Results 151 to 160 of about 949 (209)
This randomized, placebo‐controlled trial compared the effects of low‐ and moderate‐dose alcohol on biomarkers related to chronic disease in light and heavy drinkers. We identified novel acute alcohol effects as well as between‐group differences suggestive of pathophysiological processes by which alcohol use may promote chronic disease.
Mollie A. Monnig +2 more
wiley +1 more source
Adipokine secretion from adipose tissue may be involved in obesity‐related asthma, but it is unknown how adipokine levels relate to asthma characteristics. Plasma adipokines were measured in well‐characterized lean, overweight or obese patients with mild‐to‐moderate or severe asthma.
Lars I. Andersson +20 more
wiley +1 more source
Most reactions are toxic–irritant, driven by epithelial injury and neuro‐inflammatory activation. IgE‐mediated allergy is less common but may cause immediate systemic reactions. Endotype differentiation guides diagnosis, risk stratification and management.
Prasad Dasari +9 more
wiley +1 more source
Targeting m6A Modifications Regulating Ferroptosis Offers Novel Therapy in Diseases
m6A RNA modification regulates ferroptosis by balancing iron metabolism, lipid peroxidation, and antioxidant defenses. Dysregulated m6A signaling disrupts pro‐ and anti‐ferroptotic factors, leading to excess ROS, Fe3+ accumulation, and lipid peroxidation–driven cell death. Targeting m6A‐mediated ferroptotic regulation represents a promising therapeutic
Lida Du +7 more
wiley +1 more source
ABSTRACT Vitamin A (retinol and retinyl esters) is present in substantial amounts in the urine of healthy adult dogs, but the mechanisms affecting its excretion are poorly understood. To assess whether the onset of urinary vitamin A excretion is dependent on dietary vitamin A intake, breed, and/or parameters of kidney function, 48 puppies from two ...
Jens Raila +2 more
wiley +1 more source
As lipocalinas constituem uma família de pequenas proteínas extracelulares com cerca de 200 resíduos de aminoácidos e massa molecular de 20 Kda possuem forte divergência em suas sequências de aminoácidos mas mantêm a sua estrutura tridimensional ...
Soares, Adriano Carlos
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