Results 1 to 10 of about 124,080 (260)

Decoy Receptors Regulation by Resveratrol in Lipopolysaccharide-Activated Microglia

open access: yesCells, 2023
Resveratrol is a polyphenol that acts as antioxidants do, protecting the body against diseases, such as diabetes, cancer, heart disease, and neurodegenerative disorders, such as Alzheimer’s (AD) and Parkinson’s diseases (PD).
Rosa Calvello   +5 more
doaj   +6 more sources

Resveratrol Prevents Lipopolysaccharide-Induced Cognitive Impairment in Rats through Regulation of Hippocampal Glua1-Containing AMPA Receptors [PDF]

open access: yesPharmaceutical Sciences, 2022
Background: Evidence suggests that dysregulation in AMPA-type glutamate receptors (AMPA-Rs) has been associated with the pathogenesis of Alzheimer’s disease (AD), especially during its early phase.
Mohammadmehdi Hassanzadeh-Taheri   +3 more
doaj   +1 more source

The effect of activated protein C in the experimental disseminated intravascular coagulation model formed by lipopolysaccharide infusion [PDF]

open access: yesActa Cirúrgica Brasileira, 2020
Purpose: In this experimental study, activated protein C (APC), which has anticoagulant, antithrombotic, profibrinolytic, anti-inflammatory and antiapoptotic properties, was used to prevent coagulopathy in a disseminated intravascular coagulation (DIC ...
Abdullah Şahin, Nazmi Özer
doaj   +1 more source

Lipopolysaccharide as Receptor for Rhizobium Phage 1P [PDF]

open access: yesJournal of General Microbiology, 1975
Bacterial andphage strains. Rhizobium trifolii strains 24SM, HR, 1524~~ and XSM were used in these experiments. Mutants HR and 15, resistant to phage IP, were derived from 24~~. The former was obtained by U.V. treatment, whereas the latter was a spontaneous mutant isolated by selection with phage IP. Phage IP propagated on R.
E, Zajac, R, Russa, Z, Lorkiewicz
openaire   +2 more sources

Lipopolysaccharide induces a downregulation of adiponectin receptors in-vitro and in-vivo [PDF]

open access: yesPeerJ, 2015
Background. Adipose tissue contributes to the inflammatory response through production of cytokines, recruitment of macrophages and modulation of the adiponectin system.
Alison Hall   +3 more
doaj   +2 more sources

Activation and Immune Regulation Mechanisms of PYHIN Family During Microbial Infection

open access: yesFrontiers in Microbiology, 2022
The innate immune system defenses against pathogen infections via patten-recognition receptors (PRRs). PRRs initiate immune responses by recognizing pathogen-associated molecular patterns (PAMPs), including peptidoglycan, lipopolysaccharide, and nucleic ...
Xiaojiao Fan   +5 more
doaj   +1 more source

TLR4 Is the Signaling but Not the Lipopolysaccharide Uptake Receptor [PDF]

open access: yesThe Journal of Immunology, 2004
Abstract TLR4 is the primary recognition molecule for inflammatory responses initiated by bacterial LPS (endotoxin). Internalization of endotoxin by various cell types is an important step for its removal and detoxification. Because of its role as an LPS-signaling receptor, TLR4 has been suggested to be involved in cellular LPS uptake
Stefan, Dunzendorfer   +3 more
openaire   +2 more sources

Genes, Receptors, Signals and Responses to Lipopolysaccharide Endotoxin [PDF]

open access: yesScandinavian Journal of Immunology, 2000
C3H/HeJ inbred mice have been very useful for identifying genetic elements responsible for endotoxin‐mediated responses. Depending on the type of assays employed, Tlr‐2, Tlr‐4 and Lps/Ran have been shown to be important in lipopolysaccharide (LPS)‐mediated responses. The concept of a single LPS gene being responsible for the genetic defect found in C3H/
P M, Wong, S W, Chugn, B M, Sultzer
openaire   +2 more sources

Reviewing and identifying amino acids of human, murine, canine and equine TLR4 / MD-2 receptor complexes conferring endotoxic innate immunity activation by LPS/lipid A, or antagonistic effects by Eritoran, in contrast to species-dependent modulation by lipid IVa

open access: yesComputational and Structural Biotechnology Journal, 2013
There is literature evidence gathered throughout the last two decades reflecting unexpected species differences concerning the immune response to lipid IVa which provides the opportunity to gain more detailed insight by the molecular modeling approach ...
Christian Alexander   +2 more
doaj   +3 more sources

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