Results 11 to 20 of about 949 (209)
Antibiotic Capture by Bacterial Lipocalins Uncovers an Extracellular Mechanism of Intrinsic Antibiotic Resistance [PDF]
mBio, 2017 The potential for microbes to overcome antibiotics of different classes before they reach bacterial cells is largely unexplored. Here we show that a soluble bacterial lipocalin produced by Burkholderia cenocepacia upon exposure to sublethal antibiotic ...
Omar M. El-Halfawy +6 more
doaj +6 more sources
Journal of Structural Biology: X, 2022 Anticalins are generated via combinatorial protein design on the basis of the lipocalin protein scaffold and constitute a novel class of small and robust engineered binding proteins that offer prospects for applications in medical therapy as well as in ...
S. Achatz, A. Jarasch, A. Skerra
doaj +2 more sources
LipocalinPred: a SVM-based method for prediction of lipocalins [PDF]
BMC Bioinformatics, 2009 Background Functional annotation of rapidly amassing nucleotide and protein sequences presents a challenging task for modern bioinformatics. This is particularly true for protein families sharing extremely low sequence identity, as for lipocalins, a ...
Gupta Dinesh, Ramana Jayashree
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, 2006 Less than a decade has elapsed since the publication in 2000 of the first anthology devoted to lipocalins (Biochim Biophys Acta 1482, 2000), and only a few years since the first Lipocalin International Symposium in Copenhagen in 2003 (Benzon Symposium no.
Salier, Jean-Philippe +3 more
openaire +2 more sources
The Three Lipocalins of Egg-White: Only Ex-FABP Inhibits Siderophore-Dependent Iron Sequestration by Salmonella Enteritidis [PDF]
Frontiers in Microbiology, 2020 Salmonella Enteritidis is the most prevalent food-borne pathogen associated with egg-related outbreaks in the European Union. During egg colonization, S.
Louis Alex Julien +11 more
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Ixodes ricinus tick lipocalins: identification, cloning, phylogenetic analysis and biochemical characterization. [PDF]
PLoS ONE, 2008 BACKGROUND: During their blood meal, ticks secrete a wide variety of proteins that interfere with their host's defense mechanisms. Among these proteins, lipocalins play a major role in the modulation of the inflammatory response.
Jérôme Beaufays +9 more
doaj +3 more sources
Human lipocalins bind and export fatty acids through the secretory pathway of yeast cells [PDF]
Frontiers in MicrobiologyThe activation of fatty acids to their acyl-CoA derivatives is a crucial step for their integration into more complex lipids or their degradation via beta-oxidation.
Aslihan Ekim Kocabey, Roger Schneiter
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Tear Lipocalin and Lipocalin-Interacting Membrane Receptor [PDF]
Frontiers in Physiology, 2021 Tear lipocalin is a primate protein that was recognized as a lipocalin from the homology of the primary sequence. The protein is most concentrated in tears and produced by lacrimal glands. Tear lipocalin is also produced in the tongue, pituitary, prostate, and the tracheobronchial tree. Tear lipocalin has been assigned a multitude of functions.
openaire +3 more sources
Hepatology, EarlyView., 2022 Graphical summary of obesity‐induced NASH progression by LCN2 targeted to HSC activation. Abstract Background and Aims In obesity and type 2 diabetes mellitus, leptin promotes insulin resistance and contributes to the progression of NASH via activation of hepatic stellate cells (HSCs).
Kyung Eun Kim +12 more
wiley +1 more source
Hepatology, EarlyView., 2022 Diagnostic and prognostic ability of urinary NGAL in patients with cirrhosis and AKI. Abstract Background and Aims Acute kidney injury (AKI) commonly occurs in patients with decompensated cirrhosis. Urinary neutrophil gelatinase–associated lipocalin (uNGAL) could help discriminate between different etiologies of AKI.
Carmine Gambino +14 more
wiley +1 more source