Results 71 to 80 of about 24,383 (256)

UPLC-Q-Exactive Orbitrap-MS-Based Untargeted Lipidomic Analysis of Lipid Molecular Species in Spinal Cords from Different Domesticated Animals

Foods, 2023
Lipids are crucial components for the maintenance oof normal structure and function in the nervous system. Elucidating the diversity of lipids in spinal cords may contribute to our understanding of neurodevelopment.
Na Li, Long Xu, Hongbo Li, Zhenbin Liu, Haizhen Mo, Yue Wu   +5 more
doaj   +1 more source

Pirin Transcriptionally Regulates PLA2G4A To Inhibit Ferroptosis in Colorectal Cancer via Lipid Profile Remodeling

Advanced Science, EarlyView.
This study identifies Pirin (PIR), an iron‐binding protein, as a critical ferroptosis suppressor in colorectal cancer through lipid membrane remodeling. PIR, induced by NRF2 during ferroptotic stress, transcriptionally regulates PLA2G4A to shift cellular lipid composition away from ferroptosis‐permissive polyunsaturated phospholipids.
Wei Shi, Yue Qi Ong, Prativa Majee, Esther SM Wong, Amhed Missael Vargas Velazquez, Kerem Fidan, Pierce Kah‐Hoe Chow, Wai Leong Tam, Ker Kan Tan, Iain Beehuat Tan, Vinay Tergaonkar   +10 more
wiley   +1 more source

Serum Metabolome and Lipidome Changes in Adult Patients with Primary Dengue Infection [PDF]

, 2013
10.1371/journal.pntd.0002373PLoS Neglected Tropical ...
A Mangerich, A Mathew, A Sreekumar, A Zuniga, AL St John, B Brugger, BR Murphy, C Lu, C Rothwell, CF Nathan, Choon Nam Ong, CN Serhan, CN Serhan, DJ Gubler, DJ Gubler, DL Diamond, DP Ng, E Avota, E Sandalova, E Zaitseva, E Zigmond, EC Laiakis, EG Bligh, EL Azeredo, Eng Eong Ooi, F Facciotti, Fengguo Xu, G Birungi, G Hasko, GF Nixon, J Chen, J Guarner, J Herz, J Mattner, J Xia, JC Suvarna, JG Low, JG Low, JH Yang, JK Nicholson, K Izawa, K Jessie, K Myo, Kun Lu, L Gil, Liang Cui, MC Ruzek, ME Miller, MG Guzman, N Vinayavekhin, NS Heaton, P Klassen, PC Calder, PC Neves-Souza, PG Hellewell, PJ Brennan, R Al-Mubarak, R Takhampunya, RA Lewis, RC Seet, RL Shaner, RW Wannemacher Jr, S Noisakran, SB Halstead, Scott F. Michael, SJ Gagnon, SL Tilley, Steven R. Tannenbaum, T Akaike, T Kawano, T Pluskal, TJ Nevalainen, W Shi, WW Goh, X Han, Y Kumar, YA Hannun, Yadunanda Kumar, Yie Hou Lee, Z Wang   +79 more
core   +4 more sources

White matter lipidome alterations in the schizophrenia brain

Schizophrenia
Numerous brain imaging studies have reported white matter alterations in schizophrenia, but the lipidome analysis of the corresponding tissue remains incomplete.
Dmitry Senko, Olga Efimova, Maria Osetrova, Nikolay Anikanov, Maria Boyko, Maksim Sharaev, Anna Morozova, Yana Zorkina, Maksim Kislov, Georgiy Kostyuk, Elena Stekolshchikova, Philipp Khaitovich   +11 more
doaj   +1 more source

A Lipidomic Analysis of Leaves of Esca-Affected Grapevine Suggests a Role for Galactolipids in the Defense Response and Appearance of Foliar Symptoms

Biology, 2020
Both qualitative and quantitative changes occur in the lipid composition of Vitis vinifera L. tissues, which may compromise the defense response against Esca complex disease, a widespread and damaging trunk disease. In this study, a lipidomic analysis of
Piebiep Goufo, Isabel Cortez
doaj   +1 more source

Tutorial on lipidomics [PDF]

Analytica Chimica Acta, 2019
The mainstream of lipidomics involves mass spectrometry-based, systematic, and large-scale studies of the structure, composition, and quantity of lipids in biological systems such as organs, cells, and body fluids. As increasingly more researchers in broad fields are beginning to pay attention to and actively learn about the lipidomic technology, some ...
Jianing Wang, Chunyan Wang, Xianlin Han
openaire   +2 more sources

Fasting and Refeeding Mediated Phospholipid Remodeling Plays an Important Role in Improving Meat Quality of Aged Laying Hens

Animal Research and One Health, EarlyView.
ABSTRACT This study explored fasting‐induced physiological remodeling effects on meat quality in aged laying hens. Fasting for 15 days (F15) significantly reduced abdominal fat, intermuscular fat width, subcutaneous fat thickness, and liver index versus pre‐fasting (F0) (p < 0.05), which recovered post‐refeeding.
Xiaoran Zhang, Jun Zhang, Yadong Tian, Donghua Li, Yanhua Zhang, Lujie Zhang, Yujie Gong, Xiangtao Kang, Ruirui Jiang   +8 more
wiley   +1 more source

Membranes by the Numbers [PDF]

, 2017
Many of the most important processes in cells take place on and across membranes. With the rise of an impressive array of powerful quantitative methods for characterizing these membranes, it is an opportune time to reflect on the structure and function ...
A Finkelstein, A Flamholz, A Nenninger, A Pockels, A Schmidt, A Upadhyaya, AD Dupuy, AE Shyer, AF Bitbol, C Klose, C Klose, C Nielsen, C Tanford, CS Ejsing, D Boal, D Chow, E Evans, E Gorter, E Layre, E Richardson, ES Haswell, FC Neidhardt, FM Hochmuth, G Meer van, GS Manning, GW Li, H Fricke, HC Gaede, HG Garcia, HJ Curtis, I Langmuir, I Vorobyov, J Dai, J Peukes, J Schlessinger, J Song, JB Dacks, JF Nagle, JF Nagle, JF Nagle, JL Sampaio, JT Mika, KC Olbrich, KR Levental, L Bintu, L Fagerberg, L Kalvodova, LK Buehler, M Bialecka-Fornal, M Carvalho, M Kumar, M Li, M Louhivuori, Maya Shamir, MC Field, MK Doeven, MR Alecio, O Kedem, OS Andersen, P Sens, PF Fahey, PG Saffman, R Milo, R Milo, R Phillips, R Phillips, R Phillips, RW Robinett, S Mahajan, S Ramadurai, S Takamori, T Hanai, T Savin, TA Harroun, U Seifert, Uri Moran, W Almers, W Bialek, W Rawicz, Walter Neupert, WD Stein, Y Gambin, Y Shibata, Y Shibata   +83 more
core   +2 more sources

Comprehensive Metabolomics Identified the Prominent Role of Glycerophospholipid Metabolism in Coronary Artery Disease Progression

Frontiers in Molecular Biosciences, 2021
Background: Coronary stenosis severity determines ischemic symptoms and adverse outcomes. The metabolomic analysis of human fluids can provide an insight into the pathogenesis of complex disease.
Hui Chen, Hui Chen, Hui Chen, Zixian Wang, Zixian Wang, Zixian Wang, Zixian Wang, Min Qin, Min Qin, Min Qin, Bin Zhang, Bin Zhang, Lu Lin, Qilin Ma, Chen Liu, Xiaoping Chen, Hanping Li, Weihua Lai, Shilong Zhong, Shilong Zhong, Shilong Zhong, Shilong Zhong   +21 more
doaj   +1 more source

Untargeted Metabolomics Identifies N‐Lactoyl‐Amino Acids as Dose‐Responsive Plasma Biomarkers of Metformin Adherence in Type 2 Diabetes

Clinical Pharmacology &Therapeutics, EarlyView.
Metformin is the most widely prescribed antidiabetic drug, yet adherence remains difficult to objectively assess. Using untargeted metabolomics and lipidomics, we analyzed plasma from 637 patients with type 2 diabetes (T2D) with confirmed metformin use and 143 nondiabetic controls, annotating 614 metabolites.
Tomas Cajka, Jiri Hricko, Lucie Rudl Kulhava, Michaela Paucova, Michaela Novakova, Veronika Hola, Stanislava Rakusanova, Oliver Fiehn, Vojtech Skop, Ivana Lankova, Iva Miskova, Terezie Pelikanova, Martin Haluzik   +12 more
wiley   +1 more source