Results 31 to 40 of about 949 (209)
Structure, Functions, and Physiological Roles of the Lipocalin α1-Microglobulin (A1M)
α1-microglobulin (A1M) is found in all vertebrates including humans. A1M was, together with retinol-binding protein and β-lactoglobulin, one of the three original lipocalins when the family first was proposed in 1985.
Jesper Bergwik +5 more
doaj +1 more source
N-Glycosylation of Lipocalin 2 Is Not Required for Secretion or Exosome Targeting
Lipocalin 2 (LCN2) is a highly conserved secreted adipokine acting as a serum transport protein for small hydrophobic molecules such as fatty acids and steroids.
Erawan Borkham-Kamphorst +4 more
doaj +1 more source
Structural and ligand binding analysis of the pet allergens Can f 1 and Fel d 7
IntroductionPet lipocalins are respiratory allergens with a central hydrophobic ligand-binding cavity called a calyx. Molecules carried in the calyx by allergens are suggested to influence allergenicity, but little is known about the native ligands ...
Jungki Min +7 more
doaj +1 more source
Substrate prediction of Ixodes ricinus salivary lipocalins differentially expressed during Borrelia afzelii infection. [PDF]
Evolution has provided ticks with an arsenal of bioactive saliva molecules that counteract host defense mechanisms. This salivary pharmacopoeia enables blood-feeding while enabling pathogen transmission. High-throughput sequencing of tick salivary glands
Růžek, D +12 more
core +1 more source
Expression level differences of Lipocalins.
(A) Abundance levels of human and murine Lipocalins, expressed in normalized parts per million (ppm) and retrieved from PaxDb 4.1 (https://pax-db.org/), were ranked and normalized to the whole-integrated proteome.
Sergio Diez-Hermano (3738445) +4 more
core +1 more source
The role of the host—Neutrophil biology
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Tick saliva helps blood feeding by its antihemostatic and immunomodulatory activities. Tick salivary gland transcriptomes (sialotranscriptomes) revealed thousands of transcripts coding for putative secreted polypeptides.
Melina Garcia Guizzo +3 more
doaj +1 more source
Stroke is a leading cause of adult disability in the United States. However, limited number of molecularly targeted therapy exists for stroke. Recent studies have shown that Li-pocalin-2 (LCN2) is an acute phase protein mediating neuroinflammation after ischemic and hemorrhagic strokes.
Chou, Wen-Hai +3 more
openaire +2 more sources
Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird +9 more
wiley +1 more source
Characterization of two novel lipocalins expressed in the Drosophila embryonic nervous system [PDF]
We have found two novel lipocalins in the fruit fly Drosophila melanogaster that are homologous to the grasshopper Lazarillo, a singular lipocalin within this protein family which functions in axon guidance during nervous system development.
Bastiani, Michael J. +4 more
core +1 more source

