Results 281 to 290 of about 2,513,452 (406)

Predictive Lung- and Spleen-Targeted mRNA Delivery with Biodegradable Ionizable Lipids in Four-Component LNPs. [PDF]

Pharmaceutics
Heredero J, Peña Á, Broset E, Blandín B, de Miguel D, Alejo T, Toro A, Mata E, López-Gavín A, Gallego-Lleyda A, Casabona D, Lampaya V, Larraga A, Pérez-Herrán E, Luna D, Orera I, Romanos E, García A, Martínez-Oliván J, Giménez-Warren J.   +19 more
europepmc   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

Advanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan, Simona Summonte, Fabrizio Ricci, Matthias Sandmeier, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

Sexual dimorphism in the association of umbilical cord blood lipidome with abdominal fat in early childhood. [PDF]

BMC Med
Narasimhan K, Tint MT, Chen L, Mir SA, Sadananthan SA, Michael N, Ramasamy A, Tan KM, Mishra P, Bendt AK, Tan KH, Cameron-Smith D, Chong YS, Gluckman PD, Meikle PJ, Leow MKS, Yap F, Lee YS, Yng CS, Eriksson JG, Velan SS, Karnani N, Wenk MR.   +22 more
europepmc   +1 more source

THE INFLUENCE OF AGE AND DIET ON THE LIPID COMPOSITION OF THE RAT

, 1945
Harold H. Williams, Harry Galbraith, Mildred Kaucher, Icie G. Macy   +3 more
openalex   +1 more source

Double Cross‐Linked Hydrogel for Intra‐articular Injection as Modality for Macrophages Metabolic Reprogramming and Therapy of Rheumatoid Arthritis

Advanced Functional Materials, EarlyView.
A hydrogel for intra‐articular injection for the treatment of rheumatoid arthritis (RA) is formulated and comprehensively studied. After administration, the hydrogel induces a metabolic reprogramming of immunometabolism of macrophages to trigger fatty acid oxidation subsequently inducing polarization of anti‐inflammatory M2 macrophages. This results in
Yutong Song, Valentin A. Milichko, Ziqiao Ding, Wen Li, Bei Kang, Yunsheng Dou, Sona Krizkova, Zbynek Heger, Nan Li   +8 more
wiley   +1 more source

Bilayer-Forming Lipids Enhance Archaeal Monolayer Membrane Stability. [PDF]

Int J Mol Sci
Saracco M, Schaeffer P, Tourte M, Albers SV, Louis Y, Peters J, Demé B, Fontanay S, Oger PM.   +8 more
europepmc   +1 more source

LIPIDS OF THE FASTING MOUSE

, 1942
P.L. MacLachlan, Harold C. Hodge, W.R. Bloor, Eileen A. Welch, Frederick L. Truax, J.D. Taylor   +5 more
openalex   +1 more source

Transmembrane Activation of Catalysis and Protein Refolding in Synthetic Cells by Enzymes and Nanozymes

Advanced Functional Materials, EarlyView.
Synthetic cells are engineered herein to respond to an external chemical messenger by the activation of intracellular catalysis. The chemical messenger molecules are catalytically generated by an extracellular enzyme or a mineral surface, whereas the intracellular catalysis emerges via direct enzyme activation or via protein refolding.
Dante G. Andersen, Andreas B. Pedersen, Mireia Casanovas Montasell, Søren Moesgaard, Anja Bille Bohn, Alexander N. Zelikin   +5 more
wiley   +1 more source

Single-lipid tracking reveals heterogeneities in the nanoscale dynamics of colloid-supported lipid bilayers.

Soft Matter
Gascoigne L, Tas RP, Moerman PG, Voets IK.   +3 more
europepmc   +1 more source

Taxon-specific redox conditions control fossilisation pathways. [PDF]

Nat Commun
Corthésy N, Antcliffe JB, Saleh F.
europepmc   +1 more source