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Dimerization of lipocalin allergens [PDF]
AbstractLipocalins are one of the most important groups of inhalant animal allergens. The analysis of structural features of these proteins is important to get insights into their allergenicity. We have determined two different dimeric crystal structures for bovine dander lipocalin Bos d 2, which was earlier described as a monomeric allergen.
Miettinen Ilja +5 more
openaire +3 more sources
Structural similarities of human and mammalian lipocalins, and their function in innate immunity and allergy [PDF]
Owners and their domestic animals via skin shedding and secretions, mutually exchange microbiomes, potential pathogens and innate immune molecules. Among the latter especially lipocalins are multifaceted: they may have an immunomodulatory function and ...
Jensen Jarolim, Erika +4 more
core +2 more sources
Endonuclease activity in lipocalins [PDF]
Several lipocalins contain conserved amino acid sequences similar to the phosphodiester bond cleavage domain of sugar non-specific magnesium-dependent nucleases of the Serratia marcescens type. His-89 and Glu-127 of the S. marcescens endonuclease are believed to have a role in the active catalytic site by the attack of a water molecule at the ...
T N, Yusifov +3 more
openaire +2 more sources
The diversity of lipocalin receptors
Lipocalins are important carriers of preferentially hydrophobic molecules, but they can also bind other ligands, like highly polar siderophores or intact proteins. Consequently, they are involved in a variety of physiological processes in many species.
Bernhard Redl, Matthias Habeler
openaire +2 more sources
Lipocalins represent the most important protein family of the mammalian respiratory allergens. Four of the seven named dog allergens are lipocalins: Can f 1, Can f 2, Can f 4, and Can f 6.
Gina M Clayton +4 more
doaj +1 more source
NMR structure of lipoprotein YxeF from Bacillus subtilis reveals a calycin fold and distant homology with the lipocalin Blc from Escherichia coli. [PDF]
The soluble monomeric domain of lipoprotein YxeF from the Gram positive bacterium B. subtilis was selected by the Northeast Structural Genomics Consortium (NESG) as a target of a biomedical theme project focusing on the structure determination of the ...
Yibing Wu +10 more
doaj +1 more source
Background/Aims: A diagnosis of hepatorenal syndrome (HRS) is based on a differential evaluation of acute kidney injury (AKI), which may aggravate the clinical course.
Jong Ho Lee +7 more
doaj +1 more source
Transcriptome data on salivary lipocalin family of the Asiatic Triatoma rubrofasciata
The dataset in this report is related to the research article entitled: “Salivary gland transcriptome of the Asiatic Triatoma rubrofasciata” [1]. Lipocalin family proteins were identified as the dominant component in T.
Daiki Mizushima +4 more
doaj +1 more source
Comparative diagnostic value of NGAL and multibiomarker models in pediatric sepsis-associated acute kidney injury in Indonesia: a preliminary study [PDF]
Purpose Sepsis is a leading cause of pediatric critical illness and a major contributor to acute kidney injury (AKI). Sepsis-associated AKI (SA-AKI) worsens outcomes, yet current diagnostic criteria based on serum creatinine and urine output lack ...
Fina Meilyana Andriyani +4 more
doaj +1 more source
Neutrophil gelatinase-associated lipocalin as a predictor of treatment outcomes in primary glomerulonephritis [PDF]
Background/Aim. Biomarkers for predicting disease course could facilitate treatment selection in primary glomerulonephritis (PGN). Data on the role of neutrophil gelatinase-associated lipocalin (NGAL) in PGN are limited.
Stražmešter-Majstorović Gordana +5 more
doaj +1 more source

