Results 221 to 230 of about 23,923 (256)
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Profiling the Mammalian Lipidome by Quantitative Shotgun Lipidomics
2023The emerging field of lipidomics presents the systems biology approach to identify and quantify the full lipid repertoire of cells, tissues, and organisms. The importance of the lipidome is demonstrated by a number of biological studies on dysregulation of lipid metabolism in human diseases such as cancer, diabetes, and neurodegenerative diseases ...
Mads Møller, Foged +2 more
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Current Opinion in Clinical Nutrition and Metabolic Care, 2012
Lipidomics characterizes the composition of intact lipid molecular species in biological systems and the field has been driven by some spectacular advances in mass spectrometry instrumentation and applications. This review will highlight these advances and outline their recent application to address clinical issues.This review first identifies recent ...
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Lipidomics characterizes the composition of intact lipid molecular species in biological systems and the field has been driven by some spectacular advances in mass spectrometry instrumentation and applications. This review will highlight these advances and outline their recent application to address clinical issues.This review first identifies recent ...
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Metabolomics, Lipidomics, and Immunometabolism
2021Metabolomics, lipidomics, and the study of cellular metabolism are gaining increasing interest particularly in the field of immunology, since the activation and effector functions of immune cells are profoundly controlled by changes in cellular metabolic asset.
Carbone F. +8 more
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Prostaglandins & Other Lipid Mediators, 2005
Lipidomics the systematic decoding of lipid-based information in biosystems is comprised of identification and profiling of lipids and lipid-derived mediators. As practiced today, lipidomics can be subdivided into architecture/membrane-lipidomics and mediator-lipidomics. The mapping of structural components and their relation to cell activation as well
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Lipidomics the systematic decoding of lipid-based information in biosystems is comprised of identification and profiling of lipids and lipid-derived mediators. As practiced today, lipidomics can be subdivided into architecture/membrane-lipidomics and mediator-lipidomics. The mapping of structural components and their relation to cell activation as well
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2007
Lipids are recognized as key participants in the regulation and control of cellular function, having important roles in signal transduction processes. The diversity in lipid chemical structure presents a challenge for establishing practical methods to generate and manage high volumes of complex data that translate into a snapshot of cellular lipid ...
Eoin, Fahy +8 more
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Lipids are recognized as key participants in the regulation and control of cellular function, having important roles in signal transduction processes. The diversity in lipid chemical structure presents a challenge for establishing practical methods to generate and manage high volumes of complex data that translate into a snapshot of cellular lipid ...
Eoin, Fahy +8 more
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Quantitative Profiling of Lysosomal Lipidome by Shotgun Lipidomics
2017Recent studies have illuminated novel roles of lysosomes that go far beyond simple catabolism and function in the coordination of cellular metabolism and signaling. Promising therapeutic strategies emerge from knowledge in the molecular mechanisms and physiological roles of lipid metabolism in lysosomes.
Mesut Bilgin +3 more
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Lipidomics of Alzheimer’s Disease
Bioanalysis, 2014Alzheimer's disease (AD) is a progressive brain disease that leads to an irreversible loss of neurons and cognition. It is the most common cause of dementia and can be considered as a major public health problem. At the histological level, AD is characterized by senile plaques and neurofibrillary tangles.
Touboul, David, Gaudin, Mathieu
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2013
Lipids are a diverse group of compounds with multiple key biological functions. Lipidomics is a subdiscipline of metabolomics, with the focus on the global study of molecular lipids, including pathways and networks of cellular lipids in biological systems.
Pondia Pons Isabel, Hyötyläinen Tuulia
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Lipids are a diverse group of compounds with multiple key biological functions. Lipidomics is a subdiscipline of metabolomics, with the focus on the global study of molecular lipids, including pathways and networks of cellular lipids in biological systems.
Pondia Pons Isabel, Hyötyläinen Tuulia
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Analysis of the Mammalian Lipidome by DMS Shotgun Lipidomics
Shotgun Lipidomics is a robust methodology for the characterization of the lipidome of complex biological samples. This assay is among the most quantitative lipidomics methods and is capable of surveying a wide breadth of lipid subclasses, both neutral and polar.Baolong, Su, Kevin J, Williams
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Untargeted lipidomic approach in studying pinot noir wine lipids and predicting wine origin
Food Chemistry, 2021Elizabeth Tomasino
exaly