Results 91 to 100 of about 1,507,099 (358)
Theory of tunable pH sensitive vesicles of anionic and cationic lipids or anionic and neutral lipids [PDF]
, 2001 The design of vesicles which become unstable at an easily tuned value of pH is of great interest for targeted drug delivery. We present a microscopic theory for two forms of such vesicles.
Bell +34 more
core +3 more sources
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
FEBS Letters, EarlyView.Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
AntioxidantsIn order to evaluate whether telomere maintenance is associated with type 2 diabetes remission, newly diagnosed type 2 diabetes patients without glucose-lowering treatment (183 out of 1002) from the CORDIOPREV study (NCT00924937) were randomized to ...
Ana Ojeda-Rodriguez +13 more
doaj +1 more source
Revista de la Facultad de Medicina, 2016 Introduction: Nutritional vulnerability is more evident during childhood, since malnutrition has an impact on academic performance and is linked to different diseases during this period. Likewise, an increase in the incidence and prevalence of obesity in
Jenifer Tatiana Figueroa +3 more
doaj +1 more source
The Physics of Stratum Corneum Lipid Membranes [PDF]
, 2015 The Stratum Corneum (SC), the outermost layer of skin, comprises rigid corneocytes (keratin filled dead cells) in a specialized lipid matrix. The continuous lipid matrix provides the main barrier against uncontrolled water loss and invasion of external pathogens.
arxiv +1 more source
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Enhanced lipid extraction from unbroken microalgal cells using enzymes [PDF]
, 2015 The marine microalga Nannochloropsis sp. was chosen as a model organism to investigate the feasibility of using cell wall-degrading enzymes to enhance the recovery of intracellular lipids.
Familiari, Giuseppe +7 more
core +1 more source
FEBS Letters, EarlyView.The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang +2 more
wiley +1 more source
Microscopic Description of Thermodynamics of Lipid Membrane at Liquid-Gel Phase Transition [PDF]
, 2018 A microscopic model of the lipid membrane is constructed that provides analytically tractable description of the physical mechanism of the first order liquid-gel phase transition. We demonstrate that liquid-gel phase transition is cooperative effect of the three major interactions: inter-lipid van der Waals attraction, steric repulsion and hydrophobic ...
arxiv +1 more source
Generation and quality control of lipidomics data for the alzheimers disease neuroimaging initiative cohort. [PDF]
, 2018 Alzheimers disease (AD) is a major public health priority with a large socioeconomic burden and complex etiology. The Alzheimer Disease Metabolomics Consortium (ADMC) and the Alzheimer Disease Neuroimaging Initiative (ADNI) aim to gain new biological ...
AA Willette +42 more
core +2 more sources