Results 11 to 20 of about 542,865 (315)

Peroxisome Proliferator Activated Receptors and Lipoprotein Metabolism [PDF]

, 2008
Plasma lipoproteins are responsible for carrying triglycerides and cholesterol in the blood and ensuring their delivery to target organs. Regulation of lipoprotein metabolism takes place at numerous levels including via changes in gene transcription.
Kersten, A.H., Sander Kersten
core   +1 more source

HIV infection significantly reduces lipoprotein lipase which remains low after 6 months of antiretroviral therapy [PDF]

, 2008
Purpose of the study Fractional clearance rate of apolipoprotein B100-containing lipoproteins is reduced in HIV infection before and after antiretroviral (ARV) treatment [1].
LL Gathercole, M Boothby, S Das, Gathercole, L. L., McGee, K. C. (Kirsty Claire), Tomlinson, Jeremy, Shojaee-Moradie, F, Das, S. (Satyajit), Umpleby, AM, Tomlinson, J. W., Boothby, M., Umpleby, A.M., Shojaee-Moradie, F., F Shojaee-Moradie, JW Tomlinson, K McGee, Boothby, M, M Shahmanesh, Umpleby, A. M., Gathercole, LL, McGee, K, Das, S., Shahmanesh, Mohsen, Tomlinson, JW, Shahmanesh, M, AM Umpleby, Das, S   +26 more
core   +1 more source

Mathematical model for low density lipoprotein (LDL) endocytosis by hepatocytes [PDF]

, 2008
Individuals with elevated levels of plasma low density lipoprotein (LDL) cholesterol (LDL-C) are considered to be at risk of developing coronary heart disease.
B. O’Malley, J. A. D. Wattis, Panovska, J., Byrne, H.M., Jackson, K.G., H. Blackburn, Wattis, JA, H. M. Byrne, L. Pickersgill, O'Malley, B, Panovska, J, Wattis, J.A.D., Pickersgill, L, Pickersgill, L., Blackburn, H, Byrne, HM, Byrne, Helen, K. G. Jackson, Wattis, JAD, O'Malley, B., Blackburn, H., Jackson, KG, J. Panovska   +22 more
core   +1 more source

Adipose tissue cholesteryl ester transfer protein mRNA in response to probucol treatment: cholesterol and species dependence

Journal of Lipid Research, 1993
Probucol treatment results in an increase in plasma concentrations of cholesteryl ester transfer protein (CETP) which may account, in part, for the effects of this agent on plasma concentrations of HDL cholesterol. We have examined the mechanism by which
EM Quinet, P Huerta, D Nancoo, AR Tall, YL Marcel, R McPherson   +5 more
doaj   +1 more source

Lipoproteins and lipoprotein metabolism in periodontal disease [PDF]

Clinical Lipidology, 2010
A growing body of evidence indicates that the incidence of atherosclerosis is increased in subjects with periodontitis - a chronic infection of the oral cavity. This article summarizes the evidence that suggests periodontitis shifts the lipoprotein profile to be more proatherogenic.
Rachel, Griffiths, Suzanne, Barbour
openaire   +2 more sources

Secretion of biologically active human proapolipoprotein A-I in a baculovirus-insect cell system: protection from degradation by protease inhibitors

Journal of Lipid Research, 1995
Studies of the structure and function of apolipoprotein A-I (apoA-I) often require its purification by delipidation of high density lipoprotein isolated from large quantities of human plasma and separation of apoA-I from other plasma apolipoproteins.
L E Pyle, P Barton, Y Fujiwara, A Mitchell, N Fidge   +4 more
doaj   +1 more source

Bacterial expression and site-directed mutagenesis of a functional recombinant apolipoprotein.

Journal of Lipid Research, 1995
To facilitate structure-function studies of Manduca sexta apolipophorin III (apoLp-III), its nucleotide coding sequence was cloned from a fat body cDNA library by in vitro DNA amplification.
R O Ryan, D Schieve, M Wientzek, V Narayanaswami, K Oikawa, C M Kay, L B Agellon   +6 more
doaj   +1 more source

Lipoprotein apheresis to treat elevated lipoprotein (a) [PDF]

Journal of Lipid Research, 2016
An elevated plasma concentration of lipoprotein (a) [Lp(a)] is an independent risk factor for cardiovascular disease. Life style modification and currently available drugs either fail to effectively lower plasma Lp(a) levels or do not result in clinical benefit. However, lipoprotein apheresis is very efficient in decreasing Lp(a) concentrations.
Elisa, Waldmann, Klaus G, Parhofer
openaire   +2 more sources

Platelet interaction with bioactive lipids formed by mild oxidation of low-density lipoprotein [PDF]

, 2006
Oxidation of low-density lipoprotein (LDL) generates pro-inflammatory and pro-thrombotic mediators that play a crucial role in cardiovascular and inflammatory diseases.
Wolfgang Siess, Siess, Wolfgang
core   +1 more source

Quantitation of plasma mevalonic acid using gas chromatography-electron capture mass spectrometry.

Journal of Lipid Research, 1991
Circulating concentrations of mevalonic acid (MVA) change in parallel with, and may be used as a marker of cholesterol biosynthesis. Plasma MVA levels have been quantified using a sensitive and specific capillary gas chromatography-electron capture mass ...
A Scoppola, VM Maher, GR Thompson, NB Rendell, GW Taylor   +4 more
doaj   +1 more source