Results 31 to 40 of about 836 (156)

High-risk whole lung lavage for an unprecedented oil drowning situation: Management issues from a respiratory therapist's perspective

Indian Journal of Respiratory Care, 2021
Bilateral whole lung lavage (WLL), a complex procedure involving large volume saline washes of both lungs is a standard treatment for pulmonary alveolar proteinosis.
Anmol Hanamant Thorbole, Hari Prasad, Sameer Bansal, Ravindra Mehta   +3 more
doaj   +1 more source

Tissue‐Resident Macrophage in Inflammation and Cancer

MedComm, Volume 7, Issue 9, September 2026.
Opposing macrophage functions in inflammation and cancer converge on shared mechanistic nodes, informing cross‐disease therapeutic strategies. ABSTRACT Tissue‐resident macrophages (TRMs) are long‐lived immune cells strategically distributed across organs, where their functional plasticity enables both homeostatic maintenance and pathological ...
Siyuan Huang, Jiangbo Fan, Wenyi Liu, Di Liu, Rui Wang, Yuanyang Wang, Jianhui Sun, Huacai Zhang, Qingli Cai, Zhe Xu, Fang Xu, Jianxin Jiang, Zhen Wang, Ling Zeng   +13 more
wiley   +1 more source

The 2025 ATS/ERS update of the international multidisciplinary classification of the interstitial pneumonias: implications for the pathologist

Histopathology, Volume 89, Issue 3, Page 403-425, September 2026.
This review highlights changes relevant to pathologists in the updated multidisciplinary classification of interstitial pneumonias. Changes include expansion beyond idiopathic disease, subclassification as interstitial (fibrotic vs non‐fibrotic) and alveolar filling disorders, expansion to include additional patterns (e.g.
Andrew G Nicholson, Wendy A. Cooper, Aurelie Fabre, William Travis, Lida P. Hariri, Ayodeji Adegunsoye, Sara Piciucchi, Christopher J Ryerson   +7 more
wiley   +1 more source

Age‐Dependent Differences in Canakinumab Safety: A Comprehensive Pharmacovigilance Analysis Using the FAERS Database

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT While the efficacy of canakinumab, an anti‐interleukin‐1β monoclonal antibody, is well‐established, its safety profile, particularly across different age groups, remains inadequately explored. Using the FDA Adverse Event Reporting System (FAERS) database, this study evaluated postmarketing safety by analyzing adverse event (AE) reports from ...
Youyang Wang, Ngasin Lam, Xiaoming Huang, Yang Jiao   +3 more
wiley   +1 more source

Molecular analysis of lipoid proteinosis: identification of a novel nonsense mutation in the ECM1 gene in a Pakistani family

Diagnostic Pathology, 2011
Lipoid proteinosis is a rare autosomal recessive disease characterized by cutaneous and mucosal lesions and hoarseness appearing in early childhood that is caused by homozygous or compound heterozygous mutations in the ECM1 gene located on chromosome ...
Naeem Muhammad, Qamar Reem, Ajmal Muhammad, Latif Amir, Nasir Muhammad, Hameed Abdul   +5 more
doaj   +1 more source

Secondary Pulmonary Alveolar Proteinosis Associated With Ruxolitinib After Bone‐Marrow Transplantation: A Case With Transient Improvement Following Drug Discontinuation

Respirology Case Reports, Volume 14, Issue 6, June 2026.
Secondary pulmonary alveolar proteinosis (PAP) may occur in patients receiving ruxolitinib for steroid‐refractory GVHD after bone marrow transplantation. In this case, a 47‐year‐old woman developed respiratory failure 8 months after commencing ruxolitinib therapy, and initial radiological and clinical improvements occurred after drug withdrawal, prior ...
Taiki Yanagi, Maki Asami‐Noyama, Kaoru Yamamoto, Yoshinobu Hoshii, Yasushi Ichiyama, Masatoshi Okimura, Tetsuya Fujii, Junki Suizu, Misa Harada, Keita Murakawa, Kazuki Hamada, Toshiaki Utsunomiya, Yoriyuki Murata, Keiji Oishi, Nobutaka Edakuni, Tomoyuki Kakugawa, Tsunahiko Hirano, Kazuto Matsunaga   +17 more
wiley   +1 more source

Characterization of Pulmonary Dysfunction in Systemic Juvenile Idiopathic Arthritis Using Xenon and Proton MRI

Pediatric Pulmonology, Volume 61, Issue 4, April 2026.
ABSTRACT Introduction Systemic juvenile idiopathic arthritis‐associated lung disease (SJIA‐LD) is increasingly recognized and associated with potentially life‐threatening complications. Diagnosis is challenging as SJIA‐LD is complex and frequently presents with subtle or no respiratory symptoms, necessitating CT imaging or other tests to detect budding
William J. Garrison, Matthew M. Willmering, Bilal I. Masokano, Shipra Rai, Antoinette Wannes Daou, David J. Roach, Esi M. Morgan, Jason C. Woods, Zackary I. Cleveland, Emrah Gecili, R. Paul Guillerman, Andrew H. Schapiro, Grant S. Schulert, Alexei A. Grom, Christopher T. Towe, Laura L. Walkup   +15 more
wiley   +1 more source

Significant but Temporary Efficacy of Statin for a Patient With Severe Autoimmune Pulmonary Alveolar Proteinosis: A Case Report

Respirology Case Reports, Volume 14, Issue 2, February 2026.
Evidence of the efficacy of statins in pulmonary alveolar proteinosis is limited and remains controversial. We report a case of severe autoimmune pulmonary alveolar proteinosis in a patient who underwent whole‐lung lavage therapy twice and achieved excellent response and remarkable clinical resolution of respiratory failure after the initiation of oral
Fumihiko Makino, Kohei Shibayama, Yuki Muto, Rie Hayakawa, Kenta Izumi, Yohei Suzuki, Osamu Nagashima, Shinichi Sasaki, Kazuhisa Takahashi   +8 more
wiley   +1 more source

Doença de Urbach-Wiethe/proteinose lipoidica.

Acta Médica Portuguesa, 1998
The authors present a case of Urbach-Wiethe's disease (lipoid proteinosis), a rare autosomal recessive disorder, in a 49-year-old female patient with pathognomonic cranial radiological findings demonstrated by radiology and computed tomography.
R Maia, L Teixeira, J Drago
doaj   +1 more source

Imaging Findings of Pediatric Rheumatic Disorders: JIA in the PRINTO Era and Autoimmune Interferonopathies

Pediatrics International, Volume 68, Issue 1, January/December 2026.
ABSTRACT Treatment strategies for pediatric rheumatic diseases have changed substantially over the past two decades, driven by the development of biologics and cytokine‐targeted molecular therapy. Therapeutic approaches that modulate both innate and adaptive immune responses have improved prognosis in these immune‐mediated disorders, and early ...
Yuko Tsujioka, Yoshitake Yamada, Gen Nishimura, Tatsuo Kono, Masahiro Jinzaki   +4 more
wiley   +1 more source