the development of breast cancer by delaying its occurrence makes the identification of defined molecules a mandatory step in cancer prevention.
Bougnoux, Philippe +2 more
core +7 more sources
Understanding the Lipidome at the Systems Level with lipidomeR [PDF]
, 2020 AbstractLipidomics is one of the fastest-growing areas of molecular profiling in medicine. While increasing amounts of lipidomics data are generated, tools for analyzing and interpreting these data are not equally widely available. We present the lipidomeR -- a tool specifically designed for systematic interpretation of large lipidome-wide studies. The
Tommi Suvitaival +1 more
openalex +3 more sources
Analytical and Bioanalytical Chemistry, 2015 Profiling of the individual lipids in biological fluids is of great concern with respect to human health and disease; as a consequence, the task of lipid analysis and profiling has become ever increasingly important, and lipidomics has become the target of postgenomic research.
DONATO, Paola Agata Eustochia +4 more
openaire +4 more sources
Analytical and Bioanalytical Chemistry, 2018 The state-of-art in the lipidomic analysis is summarized here to provide the overview of available sample preparation strategies, mass spectrometry (MS)-based methods for the qualitative analysis of lipids, and the quantitative MS approaches for high-throughput clinical workflows.
Michal Holčapek +2 more
openaire +4 more sources
Lipidomics of Glycosphingolipids [PDF]
Metabolites, 2012 Glycosphingolipids (GSLs) contain one or more sugars that are attached to a sphingolipid moiety, usually to a ceramide, but in rare cases also to a sphingoid base. A large structural heterogeneity results from differences in number, identity, linkage, and anomeric configuration of the carbohydrate residues, and also from structural differences within ...
Farwanah, Hany, Kolter, Thomas
openaire +5 more sources
Epilepsia Open, EarlyView., 2022 Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force established the TASK3 working groups to create common data elements (CDEs) for various preclinical epilepsy research disciplines.
Laura Bindila +11 more
wiley +1 more source
Hepatology, EarlyView., 2022 Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario +12 more
wiley +1 more source
Characterizing the breast cancer lipidome and its interaction with the tissue microbiota
Communications Biology, 2021 Giallourou, Urbaniak et al. investigated the lipidome and microbiome of breast tissues adjacent to breast tumors and control, healthy breast tissue, by examining both bacterial colonization and lipid metabolism.
Natasa Giallourou +5 more
doaj +1 more source
, 2023 Lipids are historically considered a source of energy and a component of cell membranes. Over the last years, many other functions have been studied, and their importance in our health is well established. For this reason, studies on lipidomics have been increasing in the clinical and food science areas.
Machado, Manuela +3 more
openaire +3 more sources
RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease
Hepatology, EarlyView., 2022 RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease. Abstract Background and Aims Receptor‐interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the role of RIPK3 in modulating mitochondria function, coupled with lipid droplet (LD)
Marta B. Afonso +16 more
wiley +1 more source