Results 211 to 220 of about 274,692 (266)
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Annual Review of Physiology, 1977
Since this is the first review on lipids to appear in the Annual Review of Physiology, it should cover the spectrum of the functional roles of lipids: (a) as fuel; (b) as membrane components; (c) in blood coagulation; (d) as components of immune systems; (e) as vitamins and hormones; and (j) in interfacial phenomena (e.g.
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Since this is the first review on lipids to appear in the Annual Review of Physiology, it should cover the spectrum of the functional roles of lipids: (a) as fuel; (b) as membrane components; (c) in blood coagulation; (d) as components of immune systems; (e) as vitamins and hormones; and (j) in interfacial phenomena (e.g.
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Lipids and Lipid Derivatives for RNA Delivery
Chemical Reviews, 2021RNA-based therapeutics have shown great promise in treating a broad spectrum of diseases through various mechanisms including knockdown of pathological genes, expression of therapeutic proteins, and programmed gene editing. Due to the inherent instability and negative-charges of RNA molecules, RNA-based therapeutics can make the most use of delivery ...
Yuebao Zhang +4 more
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Lipid and Non-lipid Effects of Statins
2005Long- and short-term trials with the 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) have demonstrated significant reductions in cardiovascular events in patients with and without history of coronary heart disease. Statins are well-established low-density lipoprotein (LDL)-lowering agents, but their clinical benefit is believed to ...
PAOLETTI R +2 more
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Current Drug Metabolism, 2012
Lysosomes are cytoplasmic organelles delimited by a single membrane and filled with a variety of hydrolytic enzymes active at acidic pH and collectively capable to degrade the vast majority of macromolecules entering lysosomes via endocytosis, phagocytosis or autophagy.
Hamer, Isabelle +3 more
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Lysosomes are cytoplasmic organelles delimited by a single membrane and filled with a variety of hydrolytic enzymes active at acidic pH and collectively capable to degrade the vast majority of macromolecules entering lysosomes via endocytosis, phagocytosis or autophagy.
Hamer, Isabelle +3 more
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Physical studies of lipid‐lipid and lipid‐protein interactions
Lipids, 1969AbstractThis is a review of studies of lipid‐lipid and lipid‐protein interactions conducted in the author's laboratory. Studies of the thermotropic mesomorphism of phospholipids and effects due to the presence of water are described. The relevance of these thermal transitions to monolayer, bilayer and membrane systems is discussed.
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The Interfacial Tension of the Lipid Membrane Formed From Lipid–Cholesterol and Lipid–Lipid Systems
Cell Biochemistry and Biophysics, 2006Interfacial tension has been determined for phosphatidylcholine-cholesterol, phosphatidylcholine-phosphatidylethanolamine, and phosphatidylethanolamine-cholesterol membranes. Phosphatidylcholine (PC), phosphatidylethanolamine (PE), and cholesterol (Ch) were to be investigated, because of their presence in biological membranes.
Aneta D, Petelska +2 more
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Lipid Packing in Lipid-Wrapped Nanoparticles
The Journal of Physical Chemistry B, 2018Equilibrium simulations of lipid-wrapped nanoparticles (LNP) were performed using a hybrid molecular dynamics/Monte Carlo (MD/MC) approach. The radius, R, of a spherical nanoparticle (NP) core was adjusted with MC moves while a surrounding lipid bilayer was treated with MD.
David Stelter, Tom Keyes
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Lipids: Alkenones, Polar Lipids, and Ether Lipids
2011This chapter focuses on several classes of polar lipids, including alkenones, which are di-, tri-, and tetra-unsaturated long-chain ketones. These compounds are produced by a restricted number of species of prymnesiophyte algae (coccolithophorid alga Emiliania huxleyi), living over a wide temperature range.
Thomas S. Bianchi, Elizabeth A. Canuel
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Lipidized dermatofibromas and their relationship to serum lipids
Journal of the American Academy of Dermatology, 2006Lipidized dermatofibromas represent a rare variant of dermatofibroma that has been regarded as an incidental finding with no particular clinical significance.The goal of this study was to investigate the relationship between lipidized dermatofibromas and patient age, anatomic location, and serum total cholesterol.A retrospective case control format was
Kyle, Wagamon +6 more
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Analysis of Lipids and Lipid Rafts in Borrelia
2017Lipid rafts are membrane microdomains that are involved in cellular processes such as protein trafficking and signaling processes, and which play a fundamental role in membrane fluidity and budding. The lipid composition of the membrane and the biochemical characteristics of the lipids found within rafts define the ability of cells to form microdomains
Alvaro, Toledo +3 more
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