Results 181 to 190 of about 23,923 (256)

Lipidomic analyses of large cohort studies define the role of lipid metabolism in bridging diet and cardio-metabolic health. [PDF]

Nat Commun
Beyene HB, Wang T, Cinel M, Mellett NA, Duong T, Buuren-Milne MV, Faulkner AN, Wu J, Olshansky G, Shaw JE, Magliano DJ, Southy MC, Milne RL, Hodge AM, Giles C, Huynh K, Meikle PJ.   +16 more
europepmc   +1 more source

Integrating Nuclear Magnetic Resonance into Bioprocess Control of Clinical‐Grade Extracellular Vesicle Manufacturing

Journal of Extracellular Vesicles, Volume 15, Issue 7, July 2026.
Nuclear magnetic resonance (NMR) in bioprocess design for the production of extracellular vesicles (EVs). NMR‐metabolomics enables real‐time bioprocess intelligence, bridging biological complexity with GMP rigor and accelerating the clinical translation of EV‐based therapies.
Santiago Roura, Núria Amigó, Joaquim Vives   +2 more
wiley   +1 more source

Fecal Proteomics Suggest Potential Biomarkers for Non‐Alcoholic Fatty Liver Disease and Steatohepatitis

PROTEOMICS – Clinical Applications, Volume 20, Issue 4, July 2026.
ABSTRACT Background and aims Non‐alcoholic Fatty Liver Disease (NAFLD) affects about a quarter of the world's population. Liver biopsy remains the gold standard for diagnosing the progressive form of NAFLD called Non‐alcoholic Steatohepatitis (NASH) but it is invasive, prone to sampling errors and observer variability, and impractical for widespread ...
Anna Negroni, Luisa Pieroni, Noemi Fiaschini, Francesca Palone, Mariateresa Mancuso, Roberta Vitali   +5 more
wiley   +1 more source

Plasma lipid trajectories improve prediction of future Alzheimer's disease. [PDF]

J Alzheimers Dis
Zou H, Wang T, Huynh K, Meikle PJ, Kaddurah-Daouk R, Luo S, Alzheimer's Disease Neuroimaging Initiative, Alzheimer's Disease Metabolomics Consortium.   +7 more
europepmc   +1 more source

Engineering Extracellular Vesicles for Anti‐Aging Therapy: Mechanisms, Applications, and Perspectives

Aging Cell, Volume 25, Issue 7, July 2026.
This review systematically elucidates the multifactorial anti‐aging mechanisms of extracellular vesicles (EVs). By bridging fundamental biology with advanced bioengineering, scalable manufacturing, and clinical translation, it establishes a comprehensive framework for developing next‐generation EVs‐based precision nanotherapeutics to combat systemic ...
Xian Huang, Qiujie Li, Guofang Tao, Xulin Gan, Jiangjie Lu, Sergei Krasny, Liyun Shi   +6 more
wiley   +1 more source

Lipidomic Signatures in Pediatric Metabolic Disorders. [PDF]

Metabolites
Narvaez-Rivas M, Setchell KDR.
europepmc   +1 more source

Bidirectional Relationship and Shared Mechanisms Between Sarcopenia and Osteoporosis: An Observational Study Integrating Genomic, Proteomic, and Metabolomic Data

Aging Cell, Volume 25, Issue 7, July 2026.
This study investigated the bidirectional relationship and shared mechanisms between sarcopenia and osteoporosis using data from the UK Biobank. Our findings indicated that the two conditions may act as reciprocal risk factors, with multiple potential biomarkers mediating the muscle‐bone relationship and suggested possible shared signals between the ...
Siqi Xu, Simin Wen, Xizeng Zong, Jianwei Zhu, Qiuling Du, Yu Li, Kunyan Wang, Peihua Cao, Changhai Ding, Yan Zhang, Guangfeng Ruan   +10 more
wiley   +1 more source

Therapeutic TG2 inhibition reverses systemic multiomic dysregulation in celiac disease. [PDF]

BMC Med
Dotsenko V, Le HH, Rajić S, Moulder R, Kettunen J, Hirvonen MK, Dickens AM, Hyötyläinen T, Tewes B, Zimmermann T, Mohrbacher R, Suomi T, Lehtimäki T, Lahesmaa R, Orešič M, Elo LL, Raitoharju E, Schuppan D, Mäki M, Viiri K, CEC-3 Investigators.   +20 more
europepmc   +1 more source

Advancing clinical precision medicine via peripheral blood immune single‐cell omics

Clinical and Translational Medicine, Volume 16, Issue 7, July 2026.
Liyang Li, Jialu Hu, Wanxin Duan, Yan‐Ming Xu, Jiaqiang Zhang, Xiangdong Wang   +5 more
wiley   +1 more source