Results 51 to 60 of about 125,833 (306)

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Lipooligosaccharides (LOS) of Neisseria gonorrhoeae and Neisseria meningitidis have components that are immunochemically similar to precursors of human blood group antigens. Carbohydrate sequence specificity of the mouse monoclonal antibodies that recognize crossreacting antigens on LOS and human erythrocytes. [PDF]

, 1988
We have used mouse mAbs, 3F11 and 06B4, that are specific for highly conserved epitopes of Neisseria gonorrhoeae lipooligosaccharides (LOS) to identify immunochemically similar structures on human erythrocytes. mAb 3F11 agglutinated erythrocytes from all
Griffiss, J, Macher, B, Mandrell, R
core  

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

Risks associated with endotoxins in feed additives produced by fermentation [PDF]

, 2016
Acknowledgements We thank Jordi Tarrés Call, who recorded the discussions and offered advice about procedures, and Nicole Reisinger and Gerd Schatzmayr, who provided valuable information about endotoxins in animal feeds. The Rowett Institute of Nutrition
Bampidis, Vasileios, Brantom, Paul G., Costa, Lucio G., Dierick, Noël, Gropp, Jürgen, Leng, Lubomir, Martelli, Giovanna, Renshaw, Derek W., Wallace, R. John   +8 more
core   +2 more sources

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Lectin-like bacteriocins from pseudomonas spp. utilise D-rhamnose containing lipopolysaccharide as a cellular receptor [PDF]

, 2014
Lectin-like bacteriocins consist of tandem monocot mannose-binding domains and display a genus-specific killing activity. Here we show that pyocin L1, a novel member of this family from Pseudomonas aeruginosa, targets susceptible strains of this species ...
A Hviid, A Molinaro, AC Graham, AD Vinion-Dubiel, AHA Parret, AHA Parret, AJ McCoy, Aleksander W. Roszak, AM Abdel-Mawgoud, AW Schuttelkopf, Brian Smith, C Kleanthous, C Manichanh, CL Brown, CL Ng, D Franke, D Walker, Daniel Walker, DI Svergun, E Cascales, E Kurimoto, EJM Van Damme, F Gorrec, F Long, G Gorkiewicz, G Hester, G Kurisu, GN Murshudov, GR Vasta, Guy Tran Van Nhieu, HL Rocchetta, Inokentijs Josts, J Henao-Mejia, J Qin, JAM Fyfe, JB Lyczak, Joel Milner, JS Lam, JU Scher, K Smith, K Zeth, Kai I. Waløen, KC Carroll, KH Caffall, L Holm, L Stewart, Laura C. McCaughey, M Ramm, M Rivera, M Shimokawa, M-F Incardona, MA Jacobs, MB Kozin, ME Spehlmann, MGK Ghequire, MGK Ghequire, MGK Ghequire, MJ Claesson, N Sharon, Nicholas P. Tucker, NR Chandra, Olwyn Byron, P Emsley, PD Adams, PV Konarev, R Grinter, R Grinter, RA Laskowski, Rhys Grinter, Richard J. Cogdell, S Mori, Sharon Kelly, SY Shaw, T Ogawa, Tom Evans, V Ovod, VB Chen, VV Ovod, VV Volkov, WF Vranken, Y Hao, Y Michel-Briand, YA Knirel   +82 more
core   +4 more sources

Effects of β-Glucan Supplementation on LPS-Induced Endotoxemia in Horses

Animals
β-glucan is part of the cell wall of fungi and yeasts and has been known for decades to have immunomodulating effects on boosting immunity against various infections as a pathogen-associated molecular pattern that is able to modify biological responses ...
Milena Domingues Lacerenza, Júlia de Assis Arantes, Gustavo Morandini Reginato, Danielle Passarelli, Júlio César de Carvalho Balieiro, Andressa Rodrigues Amaral, Thiago Henrique Annibale Vendramini, Marcio Antonio Brunetto, Renata Gebara Sampaio Dória   +8 more
doaj   +1 more source

Biomimetic Nanovaccine Integrating Dendritic Cell Exosomes with Tumor Cell Membranes for Sustained Prophylaxis Against Glioblastoma

Advanced Functional Materials, EarlyView.
We have developed DEX/GM, an all‐natural, personalizable hybrid vaccine designed by coating dendritic cell‐derived exosomes (DEX) onto tumor cell membranes (GM) for sustained prophylaxis against glioblastoma (GBM). ABSTRACT Glioblastoma (GBM), one of the most aggressive and lethal brain tumors, remains incurable with a poor clinical prognosis.
Shanshan Li, Dongya Zhang, Shiyu Wang, Changhe Pang, Meng Zheng, Bingyang Shi, Yan Zou   +6 more
wiley   +1 more source

Testing the relationship between gut permeability, elevation of systemic lipopolysaccharides and chronic disease : A thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy at Massey University, Manawatu, New Zealand [PDF]

, 2016
The aim of my thesis was to test whether an increase in the permeability of the gut is accompanied by an increase in the level of systemic lipopolysaccharides (LPS), also referred to as endotoxin.
Gnauck, Anne
core  

Systems Biology and Pangenome of Salmonella O-Antigens. [PDF]

, 2019
O-antigens are glycopolymers in lipopolysaccharides expressed on the cell surface of Gram-negative bacteria. Variability in the O-antigen structure constitutes the basis for the establishment of the serotyping schema. We pursued a two-pronged approach to
Kavvas, Erol, Machado, Henrique, Monk, Jonathan M, Palsson, Bernhard O, Seif, Yara   +4 more
core   +2 more sources