Results 101 to 110 of about 34,809 (298)

Lipidomics [PDF]

Analytical Chemistry, 2014
Richard W, Gross, Michal, Holčapek
openaire   +2 more sources

LipidON: A reference lipidomic dataset of the mouse optic nerve

To address this gap, we present LipidON (a reference lipidomic dataset of the mouse optic nerve), the first manually curated lipidomic resource focused on the mouse optic nerve under normal physiological conditions.
García-Cañas, Virginia, Simó, Carolina, Mamani-Huanca, Maricruz, García-Martín, Gonzalo, Lorenzo, M. Paz, Cubelos, Beatriz   +5 more
core   +1 more source

GSTM4 Suppresses Prostate Cancer Progression by Targeting TRIM27‐mediated ACLY Ubiquitination and Lipid Metabolism

Advanced Science, EarlyView.
GSTM4 enhances the interaction between ACLY and the E3 ubiquitin ligase TRIM27, thereby increasing K48‐linked ubiquitination at the K554 site of ACLY and promoting its degradation. Consequently, GSTM4 regulates lipid synthesis, as well as the proliferation and metastasis of PCa cells, by modulating ACLY stability.
Kang‐Ping Xiong, Fei Liu, Wang Wang, Gang Wang, Kai‐Yu Qian, Sheng Tu, Si‐Ming Chen, Hui‐Min Xu, Shan‐Shan Zhang, Yong Li, Xing‐Huan Wang, Hong Weng   +11 more
wiley   +1 more source

Clinical symptom improvement and lipidomic signatures in overweight/obese PCOS treated by lifestyle and acupuncture intervention

Frontiers in Medicine
BackgroundPolycystic ovary syndrome (PCOS) is interrelated with obesity. Lifestyle intervention, mainly focusing on weight loss, has emerged as promising strategies to improve fertility outcomes in women with obesity.
Haolin Zhang, Haolin Zhang, Wenmin Tian, Dong Li, Dong Li, Yang Chen, Yang Ye, Yang Ye, Zejun Huo, Zejun Huo, Li Shi, Ii Fukuzawa, Ii Fukuzawa, Shuhan Yang, Shuhan Yang, Yang Yang, Yang Yang, Hua Zhang, Lin Zeng, Xiyan Xin, Xiyan Xin, Chunyong Wang, Wen Ma, Weiyu Qiu, Zhihui Qi, Heng Dai, Na Li, Haining Wang, Rong Li, Rong Li   +29 more
doaj   +1 more source

ACSL4‐Dependent Lysosomal Lipid Peroxidation Links WTAP‐Mediated m6A Modification to Intervertebral Disc Degeneration

Advanced Science, EarlyView.
IL‐1β upregulates the protein level of WTAP, which promotes the m6A modification of ACSL4 mRNA in an IGF2BP2‐dependent manner, thereby enhancing its stability. The increased ACSL4 drives lipid peroxidation, leading to lysosomal membrane permeabilization (LMP) and impaired mitophagy, which collectively accelerate intervertebral disc degeneration (IVDD).
Shu Jia, Xu Gao, Laimin Zhu, Haixia Song, Jing Wu, Shang Chen, Sheng Gao, Lu Zhang, Chunyang Meng   +8 more
wiley   +1 more source

Lyssavirus Nucleoprotein Induces GPAT4‐Mediated CYB5R1 Depalmitoylation to Suppress Ferroptosis and Promote Viral Replication

Advanced Science, EarlyView.
Lipid metabolism plays a vital role in viral infections. Here, we reveal that the lyssavirus N protein regulates GPAT4 to induce lipid droplet biogenesis, restricting CYB5R1 palmitoylation and reducing ferroptosis susceptibility to ultimately promote viral replication.
Jianqing Zhao, Chuan Liang, Pingping Chen, Meixin Sun, Zhen F. Fu, Ling Zhao, Ming Zhou   +6 more
wiley   +1 more source

Biochemical Characterization of Lipids, Proteins, and Polysaccharides from the Marine Diatom Phaeodactylum tricornutum Cultivated in Pilot-Scale Photobioreactors

Molecules
Phaeodactylum tricornutum was cultivated in a 1000 L photobioreactors using f/2 medium. The resulting algal biomass contained 24.5% lipids, 37.8% protein, 19.4% carbohydrates, and had a gross energy content of 19.8 MJ/kg.
Arjun H. Banskota, Joseph P. M. Hui, Kaitlyn Blatt-Janmaat, Roumiana Stefanova, Alysson Jones, Sean M. Tibbetts, Patrick J. McGinn   +6 more
doaj   +1 more source

The Non-Targeted Lipidomic-Based Classifier Reveals Two Candidate Biomarkers for Ischemic Stroke in Hypertensive Individuals [PDF]

Wenbin Wang,1 Lin Liu,2 Weida Qiu,1 Chaolei Chen,1 Yuqing Huang,1 Anping Cai,1 Zhiqiang Nie,1 Yanqiu Ou,1 Yicheng Zhu,1 Yingqing Feng1 1Department of Cardiology, Hypertension Research Laboratory, Guangdong Cardiovascular Institute, Guangdong Provincial ...
Cai A, Qiu W, Liu L, Huang Y, Zhu Y, Feng Y, Nie Z, Wang W, Ou Y, Chen C   +9 more
core  

Raw Lipidomic data ser DIO mice

Raw lipidomic data set (serum and fecal samples) from DIO mice treated with and without KHKi under a HFHS diet.
Carolina Echeverria (24369449), Marcus D. Goncalves (10431839)   +1 more
core   +1 more source

Spatially Informed Feature Selection and Machine Learning in Matrix‐Assisted Laser Desorption/Ionization Imaging for Cohort‐Scale Molecular Tissue Phenomics in Glioblastoma

Advanced Intelligent Discovery, EarlyView.
Matrix‐assisted laser desorption/ionization imaging‐based identification of reliable small molecule markers across heterogeneous glioblastoma cohorts is challenging with intensity‐only methods. We present spatially informed feature selection (SIFS), a spatially informed framework that prioritizes molecules consistently colocalizing with histopathology.
Shad A. Mohammed, Denis Abu Sammour, Dirk C. Hoffmann, Philipp Sievers, Tobias Bausbacher, Melissa Hahn, Yasemin Ucal, Iris Mildenberger, Christiane A. Opitz, Stefan Schmidt, Michael Platten, Oliver Wasenmüller, Wolfgang Wick, Andreas von Deimling, Tobias Kessler, Carsten Hopf   +15 more
wiley   +1 more source