Results 81 to 90 of about 542,865 (315)
ZDHHC9‐Mediated Palmitoylation of ACSL4 Drives Ferroptosis in Diabetes Mellitus–Induced Erectile Dysfunction
Advanced Science, EarlyView.ABSTRACT
Diabetes mellitus‐induced erectile dysfunction (DMED) is a highly prevalent complication among diabetic patients; however, its underlying pathogenic mechanisms remain incompletely understood. Metabolic disorder is a hallmark of diabetes, yet its precise contribution to DMED progression is not well defined.Wanyang Guo, Ming Xiao, Mengjun Huang, Dongzi Peng, Ruijiang Zeng, Ruilin Liu, Yuanqiao Zhao, Zhihan Ouyang, Yulong Hong, Zexian Ding, Zhuo Xing, Hao Su, Jinxiang Wang, Wenjun Mao, Xin Jin +14 morewiley +1 more sourceLCAT protects against Lipoprotein‐X formation in a murine model of drug‐induced intrahepatic cholestasis
Pharmacology Research & Perspectives, 2020 Familial lecithin:cholesterol acyltransferase (LCAT) deficiency (FLD) is a rare genetic disease characterized by low HDL‐C levels, low plasma cholesterol esterification, and the formation of Lipoprotein‐X (Lp‐X), an abnormal cholesterol‐rich lipoprotein ...Marcelo J. A. Amar, Lita A. Freeman, Takafumi Nishida, Maureen L. Sampson, Milton Pryor, Boris L. Vaisman, Edward B. Neufeld, Sotirios K. Karathanasis, Alan T. Remaley +8 moredoaj +1 more sourceBiological, clinical and population relevance of 95 loci for blood lipids [PDF]
, 2010 Plasma concentrations of total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol and triglycerides are among the most important risk factors for coronary artery disease (CAD) and are targets for therapeutic ...J. Sinisalo, Döring, Angela, Boehnke, M., N. G. Martin, Silander, K, Ridker, P.M., P. Elliott, Lamina, C., Assimes, Themistocles L., L. L. Bonnycastle, Ingelsson, E., Kastelein, JJP, Ingelsson, E,, N. J. Wareham, Teslovich, T.M., Ejebe, K.G., Sanna, Serena, Hall, A.S. (Alistair), McCarthy, Mark I, Boerwinkle, E., Teslovich, Tanya M., Parker, A.N., Surakka, I., L. M. Rose, Hicks, Andrew A, Boekholdt, S Matthijs, James P. Pirruccello, Hengstenberg, Christian, Mangino, M., Ruokonen, A., Bandinelli, S, Toshiko Tanaka, Shin Cho, Y. (Yoon), Kim, Young Jin, A. S. Hall, Bonnycastle, LL, Sanna, S., Peloso, Gina M, Elena Gonzalez, Silander, K., Rose, LM, Uitterlinden, Andre G., Smith, AV, C. Hengstenberg, Shin Cho, Y., Kaprio, Jaakko, T. Y. Wong, Edmondson, Andrew C., Jin Kim, Y. (Young), Pare, G. (Guillaume), Go, MJ, Y. d. I, Kastelein, J.J.P. (John), Hastie, Nicholas D, Orho-Melander, M. (Marju), Rick Twee-Hee Ong, Johansen, C.T. (Christopher), Loos, Ruth J F, Kronenberg, F. (Florian), T. Tanaka, S. Kathiresan, Kim, K., Stefansson, K, Whitfield, JB, Willemsen, G.A.H.M. (Gonneke), Tai, E.S., O'Donnell, CJ, Johansson, Asa, Wichmann, H.E. (Heinz Erich), Altshuler, D., Shin Cho, Yoon, Seielstad, M, Kronenberg, Florian, Johansen, C.T., Zee, RYL, Montgomery, G.W., Rose, Lynda M, Hofman, A., Roberts, Robert, Igl, W., Harris, T.B. (Tamara), Haritunians, T. (Talin), Smith, Albert V, Jin Kim, Y, Launer, Lenore J, Ziegler, A, Quertermous, T., Waterworth, D. (Dawn), Seielstad, Mark, Smit, J.H., Jarvelin, Marjo-Riitta, Li, Mingyao, Munroe, PB, de Geus, E.J., Cupples, L.A. (Adrienne), C. T. Johansen, Voight, Benjamin F., J. S. Kooner, Mary F. Feitosa, Sijbrands, E.J.G.; id_orcid, Rose, L.M. (Lynda), de Geus, Eco J C, Kastelein, John JP, König, I.R. (Inke), Kirsten O. Kyvik, Gabriel, S.B., Bergman, R.N., Stacey B. Gabriel, Gonzalez, E, Gyllensten, Ulf,, Strachan, David P., Hall, AS, Salomaa, Veikko, Wilson, James G.; id_orcid, Bergman, Richard N., M. J. Caulfield, Markku S. Nieminen, Collins, Francis S, Tai, E.-Shyong, Wendy McArdle, Groop, L.C., Johnson, T, Ong, RTH, Ingelsson, Erik, Penninx, B.W.J.H., Rudan, I. (Igor), Freimer, N.B. (Nelson), X. Sim, Lori L. Bonnycastle, Edmondson, A.C., G. M. Peloso, Guillaume Lettre, O’Donnell, Christopher J., Uitterlinden, Andre G, Kiran Musunuru, K. Kim, de Geus, EJ, Smith, A.V. (Albert Vernon), D. C. Croteau Chonka, McCarthy, MI, Benjamin F. Voight, Kuzawa, Christopher W, Gyllensten, U., Pramstaller, P.P. (Peter Paul), Janssens, A.C., Zhang, W., Schlessinger, D. (David), Stylianou, IM, Burtt, Noel P., M. Li, Reilly, Muredach P., Vitart, Veronique, Crawford, G., Kaplan, L.M., Ruokonen, A. (Aimo), Johansson, Åsa,, Waterworth, Dawn M., Taylor Jr, Herman A., Park, Taesung, Stringham, Heather M., Martin, Nicholas G, Launer, L.J., Scuteri, Angelo, A. Johansson, Cupples, L.A., Lucas, Gavin, Edmondson, A.C. (Andrew), C. Langenberg, Lettre, G, Yurii S. Aulchenko, Chasman, Daniel I., A. B. Feranil, Christian Hengstenberg, Wright, A.F., Caulfield, M.J., Dominiczak, Anna F, Hastie, Nicholas D., Kooner, J.S., Magnusson, Patrik KE, Schunkert, H, Cho, YS, Jaakko Tuomilehto, Gieger, C. (Christian), Hegele, Robert A, Thompson, JR, U. Gyllensten, James G. Wilson, Sinisalo, J., Nickerson, D.A., Sijbrands, Eric JG, Sijbrands, EJG, Igi, Wilmar, Nicholas G. Martin, Wareham, N.J., Sabatti, Chiara, A. F. Wright, Christie M. Ballantyne, Mangino, M, Ulf Gyllensten, de Faire, Ulf, Kooner, Jaspal S, Li, XH, Peter P. Pramstaller, Saharinen, J, Sandhu, M.S. (Manjinder), M. S. Sandhu, Yuan, X., Erdmann, Jeanette, I. M. Heid, Nicholas J. Wareham, R. T. Ong, B. A. Oostra, Loos, Ruth J. F., Stringham, H.M. (Heather), Pare, G, Rader, D.J. (Daniel), Pedersen, Nancy L., Peloso, G.M. (Gina), Johannes H. Smit, Ida Surakka, Schadt, E.E., Duijn, C.M. van, Pedersen, Nancy L, M. Mangino, Loos, RJF, Hicks, Andrew A., Munroe, Patricia B., Havulinna, A.S. (Aki), Collins, F.S., Whitfield, J. (John), Scott, J, A. V. Smith, H. A. Taylor, Wilson, James F, Wilson, James G, L. Ferrucci, J. M. Ordovas, O'Donnell, C.J. (Christopher), Quertermous, Thomas, M. F. Feitosa, Gyllensten, Ulf, D. P. Strachan, Parker, AN, Ballantyne, C.M., Stringham, He.M., Ripatti, S., S. Bandinelli, Pedersen, N.L. (Nancy), Perola, Markus, Cristian Pattaro, Holm, Hilma, de Faire, U., Waterworth, DM, de Geus, EJC, Ruokonen, Aimo, Hottenga, JJ (Jouke Jan), Groop, Leif C, Erdmann, J, Alex N. Parker, Wright, AF, Aulchenko, Y.S., Hottenga, J.J., Musunuru, K., Lange, Leslie A., L. A. Lange, Toby Johnson, Twee-Hee Ong, R., Iris M. Heid, Kooner, J.S. (Jaspal), Cornelia M. van Duijn, Hicks, A.A., Musunuru, K, Smit, Johannes H, Sijbrands, EJ, Marroni, F. (Fabio), Feitosa, Mary F, Nancy L. Pedersen, Hua Zhao, Jing, Kim, Kyunga, Tai, E.-S., Bergman, RN, Waterworth, Dawn M, Hovingh, G Kees, Melander, O, Thorsteinsdottir, U, R. A. Hegele, Wilson, James; id_orcid, Jarvelin, MR, Ziegler, Andreas, A. Scuteri, Wright, A.F. (Alan), Jin Go, Min, Jing Hua Zhao, Igi, Wilmar,, Salomaa, V. (Veikko), van Duijn, Cornelia M., Hegele, R.A. (Robert), McArdle, W.L. (Wendy), Melander, O. (Olle), B. F. Voight, Vitart, V. (Veronique), Thorsteinsdottir, U. (Unnur), Luan, J., Rotter, J.I., Jarvelin, M.-R., Groop, L. (Leif), Lakatta, Edward G., Psaty, B.M. (Bruce), Gavin Lucas, Orho-Melander, Marju,, G. Kees Hovingh, Rudan, I., Groop, LC, A. S. Havulinna, Ejebe, KG, R. Laaksonen, U. d. Faire, Barroso, Ines, R. Roberts, Gabriel, Stacey B., Tim D. Spector, Collins, FS, Wilson, James F., Kathiresan, S. (Sekar), Kastelein, John J. P., Ruokonen, A, Wilson, James G., Stylianou, I.M., Gonzalez, E., Jin Kim, Young, Zhao, JH, Alan R. Tall, Oostra, Ben A, Kees Hovingh, G, Schlessinger, David, Pramstaller, PP, Lange, Leslie A, Döring, A. (Angela), Ingelsson, E, Vollenweider, P, J. C. M, Igl, W, Wilmar Igl, Janssens, A Cecile JW, Orho-Melander, M, Jaspal S. Kooner, Yuan, Xin, Ordovas, JM, Thomas Meitinger, Sijbrands, Eric J. G., Lamina, Claudia, Barroso, I.E. (Inês), Elliott, P., Li, X., N. L. Pedersen, Dawn M. Waterworth, R. J. F, Kuzawa, CW, Gonzalez, E. (Elena), L. A. Cupples, Kuzawa, Christopher W., N. D. Hastie, Claudia Lamina, Robert Y. L. Zee, Demissie, Serkalem, Luan, JA, McCarthy, M.I. (Mark), P. K. E, Altshuler, David, Aimo Ruokonen, Tanaka, T, Kim, YJ, Marjo-Riitta Jarvelin, Aulchenko, Y.S. (Yurii), C. Gieger, Francis S. Collins, Luan, Jian'an, M. S. Nieminen, Psaty, Bruce M., Stringham, Heather M, K. G. Ejebe, Kyunga Kim, Hegele, RA, Joshua D. Smith, Caulfield, Mark J., Tuomilehto, J., J. F. Wilson, Feitosa, MF, Gyllensten, U, U. Thorsteinsdottir, Taylor, Herman A, Munroe, Patricia B, John Chambers, D. J. Rader, L. Adrienne Cupples, I. R. König, Sandhu, Manjinder S., Robert Roberts, K. Musunuru, Deloukas, P, Guiducci, Candace, Laaksonen, R. (Reijo), J. I. Rotter, Ejebe, K.G. (Kenechi), G. R. Abecasis, Andrew A. Hicks, Luben, R.N. (Robert), Ordovas, J.M. (Jose), Bis, Joshua C, Andre G. Uitterlinden, Pirruccello, J.P., Crawford, G. (Gabe), Song, K. (Kijoung), D. Masson, Serena Sanna, Stylianou, Ioannis M, Doering, A, Lokki, ML, Lakatta, EG, Heid, I.M. (Iris), Salomaa, V., Bis, J.C. (Joshua), Smith, Joshua D, Uda, M, Magnusson, Patrik K. E., Chasman, D.I. (Daniel), Ejebe, Kenechi G., E. Ingelsson, Mohlke, K.L., Hall, Alistair S., Guiducci, C, Campbell, Harry, Panagiotis Deloukas, Barbalic, M., Song, K, Laaksonen, Reijo, Fouchier, S.W., Vollenweider, P., Lettre, G., Waeber, G. (Gérard), de Geus, Eco JC, Linda S. Adair, Chambers, John, Y. S. Aulchenko, P. P. Pramstaller, Voight, Benjamin F, Scott, J., Collins, F.S. (Francis), Guo, X., Xin Yuan, C. M. van, Leena Peltonen, Magnusson, Patrik K E, Feitosa, M.F. (Mary Furlan), Rotter, J.I. (Jerome), Zee, Robert YL, L. S. Adair, Meitinger, T., Jacqueline C. M. Witteman, Penninx, BW, Jeanette Erdmann, Kari Stefansson, Kaprio, J., Åsa Johansson, Masson, D., Scott, J. (James), Lange, LA, Khaw, KT, Hottenga, J.J. (Jouke Jan), Albert V. Smith, Smith, A.V., Paul M Ridker, Gonçalo R. Abecasis, Mohlke, K.L. (Karen), Ripatti, S, Groop, Leif C., Hengstenberg, C, David P. Strachan, Burtt, N.P., Wilson, J.G., Erdmann, J. (Jeanette), Wareham, Nicholas J, Chasman, DI, Döring, A., Alan B. Feranil, Barroso, I., Boekholdt, S. Matthijs, Xiaohui Li, Nicholas D. Hastie, Vilmundur Gudnason, Doering, Angela, Cristen J. Willer, Thompson, J.R., Schadt, E.E. (Eric), Heid, Iris M, Li, M., Hegele, R.A., Pedersen, N.L., Bis, J.C., Wilson, J.F., Yii-der I. Chen, Guiducci, C. (Candace), D. Schlessinger, Samani, N.J., Kaplan, LM, G. Thorleifsson, Kathiresan, S, Rader, Daniel J., Jarvelin, M.-R. (Marjo-Riitta), Herman A. Taylor Jr, Pedersen, NL, T. Johnson, J. Hottenga, Saharinen, J. (Juha), Penninx, Brenda W. J. H., Willer, C.J. (Cristen), Li, MY, Wong, Tien Y, Soranzo, N., Peltonen, Leena, Dominiczak, A.F., Adair, LS, Waeber, G., Li, M, Boehnke, Michael, Rieder, M. (Mark), Perola, M. (Markus), Lenore J. Launer, Campbell, H., Wichmann, HE, Scott, James, Freimer, N.B., Isaacs, A., Heather M. Stringham, Luben, R, Pirruccello, JP, Pichler, Irene, Mark I. McCarthy, Alistair S. Hall, Silander, Kaisa, Y. J. Kim, Smit, Johannes H., Masson, D. (David), Boerwinkle, E.A. (Eric), Thompson, J.R. (John), Hovingh, G. Kees, Kaprio, J, Marroni, F, Pattaro, C., Bis, Joshua C., Kaprio, J. (Jaakko), Tanaka, T. (Toshiko), Peloso, G.M., Candace Guiducci, Tall, A.R. (Alan), Feranil, Al.B., Dominiczak, Anna F., Magnusson, P.K. (Patrik), Pattaro, Cristian, C. Hayward, Li, X, Young Jin Kim, J. Erdmann, Pattaro, C, C. Guiducci, Guo, X. (Xiuqing), David Schlessinger, Abecasis, Gonçalo R, Bandinelli, S. (Stefania), Hottenga, JJ, Cupples, L Adrienne, Hilma Holm, Saharinen, Juha, Aulchenko, Yurii S., Cupples, L. Adrienne, Kastelein, J.J.P., Pirruccello, J.P. (James), E. J. C, Veikko Salomaa, Lakatta, Edward G, de Geus, E.J.C., H. M. Stringham, J. Scott, Dorret I. Boomsma, Willemsen, G.; id_orcid, Khaw, Kay-Tee, Montgomery, Grant W, Sijbrands, E.J.G. (Eric), Zee, Robert Y L, J. J. P, Holm, H, Kastelein, John J.P., Roberts, R., Teslovich, TM, Stefansson, Kari, Peltonen, L. (Leena Johanna), M. Seielstad, Sekar Kathiresan, Samani, Nilesh J, V. Mooser, Rose, L.M., Spector, T.D. (Timothy), Kaisa Silander, Smith, Joshua D., Boomsma, Dorret I., Lange, L.A. (Leslie), Melander, O., Vollenweider, Peter, A. G. Uitterlinden, I. Surakka, Wong, T.Y., G. K. Hovingh, Soranzo, Nicole, A. C. J, Hayward, Caroline, Hofman, A. (Albert), Zhao, J.H. (Jing Hua), Albert Hofman, H. Wichmann, Voight, B.F., Elliott, P, Voight, B.F. (Benjamin), Igl, Wilmar, Ordovas, Jose M, B. W. J, Kaplan, Lee M, Willer, Cristen J, Gieger, Christian, König, Inke R., Geus, E.J.C. (Eco) de, Patrik K. E. Magnusson, Tanya M. Teslovich, Sim, X., Johansson, Å., Caulfield, MJ, Dominiczak, AF, Stylianou, Ioannis M., Brenda W. J. H. Penninx, Bonnycastle, L.L., Gabriel Crawford, Haritunians, T., I. Barroso, Gabriel, S.B. (Stacey), Loos, RJ, Kooner, Jaspal S., Jin Go, M. (Min), C. M. Ballantyne, Kooner, JS, Lamina, C, Hicks, AA, Roberts, R. (Robert), Krauss, Ronald M, Thorleifsson, Gudmar, J. B. Whitfield, H. Schunkert, Pirruccello, James P., Orho-Melander, M., Lakatta, E.G., Janssens, A. Cecile J. W., Oostra, B.A., Luan, J, Christian Gieger, Krauss, R.M. (Ronald), Cecile, A. (A.), S. B. Gabriel, Heribert Schunkert, Magnusson, P.K.E., Nickerson, Deborah A, Aki S. Havulinna, Bergman, Richard N, Hayward, C. (Caroline), Oostra, Ben, Chen, YD, Ingrid B. Borecki, P. B. Munroe, Lynda M. Rose, Daniel J. Rader, Song, Kijoung, Michael Boehnke, Hottenga, Jouke-Jan, Schunkert, Heribert, Spector, T.D., Sijbrands, E.J., Loos, R.J.F., Hall, Alistair S, Lange, L.A., Isaacs, Aaron, Christopher W. Kuzawa, G. W. Montgomery, Haritunians, T, Wilson, JG, Kathiresan, Sekar, Wilson, JF, Waeber, G, Masahiro Koseki, D. Altshuler, Tai, E-Shyong, Aulchenko, Yurii S, D. A. Nickerson, Markus Perola, Loos, R.J., G. Willemsen, Perola, M., Inke R. König, Penninx, B.W.J.H. (Brenda), Zee, R.Y., de Geus, Eco J. C., Ballantyne, CM, Holm, H., Lamina, C. (Claudia), X. Li, Sanna, S. (Serena), Tien Y. Wong, I. B. Borecki, Chasman, D.I., J. Saharinen, A. Ruokonen, Karen L. Mohlke, Sandhu, M.S., Musunuru, Kiran, Borecki, I.B., Adair, Linda S, Johnson, T. (Toby), Wilson, J.F. (James), Fouchier, Sigrid W, Wong, TY, Meitinger, T. (Thomas), Dominiczak, A. (Anna), Kenechi G. Ejebe, Ripatti, Samuli, McPherson, R., Deloukas, P. (Panagiotis), E. J. G, Y. S. Cho, Masson, David, Lucas, G., Langenberg, C. (Claudia), Chen, Yii-der I., Lee, JY, Tuomilehto, Jaakko, Ridker, Paul M., A. Isaacs, Ioannis M. Stylianou, Ricketts, S.L., Kronenberg, F, Ulf de Faire, Uda, M., Laaksonen, R, Samani, NJ, Freimer, Nelson B, Witteman, JC, Ballantyne, C. (Christie), Wong, Tien Y., V. Gudnason, Demissie, S, Harris, Tamara B, M. Koseki, X. Guo, Kathiresan, S., Mark Rieder, Montgomery, G.W. (Grant), Kijoung Song, Hegele, Robert A., Jin Kim, Y., D. M. Waterworth, Kyvik, KO, Campbell, H. (Harry), Taylor Jr., H.A., Caulfield, M. (Mark), L. J. Launer, Sandhu, MS, Boehnke, M, Ruth J. F. Loos, Sanna, S, H.-Erich Wichmann, Wichmann, H.-E., Elliott, Paul, Hua Zhao, J., Freimer, NB, Johansen, Christopher T., J. Lee, Peltonen, L, M. Lokki, Wright, Alan, Borecki, IB, König, Inke R, Hottenga, J.-J., Langenberg, C, Yuan, X. (Xin), Taylor, Herman A., Jr., Melander, Olle,, Borecki, Ingrid B., Peter Vollenweider, Ziegler, A., Assimes, T.L. (Themistocles), T. M. Teslovich, Yoon Shin Cho, Ben A. Oostra, J. D. Smith, E. E. Schadt, Manuela Uda, Serkalem Demissie, Stylianou, I.M. (Ioannis), Thorleifsson, G. (Gudmar), Gonzalez, Elena, Boerwinkle, Eric, Schadt, EE, Ejebe, Kenechi G, Parker, A.N. (Alex), Koseki, M. (Masahiro), Christopher T. Johansen, Wichmann, H.E., Zee, R.Y.L., Heid, I.M., Zhang, W, Boerwinkle, E, Mooser, Vincent, Uitterlinden, AG, Bis, JC, Lettre, Guillaume, Bandinelli, S., Krauss, Ronald M., Nickerson, D.A. (Deborah), Taylor, HA, Manjinder S. Sandhu, Gieger, C, Gabriel, Stacey B, Kuzawa, C.W., Tai, ES, Laaksonen, R., Min Jin Go, Gérard Waeber, Tamara B. Harris, Cecile J. W. Janssens, A., Khaw, K-T. (Kay-Tee), Surakka, Ida, Wichmann, H-Erich, M. Barbalic, Twee-Hee Ong, Rick, Xueling Sim, Unnur Thorsteinsdottir, Nelson B. Freimer, Croteau-Chonka, Damien C, Wright, Alan F, Schlessinger, D., Twee-Hee Ong, R. (Rick), Robert Luben, Guillaume Pare, Silander, K. (Kaisa), Damien C. Croteau-Chonka, H. Campbell, Mark J. Caulfield, Croteau-Chonka, DC, van Duijn, CM, Lee, J.Y., Jerome I. Rotter, Fouchier, Sigrid W., Schadt, Eric E., Kyvik, Kirsten O; id_orcid, F. S. Collins, K. L. Mohlke, Havulinna, Aki S., Marju Orho-Melander, Campbell, Harry; id_orcid, I. Rudan, Freimer, Nelson B., Jarvelin, M.R., Ferrucci, L. (Luigi), Chasman, Daniel I, A. Cecile J. W. Janssens, Havulinna, A.S., Nieminen, MS, Martin, NG, A. F. Dominiczak, Pirruccello, James P, Johnson, T., Munroe, P. (Patricia), Salomaa, V, Zhao, Jing Hua, Sabatti, C. (Chiara), Jose M. Ordovas, Florian Kronenberg, C. Lamina, Perola, M, Zwart, J-A. (John-Anker), Duijn, Cornelia, Marroni, Fabio, Witteman, Jacqueline C M, Kaplan, Lee M., Ronald M. Krauss, Borecki, Ingrid B, Croteau-Chonka, D.C., Rieder, M., Altshuler, D. (David), Ordovas, J.M., Soranzo, N. (Nicole), Eco J. C. de Geus, Kaplan, R.C. (Robert), Magnusson, PK, S. W. Fouchier, Mark Seielstad, Uda, Manuela, Guo, Xiuqing, Bandinelli, Stefania, X. Yuan, Krauss, RM, Parker, Alex N., K. Khaw, Sigrid W. Fouchier, Jian’an Luan, Pichler, I, Teslovich, Tanya M, A. N. Parker, Launer, Lenore J., Chambers, J. (John), Daniel I. Chasman, Loos, R.J.F. (Ruth), Ballantyne, Christie M, Kronenberg, F., Wareham, N.J. (Nick), Adair, L.S., Nieminen, Markku S, Igi, W, Marja-Liisa Lokki, Koenig, Inke R., M. J. Go, Scuteri, A., Gudnason, V. (Vilmundur), Abecasis, G.R., Luan, Jian’an, Boekholdt, S.M., Hengstenberg, C. (Christian), Schunkert, H., W. Igl, Reilly, M.P. (Muredach), Rotter, Jerome I, Tuomilehto, J. (Jaakko), Alan F. Wright, Claudia Langenberg, Thompson, John R, Whitfield, John B, Penninx, BWJH, McPherson, R. (Ruth), Stringham, H.M., Andreas Ziegler, Fouchier, SW, Vincent Mooser, Thompson, John R., Janssens, Cecile, N. J. Samani, J. H. Zhao, Lokki, Marja-Liisa, Lee, J.-Y., Themistocles L. Assimes, Erdmann, J., Ferrucci, L, Rader, Daniel J, Kyvik, K.O. (Kirsten Ohm), van Duijn, C.M., A. A. Hicks, Parker, Alex N, J. Chambers, Uitterlinden, A.G. (André), Penninx, Brenda WJH, Peloso, Gina M., S. M. Boekholdt, Lund University., Peloso, GM, Lee, J.Y. (Jong Young), Ridker, PM, R. Luben, Lucas, G. (Gavin), Luigi Ferrucci, N. Soranzo, McPherson, R, Paul Elliott, Kaplan, L. M., Reilly, MP, John B. Whitfield, Willer, C.J., G. Waeber, Gudnason, V, Deloukas, P., J. G. Wilson, Yuan, X, E. G. Lakatta, Mooser, V. (Vincent), Jin Go, M., Isaacs, A.J. (Aaron), Li, Xiaohui, Ordovas, Jose M., Muredach P. Reilly, J. P. Pirruccello, Zee, Robert Y. L., Haritunians, Talin, Robert A. Hegele, Edmondson, AC, Cupples, LA, A. C. Edmondson, James Scott +999 morecore +1 more sourceCanagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner
Advanced Science, EarlyView.Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.Wei Zhang, Yi Song, Changkun Li, Yuanyuan Luo, Mingwei Shao, Feng Guo, Fangyi Wei, Xunjie Fan, Wenwen Guo, Fengmei Xu, Yanhong Sang, Dongming Zhang, Yanhong Zhou, Lianwei Wang, Zhiqiang Kang, Yingjun Yang, Chunhua Song, Yanxia Liu, Xiaojun Ma, Jiao Wang, Chong Li, Shengnan Ma, Lin Zhao, Zhi Qin, Guolan Xing, Qiubo Zhao, Jun Li, Shumin Song, Dan Zhao, Ting Huang, Qingzhu Wang, Yanyan Zhao, Guijun Qin +32 morewiley +1 more sourceNanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis
Advanced Science, EarlyView.Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.Muhua Yu, Hongjie Dai, Xiaocui Zhong, Qibin Li, Hui Yuan, Yang Yang, Daiyong Huang, Lei Zhang, Rui Ran, Tian He, Yuanzhi Huang, Silas Villas‐Boas, Sergey Tumanov, Richard D. Cannon, Boris Novakovic, Richard Saffery, Yuhao Zhang, Xiaojing Dong, Ting‐Li Han +18 morewiley +1 more source
