Results 11 to 20 of about 3,245 (185)

Morphological Characteristics of Peripheral Blood Cells in Patients with Neutral Lipid Storage Disease with Myopathy and Literature Review [PDF]

Zhongguo quanke yixue, 2022
Background Neutral lipid storage disease with myopathy (NLSDM) has obscure onset and nonspecific clinical symptoms. Due to different clinical manifestations, the patients with NLSDM may be seen in neurology, cardiovascular disease and other departments ...
Ying XING, Chengwei PU, Ke SHANG, Chenxue QU
doaj   +1 more source

Direct activation of the fibroblast growth factor-21 pathway in overweight and obese cats

Frontiers in Veterinary Science, 2023
IntroductionFeline obesity is common, afflicting ~25–40% of domestic cats. Obese cats are predisposed to many metabolic dyscrasias, such as insulin resistance, altered blood lipids, and feline hepatic lipidosis.
Emily J. Brinker, Emily J. Brinker, T. Jordan Towns, T. Jordan Towns, Rie Watanabe, Xiaolei Ma, Xiaolei Ma, Adil Bashir, Robert C. Cole, Xu Wang, Xu Wang, Xu Wang, Xu Wang, Emily C. Graff, Emily C. Graff   +14 more
doaj   +1 more source

Lipidomic features of honey bee and colony health during limited supplementary feeding Características lipidómicas de la abeja melífera y salud de la colonia durante dietas suplementarias restringidas

Insect Molecular Biology, Volume 32, Issue 6, Page 658-675, December 2023., 2023
Nutritional starvation of honey bee colonies has long‐term negative consequences on honey production, even after the colonies were left to recover on good floral resources. Nutritional stress in honey bees leads to increased unsaturations of stored lipids.
Clara E. Castaños, Mary C. Boyce, Tiffane Bates, A. Harvey Millar, Gavin Flematti, Nathan G. Lawler, Julia Grassl   +6 more
wiley   +1 more source

Iron Overload Protects from Obesity by Ferroptosis

Foods, 2021
Dysregulation in iron metabolism is associated with obesity, type 2 diabetes, and other metabolic diseases, whereas the underlying mechanisms of imbalanced glycolipid metabolism are still obscure.
Wan Ma, Li Jia, Qingqing Xiong, Huahua Du   +3 more
doaj   +1 more source

Advances in therapies for neurological lysosomal storage disorders

Journal of Inherited Metabolic Disease, Volume 46, Issue 5, Page 874-905, September 2023., 2023
Abstract Lysosomal Storage Disorders (LSDs) are a diverse group of inherited, monogenic diseases caused by functional defects in specific lysosomal proteins. The lysosome is a cellular organelle that plays a critical role in catabolism of waste products and recycling of macromolecules in the body.
S. Ellison, H. Parker, B. Bigger
wiley   +1 more source

Preliminary observations on the use of ertugliflozin in the management of hyperinsulinaemia and laminitis in 51 horses: A case series

Equine Veterinary Education, Volume 35, Issue 6, Page 311-320, June 2023., 2023
Summary Background Hyperinsulinaemia‐associated laminitis (HAL) is encountered commonly in equine practice. There are currently no registered medications which specifically target hyperinsulinaemia in horses and ponies. Sodium–glucose cotransporter 2 inhibitors (SGLT2i) have been demonstrated to limit post‐prandial insulin responses and prevent the ...
Tania Sundra, Erin Kelty, David Rendle
wiley   +1 more source

Effect of an ear cleaner instillation containing lipacids in a model of re‐acidification of the external auditory canal in dogs

Veterinary Dermatology, Volume 33, Issue 5, Page 402-406, October 2022., 2022
Abstract Background In humans, the acidic pH of the ear canal plays a protective role against infection and a change towards alkalinity of the external auditory canal (EAC) is a local factor in the progression of acute to chronic otitis externa (OE).
Pauline Panzuti, Marion Mosca, Oscar Fantini, Guillaume Noel, Julien Cappelle, Didier Pin   +5 more
wiley   +1 more source

Erucic acid exposure during the first year of life—Scenarios with precise food‐based dietary guidelines

Food Science &Nutrition, Volume 10, Issue 1, Page 115-121, January 2022., 2022
In infancy, the diet requires both, an especially high nutritional quality and toxicological safety. In view of the recent TDI for erucic acid issued by EFSA, our scenarios show that the nutritionally safe food‐based dietary guidelines for infancy in Germany may no longer be safe with regard to potential exposure to erucic acid that originates mainly ...
Mathilde Kersting, Hermann Kalhoff, Bernd Honermeier, Kathrin Sinningen, Thomas Lücke   +4 more
wiley   +1 more source

The Pathogenic Sphingolipid Psychosine is Secreted in Extracellular Vesicles in the Brain of a Mouse Model of Krabbe Disease

ASN Neuro, 2022
Psychosine exerts most of its toxic effects by altering membrane dynamics with increased shedding of extracellular vesicles (EVs). In this study, we discovered that a fraction of psychosine produced in the brain of the Twitcher mouse, a model for Krabbe ...
Cory R. Reiter, Rima Rebiai, Angelika Kwak, Jeff Marshall, Dylan Wozniak, Giusepe Scesa, Duc Nguyen, Emily Rue, Koralege C. Pathmasiri, Robert Pijewski, Richard van Breemen, Stephanie Cologna, Stephen J. Crocker, M Irene Givogri, Ernesto R Bongarzone   +14 more
doaj   +1 more source

Lipidomic analysis identifies age-disease-related changes and potential new biomarkers in brain-derived extracellular vesicles from metachromatic leukodystrophy mice

Lipids in Health and Disease, 2022
Background Recent findings show that extracellular vesicle constituents can exert short- and long-range biological effects on neighboring cells in the brain, opening an exciting avenue for investigation in the field of neurodegenerative diseases ...
Melissa R. Pergande, Christina Kang, Diann George, Pearl A. Sutter, Stephen J. Crocker, Stephanie M. Cologna, Maria I. Givogri   +6 more
doaj   +1 more source