Results 41 to 50 of about 16,730 (235)
Structural and ligand binding analysis of the pet allergens Can f 1 and Fel d 7
Frontiers in Allergy, 2023 IntroductionPet lipocalins are respiratory allergens with a central hydrophobic ligand-binding cavity called a calyx. Molecules carried in the calyx by allergens are suggested to influence allergenicity, but little is known about the native ligands ...
Jungki Min +7 more
doaj +1 more source
N-Glycosylation of Lipocalin 2 Is Not Required for Secretion or Exosome Targeting
Frontiers in Pharmacology, 2018 Lipocalin 2 (LCN2) is a highly conserved secreted adipokine acting as a serum transport protein for small hydrophobic molecules such as fatty acids and steroids.
Erawan Borkham-Kamphorst +4 more
doaj +1 more source
Mouse Lipocalins (MUP, OBP, LCN) Are Co-expressed in Tissues Involved in Chemical Communication
Frontiers in Ecology and Evolution, 2016 Chemical communication is mediated by signal production and signal perception and in house mice (Mus musculus), both processes involve lipocalin proteins (OBP, MUP, LCN) that transport volatiles and protect them in tissues where they are produced ...
R. Stopková +8 more
semanticscholar +1 more source
Scientific Reports, 2016 Evolution has provided ticks with an arsenal of bioactive saliva molecules that counteract host defense mechanisms. This salivary pharmacopoeia enables blood-feeding while enabling pathogen transmission. High-throughput sequencing of tick salivary glands
J. Valdés +5 more
semanticscholar +1 more source
Neurobiology of Disease, 2023 Stroke is the second leading cause of death worldwide; however, the treatment choices available to neurologists are limited in clinical practice. Lipocalin 2 (LCN2) is a secreted protein, belonging to the lipocalin superfamily, with multiple biological functions in mediating innate immune response, inflammatory response, iron-homeostasis, cell ...
Ruo-Yu Zhao +8 more
openaire +3 more sources
Ligand binding complexes in lipocalins: Underestimation of the stoichiometry parameter (n)
Biochimica et Biophysica Acta - Proteins and Proteomics, 2018 The stoichiometry of a ligand binding reaction to a protein is given by a parameter (n). The value of this parameter may indicate the presence of protein monomer or dimers in the binding complex. Members of the lipocalin superfamily show variation in the
B. Glasgow, A. Abduragimov
semanticscholar +1 more source
Clinical and Molecular Allergy, 2017 BackgroundMultiple sensitizations in early age have been reported to be a risk for development of asthma. This study evaluates the emergence and evolution of IgE to aeroallergens among a cohort of children with physician-diagnosed atopic dermatitis and ...
M. Nagao +8 more
semanticscholar +1 more source
Neuro - Open Journal, 2015 Stroke is a leading cause of adult disability in the United States. However, limited number of molecularly targeted therapy exists for stroke. Recent studies have shown that Li-pocalin-2 (LCN2) is an acute phase protein mediating neuroinflammation after ischemic and hemorrhagic strokes.
Chou, Wen-Hai +3 more
openaire +2 more sources
On the tear proteome of the house mouse (Mus musculus musculus) in relation to chemical signalling [PDF]
PeerJ, 2017 Mammalian tears are produced by lacrimal glands to protect eyes and may function in chemical communication and immunity. Recent studies on the house mouse chemical signalling revealed that major urinary proteins (MUPs) are not individually unique in Mus ...
Romana Stopkova +3 more
doaj +2 more sources
Allergy. European Journal of Allergy and Clinical Immunology, 2015 Owners and their domestic animals via skin shedding and secretions, mutually exchange microbiomes, potential pathogens and innate immune molecules. Among the latter especially lipocalins are multifaceted: they may have an immunomodulatory function and ...
Erika Jensen-Jarolim +4 more
semanticscholar +1 more source