ABSTRACT Soybean (Glycine max L.) is the world's most important oilseed crop, supplying 25% of world‘s edible oil and 66% of feed protein. This review address genomic innovations to overcome yield constraints and climate vulnerability (especially drought stress) in high‐oil soybean breeding.
Mujeeb Ur Rehman +7 more
wiley +1 more source
A Membrane-Centric Plasma Lipidomic Signature of Response to Long-Acting Naltrexone in Alcohol Use Disorder. [PDF]
Huang L +5 more
europepmc +1 more source
Oxysterols in Cancer: From Biosynthesis and Pathophysiology to Targeted Therapeutics
Mechanisms by which oxysterol targeting may enhance immunotherapy efficacy. This figure illustrates potential metabolic interventions that may improve antitumor immunity by modulating oxysterol related pathways. CH25H modulation may reduce 25‐HC accumulation, promote the conversion of cold tumors into hot tumors, and increase T cell infiltration and PD‐
Haili Shang, Yongsheng Li
wiley +1 more source
Oil as a Hindrance to Oat (<i>Avena sativa</i> L.) Nutrient Fractionation: Leveraging Mass Spectrometry-Based Omics to Unravel Lipid Regulation for Functional Crop Improvement. [PDF]
Lau D +3 more
europepmc +1 more source
ERβ activation restores glucose and lipid homeostasis by remodeling the hepatic lipidome. Mechanistically, it promotes complete fatty acid oxidation and decreases Acetyl‐CoA levels, leading to reduced ketogenesis and lipotoxicity, as demonstrated through in vivo and in vitro approaches.
Debora Santos Rocha +9 more
wiley +1 more source
Placental insufficiency is a thromboinflammatory disorder driven by angiogenic imbalance, complement activation, endothelial dysfunction and coagulation dysregulation, leading to microvascular thrombosis, impaired uteroplacental perfusion and adverse maternal and fetal outcomes, including pre‐eclampsia, fetal growth restriction and stillbirth. Abstract
Emmanuel Ifeanyi Obeagu
wiley +1 more source
Development of plant‐derived biomimetic nanoparticles as a novel targeted drug delivery platform
Plant‐derived biomimetic nanoparticles (PD‐BNPs) represent a sustainable and biocompatible nanoplatform for targeted drug delivery. This review highlights their therapeutic potential, engineering strategies, and translational challenges toward precision nanomedicine applications. Abstract Plant‐derived biomimetic nanoparticles (PD‐BNPs) have emerged as
Jihad Hasan +3 more
wiley +1 more source
Mesenchymal stem cell‐derived exosomes (MSC‐sEVs) show preclinical promise for cardiac repair via anti‐inflammatory, anti‐apoptotic, pro‐angiogenic and anti‐fibrotic effects. However, translational hurdles remain, including non‐standardized isolation, unvalidated potency assays, incomplete GMP manufacturing, and lack of completed Phase II/III trials ...
Sakhavat Abolhasani +2 more
wiley +1 more source
Bovine Milk Polar Lipids: Lipidomics Advances and Functional Perspectives. [PDF]
Fappani G +3 more
europepmc +1 more source
SMASH Imaging: A Serial Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Strategy for High-Resolution Imaging Facilitates Dual-Polarity and MS2 Spatial Lipidomics on a Single Tissue Section. [PDF]
Uchino H, Tsugawa H, Arita M.
europepmc +1 more source

