Results 121 to 130 of about 42,745 (295)

Association of acylcarnitine species and diabetes incidence in a population-based apparently healthy cohort

Cardiovascular Diabetology. Endocrinology Reports
Background Current diabetes risk scores often fail to detect early metabolic changes. Acylcarnitines species (ACs), intermediates of mitochondrial fatty acid oxidation, may indicate early dysregulation in diabetes, but prospective evidence is limited. We
Ko Ko Maung, Rebecca Borreggine, Hector Gallart-Ayala, Julijana Ivanisevic, Pedro Marques-Vidal   +4 more
doaj   +1 more source

Application of lipidomics in the study of traditional Chinese medicine

Journal of Pharmaceutical Analysis
Lipidomics is an emerging discipline that systematically studies the various types, functions, and metabolic pathways of lipids within living organisms.
Yang Yang, Guangyi Yang, Wenpeng Zhang, Lingyi Xin, Jing Zhu, Hangtian Wang, Baodong Feng, Renyan Liu, Shuya Zhang, Yuanwu Cui, Qinhua Chen, Dean Guo   +11 more
doaj   +1 more source

Lipidomics informatics for life-science.

, 2017
Lipidomics encompasses analytical approaches that aim to identify and quantify the complete set of lipids, defined as lipidome in a given cell, tissue or organism as well as their interactions with other molecules. The majority of lipidomics workflows is
Ahrends, R., Schwudke, D., Hoffmann, N., R. Ahrends, A. Shevchenko, Hoffmann, Nils ; https://orcid.org/, Shevchenko, A., D. Schwudke, N. Hoffmann   +8 more
core   +1 more source

Membrane lipid metabolism as a regulatory frontier in neural crest biology: Roles for sphingolipids, cholesterol, and lipid rafts

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are multipotent, migratory stem‐like cells essential for vertebrate development that contribute broadly to many tissues including the craniofacial skeleton, peripheral nervous system, and pigment‐producing cells. Their development progresses through phases of induction, specification, delamination, migration, and ...
Allison E. Mancini, Mallorie P. Jenne, Michael L. Piacentino   +2 more
wiley   +1 more source

Untargeted plasma lipidomic profiling associated with pediatric metabolic dysfunction-associated steatohepatitis (MASH)

Lipids in Health and Disease
Background Altered lipid metabolism is central to the pathogenesis of MASH, yet lipidomic data in pediatric populations are limited. We conducted a cross-sectional analysis using high-resolution lipidomics to identify lipid alterations associated with ...
Gahyun Lim, Helaina E. Huneault, Chih-Yu Chen, Grey Won, Cristian Sanchez-Torres, Kristal Maner-Smith, Miriam B. Vos   +6 more
doaj   +1 more source

Implementation of Nano Flow Chromatography Coupled to Mass Spectrometry as a Reliable and Sensitive Discovery Lipidomics Platform. [PDF]

Rapid Commun Mass Spectrom
ABSTRACT Rationale Untargeted lipidomics is commonly performed at analytical flow rates, which consume more solvent and may require higher on‐column sample loads when sensitivity is limited by analyte abundance. Nano flow separations use lower flow rates and sample loads, reducing solvent consumption and facilitating improved electrospray ionization ...
Sallowicz CJ, Mattos T, Deshpande RR, Amer B, Bird SS.   +4 more
europepmc   +2 more sources

Lipidomics in nutrition and food research

, 2013
Lipids are a diverse class of metabolites that play several key roles in the maintenance of human health. Lipidomics, which focuses on the global study of molecular lipids in cells, tissues, and biofluids, has been advancing rapidly over the past decade.
Hyötyläinen, Tuulia,, Bondia-Pons, Isabel, Oresic, Matej,, Hyötyläinen, Tuulia, Orešič, Matej, Bondia-Pons, I.,   +5 more
core   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Postpartum lipid dysregulation in African American women who experienced cardiometabolic complications of pregnancy

iScience
Summary: African American women are disproportionately troubled with cardiometabolic complications of pregnancy (CMCPreg), including gestational diabetes, gestational hypertension, and preeclampsia.
Kristal Maner-Smith, Chih-Yu Chen, Zhenxin Hou, Xueyun Liu Gulbin, Jun Ahn, Eric A. Ortlund, Anne L. Dunlop, Erin Ferranti   +7 more
doaj   +1 more source

Untargeted lipidomics of CT26 cells

Untargeted lipidomics of 37°C-CT26 and 45°C-CT26 ...
Huang, Na
core   +1 more source