Results 31 to 40 of about 22,082 (266)
Caloric restriction reveals a metabolomic and lipidomic signature in liver of male mice [PDF]
Lipid composition, particularly membrane unsaturation, has been proposed as being a lifespan determinant, but it is currently unknown whether caloric restriction (CR), an accepted life-extending intervention, affects cellular lipid profiles.
Jové, Mariona+6 more
core +3 more sources
Toward a Standardized Strategy of Clinical Metabolomics for the Advancement of Precision Medicine [PDF]
Despite the tremendous success, pitfalls have been observed in every step of a clinical metabolomics workflow, which impedes the internal validity of the study.
Kang, Yun Pyo+6 more
core +1 more source
The cellular lipidome comprises over 1000 different lipids. Most lipids look similar having a polar head and hydrophobic tails. Still, cells recognize lipids with exquisite specificity. The functionality of lipids is determined by their local concentration, which varies between organelles, between the two leaflets of the lipid bilayer and even within ...
openaire +4 more sources
To further explore the fructose pro-steatosis mechanism, we performed an integrative analysis of liver transcriptome and lipidome as well as peripheral adipose tissues transcriptome analysis using samples collected from geese overfed with maize flour ...
Rongxue Wei+17 more
doaj +1 more source
Open field study of some Zea mays hybrids, lipid compounds and fumonisins accumulation [PDF]
Lipid molecules are increasingly recognized as signals exchanged by organisms interacting in pathogenic and/or symbiotic ways. Some classes of lipids actively determine the fate of the interactions.
Battilani, Paola+8 more
core +2 more sources
The mainstream of lipidomics involves mass spectrometry-based, systematic, and large-scale studies of the structure, composition, and quantity of lipids in biological systems such as organs, cells, and body fluids. As increasingly more researchers in broad fields are beginning to pay attention to and actively learn about the lipidomic technology, some ...
Jianing Wang, Chunyan Wang, Xianlin Han
openaire +3 more sources
Divergence of Liver Lipidomes in Tibetan and Yorkshire Pigs Living at Different Altitudes
The Tibetan pig is a characteristic breed of the Qinghai-Tibet Plateau with distinct physiological and meat quality attributes. The liver lipid profile can offer an important perspective to explore the uniqueness of Tibetan pigs.
Wei Luo+5 more
doaj +1 more source
Influence of the sebaceous gland density on the stratum corneum lipidome [PDF]
The skin surface lipids (SSL) result from the blending of sebaceous and epidermal lipids, which derive from the sebaceous gland (SG) secretion and the permeability barrier of the stratum corneum (SC), respectively.
Camera, Emanuela+5 more
core +1 more source
Myocardial Lipidomics. Developments in myocardial nuclear lipidomics [PDF]
The development of electrospray ionization mass spectrometry has been critical for the analyses of lipidomes from subcellular organelles. The myocardial nuclear lipidome likely has a key role in the molecular regulation of gene expression. In fact, recent studies have suggested that specific phospholipid classes bind and regulate specific transcription
Carolyn J. Albert+4 more
openaire +3 more sources
A novel methodology for in vivo endoscopic phenotyping of colorectal cancer based on real-time analysis of the mucosal lipidome: a prospective observational study of the iKnife [PDF]
Background: This pilot study assessed the diagnostic accuracy of rapid evaporative ionization mass spectrometry (REIMS) in colorectal cancer (CRC) and colonic adenomas. Methods: Patients undergoing elective surgical resection for CRC were recruited at St.
Alexander, J+17 more
core +1 more source