Results 31 to 40 of about 24,383 (256)

Mycobacterial Lipidomics

open access: yesMicrobiology Spectrum, 2014
ABSTRACTLipidomics is a distinct subspecialty of metabolomics concerned with hydrophobic molecules that organize into membranes. Most of the lipid classes present inMycobacterium tuberculosisare found only inActinobacteriaand show extreme structural diversity. This article highlights the conceptual basis and the practical challenges associated with the
Layre, Emilie   +3 more
openaire   +2 more sources

Animal cell cytokinesis: the role of dynamic changes in the plasma membrane proteome and lipidome [PDF]

open access: yes, 2016
In animal cells, cytokinesis is characterised by the formation of the mitotic spindle that signals the assembly of an actomyosin ring between the spindle poles.
Gould, Gwyn W.
core   +2 more sources

Defining the Baseline and Oxidant Perturbed Lipidomic Profiles of Daphnia magna

open access: yesMetabolites, 2017
Recent technological advancement has enabled the emergence of lipidomics as an important tool for assessing molecular stress, one which has yet to be assessed fully as an approach in an environmental toxicological context.
Nadine S. Taylor   +2 more
doaj   +1 more source

Caloric restriction reveals a metabolomic and lipidomic signature in liver of male mice [PDF]

open access: yes, 2014
Lipid composition, particularly membrane unsaturation, has been proposed as being a lifespan determinant, but it is currently unknown whether caloric restriction (CR), an accepted life-extending intervention, affects cellular lipid profiles.
Jové, Mariona   +6 more
core   +3 more sources

The Impacts of Sortase A and the 4′-Phosphopantetheinyl Transferase Homolog Sfp on Streptococcus mutans Extracellular Membrane Vesicle Biogenesis

open access: yesFrontiers in Microbiology, 2020
Extracellular membrane vesicles (EMVs) are produced by many Gram-positive organisms, but information regarding vesiculogenesis is incomplete. We used single gene deletions to evaluate the impacts on Streptococcus mutans EMV biogenesis of Sortase A (SrtA),
Joyce C. Morales-Aparicio   +8 more
doaj   +1 more source

Free fatty acids support oligodendrocyte survival in a mouse model of amyotrophic lateral sclerosis

open access: yesFrontiers in Cellular Neuroscience, 2023
IntroductionAmyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the white matter degeneration. Although changes in blood lipids are involved in the pathogenesis of neurological diseases, the pathological role of ...
Takashi Maruyama   +6 more
doaj   +1 more source

Utility of mass spectrometry for the diagnosis of the unstable coronary plaque. [PDF]

open access: yes, 2015
Mass spectrometry is a powerful technique that is used to identify unknown compounds, to quantify known materials, and to elucidate the structure and chemical properties of molecules.
Hassan, M, Jacob, SS, Yacoub, MH
core   +1 more source

Associations of the plasma lipidome with mortality in the acute respiratory distress syndrome: a longitudinal cohort study [PDF]

open access: yes, 2018
Background It is unknown if the plasma lipidome is a useful tool for improving our understanding of the acute respiratory distress syndrome (ARDS).
Burant, Charles F   +7 more
core   +2 more sources

Regulation of Light Spectra on Cell Division of the Unicellular Green Alga Haematococcus pluvialis: Insights from Physiological and Lipidomic Analysis

open access: yesCells, 2022
Commercial scale production of natural astaxanthin is currently conducted through cultivation of the green alga Haematococcus pluvialis. This study comprehensively investigated the impact of seven different light spectra on the growth, morphology and ...
Kuo Zhao   +4 more
doaj   +1 more source

Trapped ion mobility spectrometry and PASEF enable in-depth lipidomics from minimal sample amounts

open access: yes, 2020
A comprehensive characterization of the lipidome from limited starting material remains very challenging. Here we report a high-sensitivity lipidomics workflow based on nanoflow liquid chromatography and trapped ion mobility spectrometry (TIMS).
Barsch, A.   +8 more
core   +1 more source

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