Results 41 to 50 of about 733,256 (293)
Adipokinetic hormone enhances nodule formation and phenoloxidase activation in adult locusts injected with bacterial lipopolysaccharide [PDF]
Interactions between the locust endocrine and immune systems have been studied in vivo in relation to nodule formation and activation of the prophenoloxidase cascade in the haemolymph.
Opoku-Ware, K. +2 more
core +1 more source
Finding a Toll on the Route: The Fate of Osteoclast Progenitors After Toll-Like Receptor Activation
M-CSF and RANKL are two crucial cytokines stimulating differentiation of mature, bone resorbing, multinucleated osteoclasts from mononucleated progenitor cells in the monocyte/macrophage lineage.
Pedro P. C. Souza, Ulf H. Lerner
doaj +1 more source
Sepsis-induced selective loss of NMDA receptors modulates hippocampal neuropathology in surviving septic mice. [PDF]
Sepsis-induced neuroinflammation plays an important role in sepsis-related brain dysfunction. However, the molecules that are targeted during neuroinflammation resulting from sepsis-induced brain dysfunction remain unclear.
Shuibing Zhang +5 more
doaj +1 more source
Resistin competes with lipopolysaccharide for binding to toll‐like receptor 4 [PDF]
AbstractToll‐like receptors (TLRs) are a family of cellular structures activated by recognition of pathogen associated molecular sequences. The activation of TLRs triggers a variety of intracellular mechanisms aiming to protect the host from the invading microorganisms. Lipopolysaccharide (LPS) is the main ligand for TLR4. Here we show that resistin, a
Tarkowski, Andrej +3 more
openaire +2 more sources
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Calreticulin and Galectin-3 Opsonise Bacteria for Phagocytosis by Microglia
Opsonins are soluble, extracellular proteins, released by activated immune cells, and when bound to a target cell, can induce phagocytes to phagocytose the target cell. There are three known classes of opsonin: antibodies, complement factors and secreted
Tom O. J. Cockram +2 more
doaj +1 more source
Reversing Lipopolysaccharide Toxicity by Ligating the Macrophage Fcγ Receptors [PDF]
Abstract Our laboratory has previously demonstrated that the ligation of phagocytic receptors on macrophages can influence cytokine production. In this study, we examine the cytokine responses to multiple inflammatory stimuli following FcγR ligation. Macrophages were stimulated in vitro with LPS, lipoteichoic acid, CD40 ligand, or low
J S, Gerber, D M, Mosser
openaire +2 more sources
The role of toll-like receptors in the adrenal gland [PDF]
Sepsis is caused by infection and often followed by an overwhelming inflammatory response. This can lead to shock, organ failure and even death. Each year approximately 60,000 people die in Germany due to sepsis.
Tran, Thi Hoai Nguyen
core
Regulation of murine B cell development and function [PDF]
Vertebrates have developed an effective and protective, yet complex and dynamic immune system to defend themselves against the many threats from microorganisms.
Flück, Lukas Andreas
core +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source

