Results 161 to 170 of about 32,392 (245)

Editorial: Lipid influence on lung immune-structural cell crosstalk: implications for respiratory health. [PDF]

Front Immunol
Allard B.
europepmc   +1 more source

Endogenous “Time Bomb” – Mislocalized Phospholipase A2 as a Critical Mediator of Ultra‐Rapid Mortality in Sepsis and Acute Lung Injury

Advanced Science, Volume 13, Issue 32, 9 June 2026.
Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang, Zhongxing Xu, Lin Wang, Xin Sui, Yuan Luo, Xiuli Zhao, Jun Yang, Yongan Wang   +7 more
wiley   +1 more source

Lipidomics-Based Investigation of the Effects of Ginsenoside FI on Free Fatty Acid-Induced Metabolism in HepG2 Cells. [PDF]

Pharmaceuticals (Basel)
Zhou J, Su DF, Chi YX, Chen QC, Huang YX, Chen SX, Liu S, Liu JH, Zhang WY.   +8 more
europepmc   +1 more source

Dry Deposition Strategies for MALDI–MS Imaging: Principles, Advances and Emerging Applications

Analytical Science Advances, Volume 7, Issue 1, June 2026.
ABSTRACT Matrix‐assisted laser desorption/ionisation mass spectrometry imaging (MALDI–MSI) has become a pivotal tool in biomedical research, enabling untargeted, spatially resolved analysis of molecular species in complex biological tissues. Among the critical steps in MALDI–MSI workflows, matrix deposition significantly influences sensitivity, spatial
Toufik Mahamdi, Oscar Yanes
wiley   +1 more source

Multiplexed LC-MS analysis reveals novel insights into grapevine defense mechanisms by expanding metabolome coverage. [PDF]

Metabolomics
Vásquez-Ocmín PG, Pérez A, Romeo-Oliván A, Puech-Pages V, Fournier S, Dumas B, Jacques A, Marti G.   +7 more
europepmc   +1 more source

Wooden‐Tip Electrospray Ionization Mass Spectrometry Combined With Machine Learning for Differentiating Thyroid Tumours

Analytical Science Advances, Volume 7, Issue 1, June 2026.
ABSTRACT Direct mass spectrometry (MS) analysis of human tissues at the molecular level has great potential for clinical diagnosis and biomarker discovery. However, conventional MS‐based analytical methods often require complicated and time‐consuming sample preparation, which limits their applicability in rapid clinical analysis.
Da‐Sheng Liu, Li Liu, Baixue Wang, Jianfeng Zhang, Hong‐Guo Lin, Xiang‐Xiong Huang, Kang‐Jian Deng, Yu‐Teng Zhou, Yunlong Pan, Bin Hu, Xue‐Yang Huang   +10 more
wiley   +1 more source

A Practical Roadmap for Clinical Translation of Metabolic Biomarkers: A Review. [PDF]

Int J Mol Sci
Kim KH, Yoo M, Choi MY, Yoo BC.
europepmc   +1 more source

Discrimination of Lipid Hydroperoxide Positional Isomers Using SFC– MS/MS With Sodium Ion: Its Application to Evaluating the Oxidation Mechanisms of Oxidized Oils

Journal of the American Oil Chemists' Society, Volume 103, Issue 6, Page 623-632, June 2026.
ABSTRACT Advanced lipid profiling relies on liquid chromatography–tandem mass spectrometry (LC–MS/MS), but long analysis times remain a challenge. Supercritical fluid chromatography (SFC)–MS/MS using supercritical carbon dioxide offers a faster and more environmentally friendly alternative.
Ryosuke Aoki, Masayoshi Sakaino, Junya Ito, Shunji Kato, Jun Imagi, Toshiro Sato, Kiyotaka Nakagawa   +6 more
wiley   +1 more source

Flaxseed feeding enriches plasmalogens and glycosphingolipids and alters the esterification site of PUFAs in egg yolk phospholipids based on lipidomics analysis. [PDF]

Food Chem X
Wang Y, Cheng L, Zhang M, Ma Y, Dong L, Li Y, Fang B.   +6 more
europepmc   +1 more source