Results 31 to 40 of about 2,988 (157)
Estudos sobre o xanthoma: biochimica e pathogenia Studies in xanthoma: biochemistry and pathogenesis
Memorias do Instituto Oswaldo Cruz, 1935 1. No presente trabalho são descriptos dois casos de xanthelasmatose (xanthoma) com perturbações accentuadas do metabolismo dos lipides e esteroes. 2. Um dos casos apresentou notavel cholesteroluria não mostrando o doente lesões renaes, ao passo que o ...
Gilberto G. Villela, Rabello Junior
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Cherry Anthocyanins Regulate NAFLD by Promoting Autophagy Pathway
Oxidative Medicine and Cellular Longevity, Volume 2019, Issue 1, 2019., 2019 Nonalcoholic fatty liver disease (NAFLD) is a common chronic disease that threatens human health, and present therapies remain limited due to the lack of effective drugs. Lipid metabolic disturbance and oxidative stress have strong links to the development of NAFLD, while autophagy was generally accepted as a key regulatory mechanism on these steps ...
Qiang Chu +7 more
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Lipid Storage Myopathy in Behçet′s Disease: A Rare Cause of Elevated Serum Creatine Kinases Levels
Case Reports in Rheumatology, Volume 2012, Issue 1, 2012., 2012 Muscular involvement in Behçet’s disease is rare and there are only a few case reports in the literature. The causes of elevated muscle enzymes in a patient with Behcet’s disease are many, including myositis, drug‐induced myopathy, metabolic myopathy, and the disease itself.
Sedat Yilmaz +9 more
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Journal of Toxicology, Volume 2012, Issue 1, 2012., 2012 While phospholipidosis is thought to be an adaptive response to chemical challenge, many phospholipogenic compounds are known to display adverse effects in preclinical species and humans. To investigate the link between phospholipogenic administration and incidence of preclinical histological signals, an internal AstraZeneca in vivo toxicology report ...
Linda R. Barone +5 more
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Gaucher Disease and the Synucleinopathies
BioMed Research International, Volume 2006, Issue 1, 2006., 2006 Several recent observations suggest a connection between Gaucher disease, the inherited deficiency of glucocerebrosidase, and the synucleinopathies. Rare patients have been observed who develop both Gaucher disease and parkinsonism. Autopsy studies on these subjects reveal synuclein‐positive Lewy bodies and inclusions.
Kathleen S. Hruska +2 more
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Functional Ecology, Volume 40, Issue 6, Page 1906-1920, June 2026.Read the free Plain Language Summary for this article on the Journal blog. Abstract Human‐driven landscape change, particularly urbanization, is reshaping pollinator communities, yet the functional traits that mediate species persistence remain poorly understood. Dietary specialization is commonly used to predict species vulnerability.
Yan Yang +5 more
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Muscle &Nerve, Volume 71, Issue 2, Page 229-236, February 2025.ABSTRACT Introduction/Aim Patients with myotonic dystrophy type1 (DM1) have reduced lifespan. This study aimed to quantify mortality risks, and evaluate causes and time trends in DM1. Methods We identified 1021 DM1 patients and 15,104 matched DM1‐free controls from the United Kingdom (UK) Clinical Practice Research Datalink.
Rotana Alsaggaf +5 more
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Old disease—New reflections: Gaucher, immunity, and inflammation
Journal of Cellular and Molecular Medicine, Volume 28, Issue 20, October 2024.Abstract Gaucher disease (GD) is the most common lysosomal storage disease. It is a multisystemic metabolic disease caused by GBA pathogenic mutations. Although the general symptoms have been known for a long time, new treatment possibilities, the detection of different biomarkers, and innovations in diagnosis and follow‐up have paved the way for ...
Can Veysel Şoroğlu, Ezgi Gizem Berkay
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History of study on metabolic myopathy
Chinese Journal of Contemporary Neurology and Neurosurgery, 2014 The developmental history of metabolic myopathy is reviewed both chronologically and from different classifications. Searching the specific biomarkers of different metabolic myopathies, and specific diagnostic and therapeutic measures targeting these ...
Jian YIN +4 more
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