Results 51 to 60 of about 949 (209)
Lazarillo-related Lipocalins confer long-term protection against type I Spinocerebellar Ataxia degeneration contributing to optimize selective autophagy [PDF]
, 2015 A diverse set of neurodegenerative disorders are caused by abnormal extensions of polyglutamine (poly-Q) stretches in various, functionally unrelated proteins. A common feature of these diseases is altered proteostasis. Autophagy induction is part of the
Ganfornina, María D. +7 more
core +2 more sources
PLoS ONE, 2019 The Lipocalin family is a group of homologous proteins characterized by its big array of functional capabilities. As extracellular proteins, they can bind small hydrophobic ligands through a well-conserved β-barrel folding.
Andres Mejias +4 more
doaj +1 more source
Revista Alergia México, 2016 Background: Lipocalins seem to explain the cross-reactivity between some pets like cat and dog. However, little has been studied its role in other animals and its possible clinical impact in allergy diseases.
Andrés Sánchez +2 more
doaj +1 more source
European Journal of Cell Biology, 2023 The acrosome located within the mammalian sperm head is essential for successful fertilization, as it enables the sperm to penetrate the extracellular layers of the oocyte and fuse with oolemma.
Tereza Otčenášková +6 more
doaj +1 more source
Interaction of ceramides and tear lipocalin [PDF]
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2018 The distribution of lipids in tears is critical to their function. Lipids in human tears may retard evaporation by forming a surface barrier at the air interface. Lipids complexed with the major lipid binding protein in tears, tear lipocalin, reside in the bulk (aqueous) and may have functions unrelated to the surface. Many new lipids species have been
Glasgow, Ben J, Abduragimov, Adil R
openaire +4 more sources
Advanced Science, EarlyView.Glucocorticoids transcriptionally activate LCN2 expression via GR nuclear translocation. Secreted LCN2 binds MMP9 to degrade skeletal muscle ECM collagen, blocks integrin‐mediated mechanotransduction, bidirectionally disrupts muscle protein homeostasis, and reveals a novel target for steroid‐induced muscle atrophy.
Hongwei Shi +11 more
wiley +1 more source
Comparison of the cavity capping residues of lipocalins.
, 2019 In Can f 6, at the entrance of the calyx cavity His87 in L5 stabilizes L1 over the ligand binding mouth. Arg41 and Asp91 stabilizes His87 and the L1 loop and are highly conserved indicating a common capping mechanism between lipocalins.
John W. Kappler (7387661) +4 more
core +1 more source
Comparison of thermal stability of different lipocalins with change in pH.
, 2023 Sandercyanin Fluorescent Protein (SFP) and cellular retinoic acid binding protein 1(CRABP1) are lipocalins that are structurally like Lili-Mip-2. Yet they do not show a significant change in thermal stability as compared to Lili-Mip-2.
Ramaswamy Subramanian (616227) +6 more
core +1 more source
CellsOlfactory perception depends on soluble proteins in the perireceptor environment that support odorant transport, mucosal protection, and tissue homeostasis.
Juchan Ha +3 more
doaj +1 more source
Lipocalin-2 and Cerebral Stroke
Frontiers in Molecular Neuroscience, 2022 Stroke is a common and devastating disease with an escalating prevalence worldwide. The known secondary injuries after stroke include cell death, neuroinflammation, blood-brain barrier disruption, oxidative stress, iron dysregulation, and neurovascular unit dysfunction.
Chao Luo +7 more
openaire +3 more sources