Results 61 to 70 of about 16,730 (235)

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

open access: yesBMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang   +6 more
wiley   +1 more source

LipocalinPred: a SVM-based method for prediction of lipocalins

open access: yesBMC Bioinformatics, 2009
Background Functional annotation of rapidly amassing nucleotide and protein sequences presents a challenging task for modern bioinformatics. This is particularly true for protein families sharing extremely low sequence identity, as for lipocalins, a ...
Gupta Dinesh, Ramana Jayashree
doaj   +1 more source

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

open access: yesBMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng   +4 more
wiley   +1 more source

Control of metabolic homeostasis by stress signaling is mediated by the lipocalin NLaz. [PDF]

open access: yesPLoS Genetics, 2009
Metabolic homeostasis in metazoans is regulated by endocrine control of insulin/IGF signaling (IIS) activity. Stress and inflammatory signaling pathways--such as Jun-N-terminal Kinase (JNK) signaling--repress IIS, curtailing anabolic processes to promote
Julie Hull-Thompson   +6 more
doaj   +1 more source

Interaction of ceramides and tear lipocalin [PDF]

open access: yesBiochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2018
The distribution of lipids in tears is critical to their function. Lipids in human tears may retard evaporation by forming a surface barrier at the air interface. Lipids complexed with the major lipid binding protein in tears, tear lipocalin, reside in the bulk (aqueous) and may have functions unrelated to the surface. Many new lipids species have been
Glasgow, Ben J, Abduragimov, Adil R
openaire   +4 more sources

Exercise‐specific plasma proteomic signatures in racehorses: Candidates for training adaptation and peak load monitoring

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Racehorses undergo profound physiological changes with training and competition, but current biomarkers inadequately capture the complex molecular dynamics of exercise. This study aimed to identify novel plasma biomarkers of training adaptation and peak load using high‐throughput proteomics.
Jowita Grzędzicka   +4 more
wiley   +1 more source

Functional and genomic characterization of LCN2-deficient PC-3 cells reveals insights into prostate cancer progression

open access: yesFrontiers in Molecular Biosciences
IntroductionProstate Cancer-3 (PC-3) cells, commonly used as a model for aggressive, androgen-independent prostate cancer, display numerous genetic alterations that contribute to advanced disease, including the loss of tumor suppressors and dysregulated ...
Kiara Gäberlein   +8 more
doaj   +1 more source

Structure and stability of recombinant bovine odorant-binding protein: I. Design and analysis of monomeric mutants [PDF]

open access: yesPeerJ, 2016
Bovine odorant-binding protein (bOBP) differs from other lipocalins by lacking the conserved disulfide bond and for being able to form the domain-swapped dimers.
Olga V. Stepanenko   +5 more
doaj   +2 more sources

Mammalian Siderophores, Siderophore-binding Lipocalins, and the Labile Iron Pool*

open access: yesJournal of Biological Chemistry, 2012
Bacteria use tight-binding, ferric-specific chelators called siderophores to acquire iron from the environment and from the host during infection; animals use proteins such as transferrin and ferritin to transport and store iron.
C. Correnti, R. Strong
semanticscholar   +1 more source

The plant Apolipoprotein D ortholog protects Arabidopsis against oxidative stress

open access: yesBMC Plant Biology, 2008
Background Lipocalins are a large and diverse family of small, mostly extracellular proteins implicated in many important functions. This family has been studied in bacteria, invertebrate and vertebrate animals but little is known about these proteins in
Houde Mario   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy