Results 11 to 20 of about 3,736 (191)
Insect Molecular Biology, Volume 32, Issue 6, Page 658-675, December 2023., 2023 Nutritional starvation of honey bee colonies has long‐term negative consequences on honey production, even after the colonies were left to recover on good floral resources. Nutritional stress in honey bees leads to increased unsaturations of stored lipids.
Clara E. Castaños +6 more
wiley +1 more source
Advances in therapies for neurological lysosomal storage disorders
Journal of Inherited Metabolic Disease, Volume 46, Issue 5, Page 874-905, September 2023., 2023 Abstract Lysosomal Storage Disorders (LSDs) are a diverse group of inherited, monogenic diseases caused by functional defects in specific lysosomal proteins. The lysosome is a cellular organelle that plays a critical role in catabolism of waste products and recycling of macromolecules in the body.
S. Ellison, H. Parker, B. Bigger
wiley +1 more source
Equine Veterinary Education, Volume 35, Issue 6, Page 311-320, June 2023., 2023 Summary Background Hyperinsulinaemia‐associated laminitis (HAL) is encountered commonly in equine practice. There are currently no registered medications which specifically target hyperinsulinaemia in horses and ponies. Sodium–glucose cotransporter 2 inhibitors (SGLT2i) have been demonstrated to limit post‐prandial insulin responses and prevent the ...
Tania Sundra, Erin Kelty, David Rendle
wiley +1 more source
Veterinary Dermatology, Volume 33, Issue 5, Page 402-406, October 2022., 2022 Abstract Background In humans, the acidic pH of the ear canal plays a protective role against infection and a change towards alkalinity of the external auditory canal (EAC) is a local factor in the progression of acute to chronic otitis externa (OE).
Pauline Panzuti +5 more
wiley +1 more source
Food Science &Nutrition, Volume 10, Issue 1, Page 115-121, January 2022., 2022 In infancy, the diet requires both, an especially high nutritional quality and toxicological safety. In view of the recent TDI for erucic acid issued by EFSA, our scenarios show that the nutritionally safe food‐based dietary guidelines for infancy in Germany may no longer be safe with regard to potential exposure to erucic acid that originates mainly ...
Mathilde Kersting +4 more
wiley +1 more source
Clinical and genetic analysis of lipoprotein glomerulopathy patients caused by APOE mutations
Molecular Genetics &Genomic Medicine, Volume 8, Issue 8, August 2020., 2020 For the first time APOE‐Osaka/Kurashiki and APOE‐Chicago mutations reported in Chinese; Lipoprotein glomerulopathy (LPG) patients with urine protein remission had slower renal function decrease; LPG was associated with higher blood pressure; Serum apoE levels were higher in patients with low‐density lipoprotein receptor binding region mutations of APOE
Mingxin Yang +13 more
wiley +1 more source
Traffic, Volume 21, Issue 1, Page 60-75, January 2020., 2020 Over the last decade, we witnessed an unprecedented interest in lysosomes, most prominently as catabolic centers and as intracellular signaling platforms. Interestingly, lysosomal activity is strongly dependent on organelle numbers, size and position. The dynamic nature of lysosomes has been extensively documented but the importance of lysosomal size ...
Mariana E. G. de Araujo +3 more
wiley +1 more source
Clinical Cardiology, 2018 We read with great interest the recently published article by Di et al. about the impact of bradyarrhythmias on the left atrial dysfunction in Fabry's disease1 .
R. Desai, H. K. Fong, H. Goyal
semanticscholar +1 more source
Metabolomic studies of lipid storage disorders, with special reference to Niemann-Pick type C disease: a critical review with future perspectives [PDF]
, 2020 Lysosomal storage disorders (LSDs) are predominantly very rare recessive autosomal neurodegenerative diseases.Sphingolipidoses, a sub-group of LSDs, result from defects in lysosomal enzymes involved in sphingolipid catabolism, and feature disrupted ...
Gibson, M +4 more
core +2 more sources
Better a Broader Diagnosis Than a Misdiagnosis: The Study of a Neoplastic Condition in a Male Individual who Died in Early 20th Century (Coimbra, Portugal) [PDF]
, 2013 The paleopathological record of neoplastic conditions in the past is considered scarce. The detection of tumours in ancient populations is hindered by the quality and quantity of signs visible on the skeleton, the methodological approach, the ...
Cunha, Eugénia +2 more
core +2 more sources