Results 71 to 80 of about 164,679 (343)

Effects of β-Glucan Supplementation on LPS-Induced Endotoxemia in Horses

Animals
β-glucan is part of the cell wall of fungi and yeasts and has been known for decades to have immunomodulating effects on boosting immunity against various infections as a pathogen-associated molecular pattern that is able to modify biological responses ...
Milena Domingues Lacerenza, Júlia de Assis Arantes, Gustavo Morandini Reginato, Danielle Passarelli, Júlio César de Carvalho Balieiro, Andressa Rodrigues Amaral, Thiago Henrique Annibale Vendramini, Marcio Antonio Brunetto, Renata Gebara Sampaio Dória   +8 more
doaj   +1 more source

Anti-cytokine Storm Activity of Fraxin, Quercetin, and their Combination on Lipopolysaccharide-Induced Cytokine Storm in Mice: Implications in COVID-19 [PDF]

Iranian Journal of Medical Sciences
Background: Cytokine release syndrome (CRS) is the leading cause of mortality in advanced stages of coronavirus patients. This study examined the prophylactic effects of fraxin, quercetin, and a combination of fraxin+quercetin (FQ) on lipopolysaccharide ...
Nada Sahib Shaker, Hayder B Sahib, Nibras J Tahseen   +2 more
doaj   +1 more source

Madecassoside Protects Against LPS-Induced Acute Lung Injury via Inhibiting TLR4/NF-κB Activation and Blood-Air Barrier Permeability

Frontiers in Pharmacology, 2020
Madecassoside (MA), a crucial ingredient of Centella asiatica, has been reported to exhibit a variety of bioactivities, including antipulmonary fibrosis, and antiinflammatory effects.
Lu-Yuan Peng, Hai-Tao Shi, Meng Yuan, Jing-He Li, Ke Song, Jiang-Ni Huang, Peng-Fei Yi, Hai-Qing Shen, Ben-Dong Fu   +8 more
doaj   +1 more source

Exacerbation of Liver Tumor Metastasis in twist1a+/xmrk+ Double Transgenic Zebrafish following Lipopolysaccharide or Dextran Sulphate Sodium Exposure

Pharmaceuticals, 2021
The poor prognosis for patients with hepatocellular carcinoma (HCC) is related directly to metastasis. The Twist1 gene encodes for a transcription factor essential to embryogenesis.
Jeng-Wei Lu, Yuxi Sun, Liang-In Lin, Dong Liu, Zhiyuan Gong   +4 more
doaj   +1 more source

Diversity of O Antigens within the Genus Cronobacter: from Disorder to Order [PDF]

, 2015
Cronobacter species are Gram-negative opportunistic pathogens that can cause serious infections in neonates. The lipopolysaccharides (LPSs) that form part of the outer membrane of such bacteria are possibly related to the virulence of particular ...
Blažková, M, Forsythe, S, Fukal, L, Göselová, S, Javůrková, B, Karamonová, L, Ogrodzki, P, Schloss, PD, Vlach, J   +8 more
core   +1 more source

Relapsing–Remitting Multiple Sclerosis Is Associated With a Dysbiotic Oral Microbiome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by inflammation, demyelination, and neurological impairment. While the gut microbiota's role in MS is extensively studied, the association between the oral microbiota and MS remains underexplored, particularly in North American cohorts.
Sukirth M. Ganesan, Meeta Yadav, Sudeep Ghimire, Peter C. Lehman, Apurva J. Patel, Sydney Woods, Heena Olalde, Jemmie Hoang, Mishelle Paullus, Catherine Cherwin, Christine Gill, Tracey Cho, Ashutosh K. Mangalam   +12 more
wiley   +1 more source

Lipopolysaccharide (LPS, endotoxin) of Proteus bacteria-chemical structure, serological specificity and the role in pathogenicity [PDF]

, 2008
Lipopolysaccharides (LPS) of Gram-negative bacteria are composed of three regions: О-specific chain (OPS), the core oligosaccharide and lipid A. All three regions of Proteus LPS were studied. The differences in the structure of OPS serve as the basis
Różalski, Antoni
core  

Non-classical immunology. Meeting Report [PDF]

, 2001
This large annual immunology meeting covered a wide range of subjects from biochemical protein characterizations to cell biology and the study of complex disease pathologies.
Allen, RL
core   +1 more source

Amide‐Linked Local Anesthetics Alter Tumor Biology in a Complex Human Tissue Model of Non‐Small Cell Lung Adenocarcinoma

Advanced Biology, EarlyView.
Amide local anesthetics (LA) affect tumor burden in various preclinical studies, possibly via their anti‐inflammatory properties. However, a translation into clinical evidence is still lacking. The current study demonstrates that LA ‐ even at clinically relevant concentrations – exert a strong anti‐tumoral effect in a complex ex vivo model patient ...
Juliane Krömer, Sebastian Krämer, Ngoc Anh Hoang, Doreen Sittig, Isabella Metelmann, Uta‐Carolin Pietsch, Sebastian N. Stehr, Sonja Kallendrusch, Tobias Piegeler   +8 more
wiley   +1 more source

Heat Sepsis Precedes Heat Toxicity in the Pathophysiology of Heat Stroke—A New Paradigm on an Ancient Disease

Antioxidants, 2018
Heat stroke (HS) is an ancient illness dating back more than 2000 years and continues to be a health threat and to cause fatality during physical exertion, especially in military personnel, fire-fighters, athletes, and outdoor laborers.
Chin Leong Lim
doaj   +1 more source