Results 101 to 110 of about 585,044 (300)

Epidemiological Study of Lipoprotein (a) in Okinawa [PDF]

, 1995
A study of serum levels of lipoprotein (a) (Lp (a)) was performed among 217 normal adults including 135 men and 82 women in the northern part of Okinawa. Ages of the subjects ranged from 24 to 76 with an average of 49 years.
Tamamoto, Tohru, Sakugawa, Hiroshi, Toda, Takayoshi, Yamasiro, Tetsu, Nagata, Junichi, Yamashiro, Akihiro   +5 more
core  

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

Advanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha, Ayushi Mairal, Shreya Mehrotra, Shiv K. Sarin, Ashok Kumar   +4 more
wiley   +1 more source

ApoA-I-Mediated Lipoprotein Remodeling Monitored with a Fluorescent Phospholipid

Biology, 2019
We describe simple, sensitive and robust methods to monitor lipoprotein remodeling and cholesterol and apolipoprotein exchange, using fluorescent Lissamine Rhodamine B head-group tagged phosphatidylethanolamine (*PE) as a lipoprotein reference marker ...
Edward B. Neufeld, Masaki Sato, Scott M. Gordon, Vinay Durbhakula, Nicolas Francone, Angel Aponte, Gizem Yilmaz, Denis Sviridov, Maureen Sampson, Jingrong Tang, Milton Pryor, Alan T. Remaley   +11 more
doaj   +1 more source

A rare cause of childhood-onset nephrotic syndrome: lipoprotein glomerulopathy

, 2014
We report on a 12-year-old female patient with lipoprotein glomerulopathy (LPG) who was proven to be heterozygous for ApoE2 Kyoto (Arg25Cys). Her family members have the same variant but do not have obvious signs of renal function impairment.
蔡宜蓉 ;林維洲 ;曹永魁, Liao, Min-Tser;Tsai, I-Jung;Cheng, Hui-Teng;Lin, Wei-Chou;Chang, Yen-Wen;Lin, Yi-Heng;Tsau, Yong-Kwei   +1 more
core   +1 more source

Introducing Borsantrazole: A Trifunctional Boron‐Based Pyrazole That Extends the Lifespan of Amyotrophic Lateral Sclerosis Mice

Advanced Science, EarlyView.
Herein we report a boron‐based pyrazole, (Borsantrazole ‐ a small molecule that selectively targets oxidative stress) that significantly increases survival, reduces weight loss, delays disease onset, and affects global protein changes in the SOD1‐G37R mouse model of ALS.
Nitesh Sanghai, Rhonda Kelley, Ying Lao, M. Immanuel Reyes Madlangsakay, Prasanta Paul, M. Alejandra Llanes‐Cuesta, Jun‐Feng Wang, René P. Zahedi, Jiming Kong, Geoffrey K. Tranmer   +9 more
wiley   +1 more source

Role of cholesteryl ester transfer protein in selective uptake of high density lipoprotein cholesteryl esters by adipocytes

Journal of Lipid Research, 2004
Previous reports attributed cholesteryl ester transfer protein (CETP)-mediated HDL cholesteryl ester (CE) selective uptake to the CETP-mediated transfer of CE from HDL to newly secreted apolipoprotein B-containing lipoproteins, which are then ...
Gerard Vassiliou, Ruth McPherson
doaj   +1 more source

High-Level Expression of Various Apolipoprotein (a) Isoforms by "Transferrinfection". The Role of Kringle IV Sequences in the Extracellular Association with Low-Density Lipoprotein [PDF]

, 1994
Characterization of the assembly of lipoprotein(a) [Lp(a)] is of fundamental importance to understanding the biosynthesis and metabolism of this atherogenic lipoprotein. Since no established cell lines exist that express Lp(a) or apolipoprotein(a) [apo(a)
Sasa Frank, Srdan Durovic, Frank, Sasa, Kurt Zatloukal, Krasznai, Krisztina, Lobentanz, Eva-Maria, Utermann, Gerd, Krisztina Krasznai, Eva-Maria Lobentanz, Kostner, Gert M., Wagner, Ernst, Ernst Wagner, Cotten, Matt, Hans Dieplinger, Zatloukal, Kurt, Kostner, Gerd M., Matt Cotten, Durovic, Srdan, Dieplinger, Hans, Gerd Utermann, Zechner, Rudolf   +20 more
core   +1 more source

HMGCR‐Driven Cholesterol Metabolism Promotes Osteoarthritis Progression by Accelerating Synovial Fibroblast Senescence

Advanced Science, EarlyView.
In the pathological context of osteoarthritis (OA), the phosphorylation of AKT1 at Ser473 enhances its binding to Lys140 of Insig1, which facilitates the formation of AKT1–Insig1 complex. Subsequently, the activation of AKT1 promotes the phosphorylation of Insig1 at Ser189, potentially enhancing the dissociation of Insig1 from sterol regulatory element‑
Xiaoqi Zhang, Siru Zhou, Xi Liu, Wei Xiang, Xiuqin Peng, Yu Tian, Song Li, Hailin Wang, Bo Liao, Shunzheng Fang, Runze Jin, Jinhui Wu, Chuanqing Bai, Wei Zhang, Bo Huang, Bingfei Li, Lifeng Chen, Lin Chen, Bin Zhang, Zhenhong Ni   +19 more
wiley   +1 more source

Apolipoprotein C-II Mimetic Peptide Promotes the Plasma Clearance of Triglyceride-Rich Lipid Emulsion and the Incorporation of Fatty Acids into Peripheral Tissues of Mice

Journal of Nutrition and Metabolism, 2019
Aim. Plasma apolipoprotein C-II (apoC-II) activates lipoprotein lipase (LPL) and thus lowers plasma triglycerides (TG). We previously reported that a human apoC-II mimetic peptide (C-II-a) decreased plasma TG in apoC-II mutant mice, as well as in apoE ...
Tomohiro Komatsu, Toshihiro Sakurai, Anna Wolska, Marcelo J. Amar, Akiko Sakurai, Boris L. Vaisman, Denis Sviridov, Stephen Demosky, Milton Pryor, Katsunori Ikewaki, Alan T. Remaley   +10 more
doaj   +1 more source

Influence of different fat emulsions with 10 or 20% MCT/LCT or LCT on lipoproteins in plasma of patients after abdominal surgery [PDF]

, 1998
In patients after elective abdominal surgery, different fat emulsions were used to compare their efficacy in total parenteral nutrition and in normalizing plasma lipoprotein levels.
Jauch, Karl-Walter, Wolfram, Günther, Hailer, Susanne, Hailer, Susanne;Jauch, Karl-Walter;Wolfram, Günther   +3 more
core   +1 more source