Exosomes containing HIV protein Nef reorganize lipid rafts potentiating inflammatory response in bystander cells. [PDF]
, 2019 HIV infection has a profound effect on "bystander" cells causing metabolic co-morbidities. This may be mediated by exosomes secreted by HIV-infected cells and containing viral factors.
Brichacek, Beda +15 more
core +3 more sources
Lipidomics in Health and Diseases - Beyond the Analysis of Lipids [PDF]
, 2014 published_or_final_versio
Fan, P, Li, M, Wang, Y
core +1 more source
Shotgun lipidomic analysis of chemically sulfated sterols compromises analytical sensitivity:Recommendation for large-scale global lipidome analysis [PDF]
, 2014 Shotgun lipidomics affords comprehensive and quantitative analysis of lipid species in cells and tissues at high-throughput [1 5]. The methodology is based on direct infusion of lipid extracts by electrospray ionization (ESI) combined with tandem mass ...
Casanovas, Albert +3 more
core +1 more source
Therapeutic efficacy of gut microbiota-derived polyphenol metabolite Urolithin A
Beni-Suef University Journal of Basic and Applied SciencesBackground Despite rising public awareness and improvements in diagnostic and treatment methods, there are adverse effects brought on by drug resistance, an increase in overall treatment costs, and unanticipated side effects from pharmaceuticals.
Shilpa S. Shetty +2 more
doaj +1 more source
Inborn Errors of Metabolism in the Era of Untargeted Metabolomics and Lipidomics. [PDF]
, 2019 Inborn errors of metabolism (IEMs) are a group of inherited diseases with variable incidences. IEMs are caused by disrupting enzyme activities in specific metabolic pathways by genetic mutations, either directly or indirectly by cofactor deficiencies ...
Fiehn, Oliver +2 more
core +2 more sources
Identification of a Widespread Palmitoylethanolamide Contamination in Standard Laboratory Glassware. [PDF]
, 2017 Introduction: Fatty acid ethanolamides (FAEs) are a family of lipid mediators that participate in a host of biological functions. Procedures for the quantitative analysis of FAEs include organic solvent extraction from biological matrices (e.g., blood ...
Angelini, Roberto +3 more
core
Lipidomics of Huntington’s Disease: A Comprehensive Review of Current Status and Future Directions
MetabolitesBackground: Huntington’s disease (HD) is a multifaceted neurological disorder characterized by the progressive deterioration of motor, cognitive, and psychiatric functions.
Ali Yilmaz +5 more
doaj +1 more source
Pregnancy lipidomic profiles and DNA methylation in newborns from the CHAMACOS cohort. [PDF]
, 2019 Lipids play a role in many biological functions and the newly emerging field of lipidomics aims to characterize the varying classes of lipid molecules present in biological specimens.
Bradman, Asa +5 more
core
Development of an R script for simple lipidomic and metabolomic data analysis [PDF]
, 2020 Background: Metabolomic and lipidomic studies generate vast quantities of data that are often analysed in a closed software environment with little to no access to the underlying algorithms.
Alshammari, Suad +4 more
core +1 more source
Nature CommunicationsRibosomes are regulated by evolutionarily conserved ubiquitination/deubiquitination events. We uncover the role of the deubiquitinase OTUD6 in regulating global protein translation through deubiquitination of the RPS7/eS7 subunit on the free 40 S ...
Sammy Villa +8 more
doaj +1 more source