ABSTRACT Rationale The varied properties of metabolomics components dictate the tools used in mass spectrometry (MS) characterization including the selection of the ionization source. However, the ionization of select compounds limits characterization efficiency.
Madison Pursell +14 more
wiley +1 more source
Metabolic and lipidomic stability in EDTA plasma from hospitalized patients: impact of refrigerated storage time and additional freeze-thaw cycle. [PDF]
Guttorm SJT +8 more
europepmc +1 more source
Sphingosine‐1‐Phosphate Receptor 1 Promotes Ovarian Cancer Tumorsphere Proliferation and Metastasis
In high‐grade serous ovarian cancer, malignant ascites frequently arise as ovarian cancer cells shed from the primary tumor and aggregate into tumorspheres, severely limiting treatment success. To date, little is known about the mechanisms governing tumorsphere endurance and metastasis within the ascites once formed.
Núria Gendrau‐Sanclemente +12 more
wiley +1 more source
Outcomes and future activities of the 'Pan-European network in Lipidomics and EpiLipidomics - EpiLipidNET'. [PDF]
Kuligowski J +20 more
europepmc +1 more source
Abstract Tumor‐educated platelets (TEPs) are emerging as a compelling frontier in liquid biopsy, functioning as dynamic, systemic sensors that sequester and process tumor‐derived biomolecules. This interaction imprints an integrated molecular signature of malignancy—spanning the transcriptome, proteome, lipidome, and crucially, the captured genome ...
Whi‐An Kwon +5 more
wiley +1 more source
Plasma lipid trajectories improve prediction of future Alzheimer's disease. [PDF]
Zou H +7 more
europepmc +1 more source
Rapid Identification of Edible Insect Species in Food Using MALDI‐TOF Mass Spectrometry
ABSTRACT Rationale Edible insects are emerging as sustainable, nutritious ‘foods of the future’ and are gradually introduced to the European market as novel foods. Ensuring consumer safety and preventing fraud requires legal regulation, which in turn depends on reliable analytical methods.
David Straka +9 more
wiley +1 more source
Multi-omics integration reveals convergent extracellular matrix remodelling and lipid metabolic reprogramming as central axes of adipocyte differentiation from mouse embryonic stem cells. [PDF]
Al-Sayegh M +6 more
europepmc +1 more source
This study presents a multimatrix untargeted metabolomics analysis of fecal, plasma, and urine samples from individuals at high risk for pancreatic cancer development. Integrated multivariate and cofactor‐adjusted models were applied to characterize cross‐matrix metabolomic associations, incorporating pancreatic magnetic resonance imaging data, sex ...
Vladyslav Dovhalyuk +6 more
wiley +1 more source
Integrated Lipidomics and Flavoromics Analyses Reveal the Flavor Differences Between Breast and Leg Muscles of Xichuan Black-Boned Chicken. [PDF]
Zhou L +8 more
europepmc +1 more source

