Results 121 to 130 of about 34,809 (298)

Study design and workflow for the lipidomic analyses.

, 2014
Heterozygous female fat-1 and WT mice were fed a 6-month-long diet containing 10% corn oil, which is particularly enriched in omega-6 PUFAs. Blood was collected and plasma samples were prepared and divided into two aliquots.
Andrew Baker (555033), James Murphy (555034), Katrin Strassburg (555031), Angela Doneanu (555032), Jay Johnson (5658730), James Langridge (555035), Giuseppe Astarita (194314), Jing X. Kang (125506), Rob J. Vreeken (421023), Bin Wang (30851), Jennifer H. McKenzie (166457), Thomas Hankemeier (135670)   +11 more
core   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

Identification and validation of a blood- based diagnostic lipidomic signature of pediatric inflammatory bowel disease [PDF]

Improved biomarkers are needed for pediatric inflammatory bowel disease. Here we identify a diagnostic lipidomic signature for pediatric inflammatory bowel disease by analyzing blood samples from a discovery cohort of incident treatment-naïve pediatric ...
Salihovic, Samira, Kruse, Robert, Hedin, Charlotte R. H.,, Nystrom, Niklas,, Olbjørn, Christine, Oresic, Matej,, Carlson, Marie, Wewer, Vibeke,, Olbjorn, Christine,, Keita, Åsa,, Keita, Asa V.,, Noble, Alexandra J., Hedin, Charlotte R. H., Bazov, Igor, Bazov, Igor,, Soderholm, Johan D.,, Nyström, Niklas, Magnusson, Maria K.,, Mathisen, Charlotte Bache-Wiig, Andersen, Svend, Satsangi, Jack, Öhman, Lena, Hyotylainen, Tuulia, Hyotylainen, Tuulia,, Halfvarson, Jonas, Dorn-Rasmussen, Maria, Dorn-Rasmussen, Maria,, Burisch, Johan, Hoivik, Marte Lie, Uhlig, Holm H.,, D'Amato, Mauro, Salihovic, Samira,, Söderholm, Johan D., Noble, Alexandra J.,, Huppertz-Hauss, Gert,, Söderholm, Johan D,, Satsangi, Jack,, Lindqvist, Carl Marten,, Perminow, Gøri, Lindqvist, Carl Mårten, Olbjorn, Christine, Magnusson, Maria K., Mathisen, Charlotte Bache-Wiig,, Carlson, Marie,, Andersen, Svend,, Wewer, Vibeke, Huppertz-Hauss, Gert, Perminow, Gori,, Burisch, Johan,, D’Amato, Mauro, Detlie, Trond Espen,, Opheim, Randi,, Hoivik, Marte Lie,, Repsilber, Dirk,, Halfvarson, Jonas,, Kruse, Robert,, D'Amato, Mauro,, Detlie, Trond Espen, Ohman, Lena,, Uhlig, Holm H., Repsilber, Dirk, Perminow, Gori, Opheim, Randi, Keita, Åsa V., Orešič, Matej   +64 more
core   +1 more source

A bioinspired catalytic nanoplatform for ferroptosis‐immunotherapy synergy in metastatic cancer

BMEMat, EarlyView.
The bioinspired nanoplatform MnMSN@MnP‐PEG co‐delivers manganese peroxidase and manganese ions to synergistically induce immunogenic ferroptosis and activate the cGAS‐STING pathway, eliciting potent antitumor immunity against primary and metastatic tumors.
Panpan Xue, Hai Cai, Ying Sun, Yaxin Ma, Siyuan Liu, Jinying Zhu, Yan Chen, Xuemei Zeng, Shuangqian Yan   +8 more
wiley   +1 more source

Supplementary Material for: Gestational Age and the Cord Blood Lipidomic Profile in Late Preterm and Term Infants

, 2018
Background: Lipid metabolism is vital to fetal development and cardiometabolic health and the final weeks of gestation are known to be a time of intense metabolic activity.
McCloskey K. (5428130), Vuillermin P. (5428118), Weir J.M. (5428121), Ponsonby A.-L. (5428124), Carlin J.B. (4137019), Blangero J. (4139974), Burgner D. (5428100), Jayawardana K. (5428112), Curran J.E. (4139980), BIS investigator group (5428109), Meikle P.J. (5428115), De Livera A.M. (5428106), Mellett N.A. (5428103), Collier F. (5428127)   +13 more
core   +1 more source

Membrane lipid metabolism as a regulatory frontier in neural crest biology: Roles for sphingolipids, cholesterol, and lipid rafts

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are multipotent, migratory stem‐like cells essential for vertebrate development that contribute broadly to many tissues including the craniofacial skeleton, peripheral nervous system, and pigment‐producing cells. Their development progresses through phases of induction, specification, delamination, migration, and ...
Allison E. Mancini, Mallorie P. Jenne, Michael L. Piacentino   +2 more
wiley   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza, Greta Volpedo, Antonella Riva, Pasquale Striano, Annamaria Vezzani   +4 more
wiley   +1 more source

Editorial: Advances in the research of diabetic nephropathy

Frontiers in Endocrinology, 2023
Mohamed Abu-Farha, Katsumi Iizuka, Daisuke Yabe, Fahd Al-Mulla, Jehad Abubaker   +4 more
doaj   +1 more source

Efficacy, Tolerability, and Face Lipidomic Modification of New Regimen with Cleanser and Corrective Serum in Women with Acne-Prone Skin

Applied Sciences
Acne-prone skin is a common condition in adult women, and skin imperfections could affect quality of life and self-esteem. This study aimed to investigate the efficacy of a cosmetic combination regimen for face care (a cleanser gel and a serum containing
Maria Vitale, María José Gómez-Sánchez, Mencía Hermosa Vicente, Francesca Colombo, Massimo Milani   +4 more
doaj   +1 more source