Results 51 to 60 of about 24,383 (256)

Cross-Platform Comparison of Untargeted and Targeted Lipidomics Approaches on Aging Mouse Plasma. [PDF]

, 2018
Lipidomics - the global assessment of lipids - can be performed using a variety of mass spectrometry (MS)-based approaches. However, choosing the optimal approach in terms of lipid coverage, robustness and throughput can be a challenging task.
Brunet, Anne, Contrepois, Kévin, Hornburg, Daniel, Mahmoudi, Salah, Papsdorf, Katharina, Snyder, Michael, Ubhi, Baljit K   +6 more
core   +3 more sources

Integrative analysis of transcriptome and lipidome reveals fructose pro-steatosis mechanism in goose fatty liver

Frontiers in Nutrition, 2023
To further explore the fructose pro-steatosis mechanism, we performed an integrative analysis of liver transcriptome and lipidome as well as peripheral adipose tissues transcriptome analysis using samples collected from geese overfed with maize flour ...
Rongxue Wei, Rongxue Wei, Chunchun Han, Chunchun Han, Shouhai Wei, Shouhai Wei, Yongqiang Teng, Yongqiang Teng, Liang Li, Liang Li, Hehe Liu, Hehe Liu, Shengqiang Hu, Shengqiang Hu, Bo Kang, Bo Kang, Hengyong Xu, Hengyong Xu   +17 more
doaj   +1 more source

Lipidomic Profiling of Saccharomyces cerevisiae and Zygosaccharomyces bailii Reveals Critical Changes in Lipid Composition in Response to Acetic Acid Stress [PDF]

, 2013
When using microorganisms as cell factories in the production of bio-based fuels or chemicals from lignocellulosic hydrolysate, inhibitory concentrations of acetic acid, released from the biomass, reduce the production rate.
Bettiga, Maurizio, Lindberg, Lina, Olsson, Lisbeth, Riezman, Howard, Santos, Aline XS   +4 more
core   +4 more sources

Advances in lipidomics [PDF]

Clinica Chimica Acta, 2020
The present article examines recently published literature on lipids, mainly focusing on research involving glycero-, glycerophospho- and sphingo-lipids. The primary aim is identification of distinct profiles in biologic lipidomic systems by ultra-high-performance liquid chromatography (UHPLC) coupled with mass spectrometry (MS, tandem MS) with ...
Henri F. Avela, Heli Sirén
openaire   +2 more sources

Mouse mitochondrial lipid composition is defined by age in brain and muscle [PDF]

, 2017
Functionality of the lipid rich mitochondrial organelle declines with increased age. Recent advances in lipidomic technologies allowed us to perform a global characterisation of lipid composition in two different tissue types and age ranges.
Al-Gubory, Arnould, Becker, Brügger, Chakrabarti, Chakrabarti, Cherkaoui-Malki, Coleman, Corcelli, Daum, Eckert, Goto, Gottlieb, Ha, Han, Harman, Hulbert, Klein-Seetharaman, Koehler, Koltai, Kristal, Lavialle, Liu, Liu, Madeo, McQuibban, Moreau, Nakaya, Nicolaou, Nunnari, Osiewacz, Patel, Pufa, Rea, Rudich, Schägger, Sonninen, Tasseva, Vaz, Verkhratsky, Vidal-Puig, Wenk   +41 more
core   +1 more source

Subcellular organelle lipidomics in TLR-4-activated macrophages1[S]

Journal of Lipid Research, 2010
Lipids orchestrate biological processes by acting remotely as signaling molecules or locally as membrane components that modulate protein function. Detailed insight into lipid function requires knowledge of the subcellular localization of individual ...
Alexander Y. Andreyev, Eoin Fahy, Ziqiang Guan, Samuel Kelly, Xiang Li, Jeffrey G. McDonald, Stephen Milne, David Myers, Hyejung Park, Andrea Ryan, Bonne M. Thompson, Elaine Wang, Yihua Zhao, H. Alex Brown, Alfred H. Merrill, Christian R.H. Raetz, David W. Russell, Shankar Subramaniam, Edward A. Dennis   +18 more
doaj   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Holistic lipidomics of the human gut phenotype using validated ultra-high-performance liquid chromatography coupled to hybrid orbitrap mass spectrometry [PDF]

, 2017
As lipids are assigned a plethora of biological functions, it is evident that dysregulated lipid metabolism signifies a key element in many pathological conditions. With this rationale, this study presents a validated lipidomics platform to map the fecal
Bos, Simon, De Paepe, Ellen, Lapauw, Bruno, Pomian, Beata, Van Meulebroek, Lieven, Vanhaecke, Lynn, Vercruysse, Vicky   +6 more
core   +3 more sources

Toward a Standardized Strategy of Clinical Metabolomics for the Advancement of Precision Medicine [PDF]

, 2020
Despite the tremendous success, pitfalls have been observed in every step of a clinical metabolomics workflow, which impedes the internal validity of the study.
Kang, Yun Pyo, Kim, Hyung Min, Kwon, Sung Won, NGHI, TRAN, Nguyen Hoang Anh, Nguyen Phuoc Long, PARK, SANG KI   +6 more
core   +1 more source

Exploring the mediating role of the plasma lipidome in the pathway from the gut microbiota to dementia: a Mendelian randomization study

Archives of Medical Science
Introduction Previous studies have indicated a potential association between the gut microbiota (GM) and dementia; however, the exact cause-and-effect relationships between GM, various types of dementia, and the potential influence of the plasma lipidome
Binghan Li, Xu Sun, Xiao Luo, Yuting Kan, Weisen Wang, Tianren Wang, Cheng Wu, Yongbo Hu, Xiaoying Bi   +8 more
doaj   +1 more source