Results 181 to 190 of about 661,416 (267)

Fatty acid esters of hydroxy fatty acids and alkyl-diacylglycerols: minor but bioactive components in human milk. [PDF]

Biochem Soc Trans
Lee MLX, Elejalde U, Cazenave-Gassiot A.
europepmc   +1 more source

Gardiquimod Nanoemulsion Targets Cutaneous Leishmaniasis Lesions Reducing Systemic Toxicity and Parasite Burden

Advanced Healthcare Materials, EarlyView.
Nanoemulsion delivery of a TLR7 agonist enhances safety and promotes colocalization with Leishmania‐infected macrophages in skin lesions, enabling a ∼2‐log reduction in parasite burden. However, tissue‐level constraints and TLR‐driven regulatory feedback generate a mixed immune response that limits complete parasite clearance.
Carmen Palomino‐Cano, M. Carmen Mera‐Delgado, Esther Moreno, Esther Larrea, Lecnia Aguirre, Jonathan Miguel Zanatta, Sónia Barros‐Carvalho, Iola F. Duarte, Ricardo Silvestre, Juan M. Irache, Javier Carrión, Socorro Espuelas   +11 more
wiley   +1 more source

Immune cell-mediated effects of plasma lipids on heart failure: A two-step, two-sample Mendelian randomization study. [PDF]

Medicine (Baltimore)
Liu Z, Kwaku E, Cui Y, Xiong L, Li S, Zeng L, Du L, Wang K, Zheng J, Luo D, Zeng G, Yue R.   +11 more
europepmc   +1 more source

Nanoplatforms for Sentinel and Tumor‐Draining Lymph Node Mapping: From Visualization to Pathway‐Informed Staging

Advanced Healthcare Materials, EarlyView.
Lymphotropic nanoplatforms integrate multimodal imaging with therapeutic guidance to map sentinel and tumor‐draining lymph nodes, revealing functional drainage, metastatic involvement, and nodal accessibility, while providing mechanistic insight to support precision surgical and therapeutic interventions.
Xu Chen, Nina Li, Meiyan Zou, Zihao Zhou, Rongwei Xu, Weiyao Feng, Xinyuan Zhao, Li Cui   +7 more
wiley   +1 more source

From the unknown to spotlight: newly identified hormone adjusts hepatic cholesterol synthesis to dietary uptake

Signal Transduction and Targeted Therapy
Yakum Bertrand Nkeh, Resul Gökberk Elgin, Gesine Saher   +2 more
doaj   +1 more source

Lipidomic signatures of CNS ischemic injury and their modulation by immunomodulatory hydrogels.

Analyst
Wang MF, Ouyang Y, Segura T, Muddiman DC.   +3 more
europepmc   +1 more source

Identification of <i>iso</i>-diabolic acid-based tetraester and mixed ether/ester membrane-spanning lipids in members of the Bacillota provides insight into the biosynthesis of bacterial branched glycerol dialkyl glycerol tetraethers. [PDF]

Appl Environ Microbiol
Sahonero-Canavesi DX, Bale NJ, Antony Venancius M, Koenen M, Hopmans EC, Sinninghe Damsté JS, Villanueva L.   +6 more
europepmc   +1 more source

Temporal Immune and Metabolic Shifts Drive the Anti‐Tumor Efficacy of Resiquimod‐Loaded Nanoparticles in Peritoneal Carcinomatosis

Advanced Healthcare Materials, EarlyView.
Peritoneal carcinomatosis is a hard‐to‐treat spread of abdominal cancers that often returns after therapy. Nanoparticles were developed to retain an immune‐boosting drug in the abdomen. When combined with chemotherapy in mice, this approach eliminated tumors in many cases and prevented recurrence, helping the immune system mount a stronger, longer ...
Vanessa Chan, Po‐Han Chao, XuXin Sun, Jun Han, Sarah MacPherson, Lucas J. Andrew, Noah Y. Brittain, Tien Do, Marcel B. Bally, Julian J. Lum, Shyh‐Dar Li   +10 more
wiley   +1 more source

Lipidome Analysis of Cancer Cells and Their Extracellular Vesicles Reveals Cancer-Type-Specific Lipid Signatures and Enables the Design of EV-Mimetic Liposomes. [PDF]

J Extracell Vesicles
Douanne N, Benslimane Y, López RR, Bustamante P, Tsering T, Chen Y, Kienzle L, Ghasemi M, Taylor L, Chen Y, Boutin AT, Juncker D, Mounier C, Nerguizian V, Burnier JV.   +14 more
europepmc   +1 more source