Results 51 to 60 of about 1,286,040 (309)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Nutrition & DiabetesBackground Type 2 diabetes mellitus (T2DM) is currently a major global public health problem. Although disease remission is possible, few biomarkers have been identified which can help us select the diet that best promotes remission. Our aim was to study
Juan Francisco Alcala-Diaz +13 more
doaj +1 more source
Scientific Reports, 2021 In patients with coronary artery disease (CAD), further increasing the level of high-density lipoprotein (HDL) cholesterol (HDL-C) as an add-on to statins cannot reduce cardiovascular risk.
Xiaoyu Tang +8 more
doaj +1 more source
Dual Role of Vitamin C-Encapsulated Liposomal Berberine in Effective Colon Anticancer Immunotherapy
Pharmaceuticals, 2023 The aim of the study was to achieve effective colon anticancer immunotherapy using the alkaloid berberine. In the presented paper we attempt to develop a formulation of berberine loaded into liposomal carriers using the vitamin C gradient method ...
Martyna Mianowska +5 more
doaj +1 more source
Flexible Lipid Bilayers in Implicit Solvent
, 2005 A minimalist simulation model for lipid bilayers is presented. Each lipid is represented by a flexible chain of beads in implicit solvent. The hydrophobic effect is mimicked through an intermolecular pair potential localized at the ``water''/hydrocarbon ...
A. Ben-Shaul +14 more
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Cardiovascular DiabetologyBackground Type 2 diabetes mellitus (T2DM) is a growing global health challenge. Conventional diagnostic tools have limited sensitivity and specificity for early-stage disease.
Hatim Boughanem +13 more
doaj +1 more source
Biomedicines, 2021 Excess inflammation and canonical BMP receptor (BMPR) signaling are coinciding hallmarks of the early stages of injury-induced endochondral heterotopic ossification (EHO), especially in the rare genetic disease fibrodysplasia ossificans progressiva (FOP).
Huili Lyu +4 more
doaj +1 more source
Synthesis and Characterization of Lipid Coated Nanoparticles as Drug Delivery Vehicles [PDF]
, 2017 Spherical monodisperse nanoparticles composed of gold or silver cores were modified with lipids as part of an ongoing project to utilize functionalized nanoparticles as drug delivery vehicles.
Gilbert, Brian D. +1 more
core +1 more source
Microalgae cultivation for lipids and carbohydrates production [PDF]
, 2017 Microalgae are photoautotrophic microorganisms that can produce energy both by using sunlight, water and CO2 (phototrophic metabolism) and by using organic sources such as glucose (heterotrophic metabolism).
Altimari, Pietro +7 more
core +1 more source