Results 51 to 60 of about 787 (149)

Skin‐Colored Papules on the Face and Chest of a Female Patient

Clinical Case Reports, Volume 13, Issue 9, September 2025.
ABSTRACT Scleromyxedema is an unpredictable but progressive disease and can be lethal due to systemic involvement if not diagnosed timely. Hence, we require a keen observational clinical eye to diagnose the condition from its differentials, along with further research into treatment modalities to treat this condition.
Mehdi Ghahartars, Seyyede Zeinab Azimi, Mojgan Akbarzadeh Jahromi, Mohammad Reza Namazi   +3 more
wiley   +1 more source

The Paradox of Metachronous Lipoid Pneumonia

Respirology Case Reports, Volume 13, Issue 9, September 2025.
This is a case of recurrent exogenous lipoid pneumonia in a single patient caused by multiple unrelated substances. This case underscores the diagnostic value of radiologic patterns, the significance of meticulous exposure history, and the necessity of contemplating alternative aetiologies in patients with new infiltrates during cancer therapy ...
Haruki Kobayashi
wiley   +1 more source

Macrophages: Subtypes, Distribution, Polarization, Immunomodulatory Functions, and Therapeutics

MedComm, Volume 6, Issue 8, August 2025.
Macrophages originate from the yolk sac, fetal liver, and bone marrow, differentiating into two main subtypes: M1‐like (proinflammatory) and M2‐like (anti‐inflammatory). These subtypes exhibit high plasticity, allowing them to transform in response to environmental cues or therapeutic interventions.
Mengyuan Peng, Niannian Li, Hongbo Wang, Yaxu Li, Hui Liu, Yanhua Luo, Bao Lang, Weihang Zhang, Shilong Li, Liujun Tian, Bin Liu   +10 more
wiley   +1 more source

Lipoid Proteinosis: Case Report and Review Literature

Siriraj Medical Journal, 2014
Lipoid proteinosis is a rare autosomal recessive deposition disorder due to mutation in the extracellular matrix protein 1 gene. Until now, there were only 300 cases reported in literature. Moreover, case reports in Thailand are limited.
Charussri Leeyaphan
doaj  

Lipoid proteinosis: A case report

Journal of Dr. NTR University of Health Sciences, 2017
Lipoid proteinosis is a rare disorder, with only 300 cases reported in the medical literature. It is inherited as an autosomal recessive trait, characterized by the deposition of a hyaline material in the dermis and submucosal connective tissues ...
Ramakrishnan Bharathi, Santiago Gnanadeepam, Nallaiyan Parthiban, Arunkumar Kamalakaran   +3 more
doaj   +1 more source

Clinicopathological Challenge: Five Males Presenting With Progressive Skin Thickening and Hoarse Voices

International Journal of Dermatology, Volume 64, Issue 7, Page 1161-1163, July 2025.
ABSTRACT Five male patients, including four siblings and one unrelated child, presented with progressive hoarseness, waxy eyelid papules, mucosal thickening, and skin plaques. Histopathologic analysis revealed PAS‐positive perivascular hyaline deposition, and genetic testing confirmed a homozygous ECM1 mutation in all patients, consistent with lipoid ...
R. Maxwell Regester, Molly Antonson, Nicole N. Harter   +2 more
wiley   +1 more source

Lipoid proteinosis in two siblings

Indian Journal of Dermatology, 2006
Lipoid proteinosis denotes a rare autosomal recessive disorder. We report here lipoid proteinosis in a 31-year-old unmarried female along with her sibling.
Behera Samira Kumar, Nayak Surajit, Debi Basanti, Sahu Antaryami, Mishra Debiprasad   +4 more
doaj  

The Novel Use of Daratumumab in the Treatment of Refractory Autoimmune Pulmonary Alveolar Proteinosis

Respirology Case Reports, Volume 13, Issue 6, June 2025.
We present a case of refractory autoimmune pulmonary alveolar proteinosis (aPAP) successfully treated with Daratumumab, a novel CD‐38 monoclonal antibody (mAb). ABSTRACT Autoimmune pulmonary alveolar proteinosis (aPAP) is caused by circulating anti‐granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) auto‐antibodies that impair alveolar macrophage
April Strong, Ying Sun, David Pilcher, Zane Kaplan, Rob G. Stirling   +4 more
wiley   +1 more source

Evaluating the Use of iPSC‐Derived Models in Understanding the Pathogenesis of Childhood Interstitial Lung Disease

Pediatric Pulmonology, Volume 60, Issue 5, May 2025.
ABSTRACT Rationale Genetic testing has significantly improved the diagnosis of childhood interstitial lung diseases (chILD), which have long challenged clinicians due to their heterogeneity and poor characterization. It is now imperative to study variants of unknown significance (VUS) to identify pathogenic mutations to optimize diagnosis and screening
Swetha Jinson, Shivanthan Shanthikumar, Rhiannon B. Werder   +2 more
wiley   +1 more source

Periodic Table of Immunomodulatory Elements and Derived Two‐Dimensional Biomaterials

Advanced Science, Volume 12, Issue 6, February 10, 2025.
Two‐dimensional (2D) nanomaterials, possessing unique physiochemical properties, revolutionize the field of biomedical engineering to address critical diagnostic and therapeutic challenges. This review unveils the periodic table of 2D immunomodulatory elements, assessing synthesis, properties, immunomodulatory mechanisms and biocompatibility.
Alireza Rafieerad, Leena Regi Saleth, Soofia Khanahmadi, Ahmad Amiri, Keshav Narayan Alagarsamy, Sanjiv Dhingra   +5 more
wiley   +1 more source