Results 181 to 190 of about 42,427 (286)

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Specific Lipidomic Shifts in Chronic Lymphocytic Leukemia at Diagnosis. [PDF]

Cancers (Basel)
Wojnicka J, Kiełbus M, Mertowska P, Mertowski S, Grywalska E, Sosnowski P, Wielgosz A, Kozub-Pędrak A, Sosnowska-Pasiarska B, Klatka M, Klatka J, Błażewicz A.   +11 more
europepmc   +1 more source

PPT1‐mediated plastidic phosphoenolpyruvate import enhances fatty acid biosynthesis in sugar‐rich tissues

New Phytologist, EarlyView.
Summary Metabolic engineering of vegetative tissues for lipid production holds transformative potential for sustainable biofuels, yet achieving sufficient yields remains challenging. Here, we present a strategy to enhance fatty acid synthesis by redirecting cytosolic phosphoenolpyruvate (PEP) into plastids through overexpression of the plastidial ...
Jiang Wang, Yi‐Hsuan Lin, Xueyi Xue, Gabriel Beuchat, Yaxin Li, Jiankun Li, Li‐Qing Chen   +6 more
wiley   +1 more source

Lipidomics and machine learning revealing dysregulation of specific triacylglycerol and phosphatidylglycerol as hub lipids associated with fetal growth in gestational diabetes mellitus. [PDF]

PeerJ
Lin Z, Li L, Fan Y, Chen H, Cai Y, Yang R, Chen M, Hong G.   +7 more
europepmc   +1 more source

Deciphering Cold Stress Resilience: Multiomics Insights in Contrasting Wheat Genotypes From the Western Himalayas

Plant Biotechnology Journal, EarlyView.
ABSTRACT Cold stress threatens wheat productivity, particularly in regions with extreme climatic conditions. To elucidate the molecular mechanisms underlying wheat's response to cold stress, we performed a multiomics analysis integrating lipidomics, transcriptomics, proteomics and metabolomics.
Sofora Jan, Farkhandah Jan, Mukesh Rathore, Yogita Singh, Prexha Kapoor, Palak Chaturvedi, Arindam Ghatak, Palakurthi Ramesh, Upendra Kumar, Manoj Prasad, Sundeep Kumar, Sachin Rustgi, Wolfram Weckwerth, Sanjay Kalia, Rajeev Kumar Varshney, Reyazul Rouf Mir   +15 more
wiley   +1 more source

Comment: in-depth cerebrovascular lipidomics profiling for discovering novel biomarkers and mechanisms in moyamoya and intracranial atherosclerotic disease. [PDF]

Int J Surg
Siyuan H, Yi J.
europepmc   +1 more source

Redundant Glycerol‐3‐Phosphate Acyltransferases Regulate Thermo‐Sensitive Genic Male Sterility in Rice

Plant Biotechnology Journal, EarlyView.
ABSTRACT Thermo‐sensitive genic male sterility (TGMS) lines play a pivotal role in two‐line hybrid rice breeding. However, the availability of elite TGMS germplasm remains limited, and the molecular mechanisms underlying fertility transition of TGMS lines are still poorly understood.
Siqi Cheng, Hai Zheng, Yunlu Tian, Chaolong Wang, Xiaowen Yu, Kun Dong, Jian Wang, Jiayu Lu, Keyi Chen, Xiaodong He, Kun Shao, Junwen Gao, Bowen Yao, Yang Hu, Zhenwei Xie, Ling He, Zhao Xie, Yuantao Zhu, Song Guo, Dekun Lei, Anqi Jian, Xufei Zhu, Hao Yu, Shihao Zhang, Minrui Chen, Yun Chen, Ling Jiang, Yulong Ren, Xiuping Guo, Shijia Liu, Xi Liu, Shanshan Zhu, Zhigang Zhao, Jianmin Wan   +33 more
wiley   +1 more source

Dapagliflozin induces renal lipidomic remodeling and systemic metabolic improvement. [PDF]

Biol Direct
Li A, Ye Y, Tang J, Hu J, Shi M, Wu Y, Ji C, Zhang H.   +7 more
europepmc   +1 more source

The phospholipase iPLA2γ is a major mediator releasing oxidized aliphatic chains from cardiolipin, integrating mitochondrial bioenergetics and signaling [PDF]

, 2017
Gross, Richard W, Guan, Shaoping, Jenkins, Christopher M, Li, Maoyin, Liu, Gao-Yuan, Moon, Sung Ho, Sims, Harold F   +6 more
core   +2 more sources

Angiotensin‐converting enzyme and exercise adaptations: Genetic variability, pharmacological modulation and future directions

The Journal of Physiology, EarlyView.
Abstract figure legend ACE I/D genotype, enzyme activity and integrated physiological adaptations. Upper panel: Conceptual framework linking the ACE I/D polymorphism (left) with circulating/tissue ACE activity (centre; violin plots based on hypothetical data for illustration) and strength/power versus endurance phenotypes (right).
Tórur Sjúrðarson, Nikolai B. Nordsborg   +1 more
wiley   +1 more source