Results 41 to 50 of about 22,082 (266)

The Impacts of Sortase A and the 4′-Phosphopantetheinyl Transferase Homolog Sfp on Streptococcus mutans Extracellular Membrane Vesicle Biogenesis

Frontiers in Microbiology, 2020
Extracellular membrane vesicles (EMVs) are produced by many Gram-positive organisms, but information regarding vesiculogenesis is incomplete. We used single gene deletions to evaluate the impacts on Streptococcus mutans EMV biogenesis of Sortase A (SrtA),
Joyce C. Morales-Aparicio, Patricia Lara Vasquez, Surabhi Mishra, Ana L. Barrán-Berdón, Manasi Kamat, Kari B. Basso, Zezhang T. Wen, Zezhang T. Wen, L. Jeannine Brady   +8 more
doaj   +1 more source

Crystalline silica-induced proinflammatory eicosanoid storm in novel alveolar macrophage model quelled by docosahexaenoic acid supplementation

Frontiers in Immunology, 2023
IntroductionPhagocytosis of inhaled crystalline silica (cSiO2) particles by tissue-resident alveolar macrophages (AMs) initiates generation of proinflammatory eicosanoids derived from the ω-6 polyunsaturated fatty acid (PUFA) arachidonic acid (ARA) that ...
Olivia K. Favor, Olivia K. Favor, Lichchavi D. Rajasinghe, Lichchavi D. Rajasinghe, Kathryn A. Wierenga, Kathryn A. Wierenga, Krishna R. Maddipati, Kin Sing Stephen Lee, Kin Sing Stephen Lee, Kin Sing Stephen Lee, Andrew J. Olive, James J. Pestka, James J. Pestka, James J. Pestka   +13 more
doaj   +1 more source

Defining the Baseline and Oxidant Perturbed Lipidomic Profiles of Daphnia magna

Metabolites, 2017
Recent technological advancement has enabled the emergence of lipidomics as an important tool for assessing molecular stress, one which has yet to be assessed fully as an approach in an environmental toxicological context.
Nadine S. Taylor, Thomas A. White, Mark R. Viant   +2 more
doaj   +1 more source

Opto-lipidomics of tissues

Advanced Science, 2023
AbstractLipid metabolism and signalling play pivotal functions in biology and disease development. Despite this, there is currently no optical technique available that can directly visualise the lipidome in tissues. In this study, we introduce opto-lipidomics, a new approach to optical molecular tissue imaging.
Magnus Jensen, Shiyue Liu, Elzbieta Stepula, Davide Martella, Anahid A. Birjandi, Keith Farrell‐Dillon, Ka Lung Andrew Chan, Maddy Parsons, Ciro Chiappini, Sarah J. Chapple, Giovanni E. Mann, Tom Vercauteren, Vincenzo Abbate, Mads S. Bergholt   +13 more
openaire   +3 more sources

Comparative lipid profiling dataset of the inflammation-induced optic nerve regeneration. [PDF]

, 2019
In adult mammals, retinal ganglion cells (RGCs) fail to regenerate following damage. As a result, RGCs die after acute injury and in progressive degenerative diseases such as glaucoma; this can lead to permanent vision loss and, eventually, blindness ...
Bhattacharya, Sanjoy K, Caprioli, Joseph, Kwong, Jacky MK, Piqueras, Maria, Stark, David T, Trzeciecka, Anna   +5 more
core   +1 more source

Free fatty acids support oligodendrocyte survival in a mouse model of amyotrophic lateral sclerosis

Frontiers in Cellular Neuroscience, 2023
IntroductionAmyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the white matter degeneration. Although changes in blood lipids are involved in the pathogenesis of neurological diseases, the pathological role of ...
Takashi Maruyama, Takashi Maruyama, Shogo Tanabe, Akiko Uyeda, Tatsunori Suzuki, Tatsunori Suzuki, Rieko Muramatsu   +6 more
doaj   +1 more source

Animal cell cytokinesis: the role of dynamic changes in the plasma membrane proteome and lipidome [PDF]

, 2016
In animal cells, cytokinesis is characterised by the formation of the mitotic spindle that signals the assembly of an actomyosin ring between the spindle poles.
Gould, Gwyn W.
core   +2 more sources

Mycobacterial Lipidomics

Microbiology Spectrum, 2014
ABSTRACTLipidomics is a distinct subspecialty of metabolomics concerned with hydrophobic molecules that organize into membranes. Most of the lipid classes present inMycobacterium tuberculosisare found only inActinobacteriaand show extreme structural diversity. This article highlights the conceptual basis and the practical challenges associated with the
Layre, Emilie, Al-Mubarak, Reem, Belisle, J.T., Moody, D. Branch   +3 more
openaire   +2 more sources

The Effect of Cold Stress on the Root-Specific Lipidome of Two Wheat Varieties with Contrasting Cold Tolerance

Plants, 2022
Complex glycerolipidome analysis of wheat upon low temperature stress has been reported for above-ground tissues only. There are no reports on the effects of cold stress on the root lipidome nor on tissue-specific responses of cold stress wheat roots ...
Bo Eng Cheong, Dingyi Yu, Federico Martinez-Seidel, William Wing Ho Ho, Thusitha W. T. Rupasinghe, Rudy Dolferus, Ute Roessner   +6 more
doaj   +1 more source

Membranes by the Numbers [PDF]

, 2017
Many of the most important processes in cells take place on and across membranes. With the rise of an impressive array of powerful quantitative methods for characterizing these membranes, it is an opportune time to reflect on the structure and function ...
A Finkelstein, A Flamholz, A Nenninger, A Pockels, A Schmidt, A Upadhyaya, AD Dupuy, AE Shyer, AF Bitbol, C Klose, C Klose, C Nielsen, C Tanford, CS Ejsing, D Boal, D Chow, E Evans, E Gorter, E Layre, E Richardson, ES Haswell, FC Neidhardt, FM Hochmuth, G Meer van, GS Manning, GW Li, H Fricke, HC Gaede, HG Garcia, HJ Curtis, I Langmuir, I Vorobyov, J Dai, J Peukes, J Schlessinger, J Song, JB Dacks, JF Nagle, JF Nagle, JF Nagle, JL Sampaio, JT Mika, KC Olbrich, KR Levental, L Bintu, L Fagerberg, L Kalvodova, LK Buehler, M Bialecka-Fornal, M Carvalho, M Kumar, M Li, M Louhivuori, Maya Shamir, MC Field, MK Doeven, MR Alecio, O Kedem, OS Andersen, P Sens, PF Fahey, PG Saffman, R Milo, R Milo, R Phillips, R Phillips, R Phillips, RW Robinett, S Mahajan, S Ramadurai, S Takamori, T Hanai, T Savin, TA Harroun, U Seifert, Uri Moran, W Almers, W Bialek, W Rawicz, Walter Neupert, WD Stein, Y Gambin, Y Shibata, Y Shibata   +83 more
core   +2 more sources