Results 81 to 90 of about 36,600 (265)

An Integrated Artificial Intelligence Framework for Nanomedicine Engineering

Advanced Science, EarlyView.
This review outlines a closed‐loop AI ecosystem for nanomedicine engineering. By synergizing multimodal data harmonization, objective‐driven AI architectures, and automated high‐throughput validation, this “Design‐Make‐Test‐Analyze” (DMTA) workflow transforms traditional heuristic formulation into a predictive, self‐optimizing paradigm, accelerating ...
Meichen Dong, Qin Luo, Xinyi Ding, Chaoqi Lu, Ru Zhang, Qingqing Tan, Zhiqing Pang, Defang Ouyang, Dongsheng Li, Jiaxuan Xia, Jianxin Wang   +10 more
wiley   +1 more source

Gastroesophageal Reflux Aspiration in the Post Lung Transplant Patient: a Targeted Bile Acid Metabolomic and Lipidomic Approach.

, 2015
Gastroesophageal Reflux Aspiration in the Post Lung Transplant Patient: a Targeted Bile Acid Metabolomic and Lipidomic ...
Kim C, Shah L, Cremens S, Naroji S, Sonett J, Lederer D, Aramini B, Zhou B, Gilbert DP, D'Ovidio F, Raza K, Arcasoy S, Chan R, Robbins H   +13 more
core  

Nuciferine Suppresses Inflammatory Hepatocarcinogenesis by Targeting cPLA2‐Dependent Arachidonic Acid Metabolism

Advanced Science, EarlyView.
Nuciferine directly binds the C2 domain of cPLA2, impairing its Ca2+‐dependent membrane translocation and activation. By suppressing arachidonic acid release and downstream pro‐inflammatory eicosanoid production, nuciferine attenuates NF‐κB signaling and inflammatory hepatocarcinogenesis, revealing cPLA2 as a direct molecular target underlying its ...
Jing Sun, Xinyan Wu, Shuwei Luo, Yilang Liu, Jie Liu, Jun Lu, Weimin Wang, Xiao Feng, Tuo Zhang, Dipak Panigrahy, Jianjun Deng, Xiaojun Liao, Haixia Yang   +12 more
wiley   +1 more source

Overall statistical analysis of anthropometric, transcriptomic and lipidomic data.

, 2019
Panel A: Principal component analysis (PCA) of all anthropometric, transcriptomic and lipidomic data. All anthropometric, plasma, transcriptomic and lipidomic data was assembled into an Excel spreadsheet for mice in the 3 groups (RD46, WD38 and WD46 ...
Melinda H. Spooner (6551933), Weijian Zhang (446407), Manuel Garcia-Jaramillo (6551930), Donald B. Jump (498480), Christiane V. Löhr (418937), Carmen P. Wong (512550)   +5 more
core   +1 more source

Semi‐Artificial Photosynthesis Enables Light‐Driven Biomanufacturing in Non‐Photosynthetic Bacteria

Advanced Science, EarlyView.
A non‐invasive strategy exploits endogenous H2S metabolism in B. subtilis to drive in situ CdS biomineralization, enabling tight bio‐abiotic contact without genetic modification. Light harvested by the biomineralized nanoparticles powers NADPH regeneration, elevating 2’‐fucosyllactose and surfactin titres two‐ to three‐fold.
Jie Zheng, Anqi Tong, Wenxin Li, Meng Qiao, Yang Gu, Muhammad Sohail, Shan He, Sheng Yang, Xing Zhang   +8 more
wiley   +1 more source

EARLY LIFE INFECTION IS ASSOCIATED WITH PROINFLAMMATORY, ATHEROGENIC, AND DIABETOGENIC METABOLOMIC AND LIPIDOMIC PROFILES AT 12 MONTHS OF AGE

, 2022
EARLY LIFE INFECTION IS ASSOCIATED WITH PROINFLAMMATORY, ATHEROGENIC, AND DIABETOGENIC METABOLOMIC AND LIPIDOMIC PROFILES AT 12 MONTHS OF ...
S Ranganathan (13309257), P Sly (13371066), Martin O'Hely (13088148), R Saffery (842916), T Mansell (10708035), A Smith (7678280), P Vuillermin (13411944), D Burgner (13309263), P Meikle (13347036), S Bekkering (13323933), F Collier (9893246), M Tang (5107769), A-L Ponsonby (13627312), R Rowland (9894569), S Burugupalli (13347033)   +14 more
core   +1 more source

Evaluation of Lipid Quality in Fruit: Utilizing Lipidomic Approaches for Assessing the Impact of Biotic Stress on Pecans (Carya illinoinensis)

Foods
There is a scarcity of data on how the lipid composition of oily seeds changes in response to biotic stress. Yellow peach moth (Conogethes punctiferalis) has caused massive economic losses on the pecan (Carya illinoinensis) industry.
Lingyuan Zhou, Wei Zhang, Qingyang Li, Maokai Cui, Danyu Shen, Jinping Shu, Runhong Mo, Yihua Liu   +7 more
doaj   +1 more source

HADHA K406 Lactylation Regulates Metabolic Reprogramming and Suppresses Immune Responses in Gastric Cancer

Advanced Science, EarlyView.
HADHA K406 lactylation fuels fatty acid β‐oxidation and HMGCR‐dependent cholesterol biosynthesis, fostering immunosuppressive MDSCs and exhausted CD8+ T cells in gastric cancer. Loss of this modification blocks cholesterol production, remodels the tumor microenvironment, and tumor growth is suppressed via combined inhibition of HMGCR and LDHA ...
Maoxiao Feng, Qinlian Jiao, Jiankang Zhu, Yidan Ren, Xiaoyu Teng, Xin Su, Zigan Li, Yuxuan Cai, Xiaoyan Liu, Yunshan Wang, Guangyong Zhang   +10 more
wiley   +1 more source

The atlas of brain glycosphingolipids revealed by selective enrichment and lipidomic profiling at multi-structural levels

, 2023
The atlas of brain glycosphingolipids revealed by selective enrichment and lipidomic profiling at multi-structural ...
Zidan Wang (17603220), Yu Xia (14495334)
core   +1 more source

Clinical symptom improvement and lipidomic signatures in overweight/obese PCOS treated by lifestyle and acupuncture intervention

Frontiers in Medicine
BackgroundPolycystic ovary syndrome (PCOS) is interrelated with obesity. Lifestyle intervention, mainly focusing on weight loss, has emerged as promising strategies to improve fertility outcomes in women with obesity.
Haolin Zhang, Haolin Zhang, Wenmin Tian, Dong Li, Dong Li, Yang Chen, Yang Ye, Yang Ye, Zejun Huo, Zejun Huo, Li Shi, Ii Fukuzawa, Ii Fukuzawa, Shuhan Yang, Shuhan Yang, Yang Yang, Yang Yang, Hua Zhang, Lin Zeng, Xiyan Xin, Xiyan Xin, Chunyong Wang, Wen Ma, Weiyu Qiu, Zhihui Qi, Heng Dai, Na Li, Haining Wang, Rong Li, Rong Li   +29 more
doaj   +1 more source