Results 21 to 30 of about 585,044 (300)

Bacterial expression and site-directed mutagenesis of a functional recombinant apolipoprotein.

Journal of Lipid Research, 1995
To facilitate structure-function studies of Manduca sexta apolipophorin III (apoLp-III), its nucleotide coding sequence was cloned from a fat body cDNA library by in vitro DNA amplification.
R O Ryan, D Schieve, M Wientzek, V Narayanaswami, K Oikawa, C M Kay, L B Agellon   +6 more
doaj   +1 more source

Quantitation of plasma mevalonic acid using gas chromatography-electron capture mass spectrometry.

Journal of Lipid Research, 1991
Circulating concentrations of mevalonic acid (MVA) change in parallel with, and may be used as a marker of cholesterol biosynthesis. Plasma MVA levels have been quantified using a sensitive and specific capillary gas chromatography-electron capture mass ...
A Scoppola, VM Maher, GR Thompson, NB Rendell, GW Taylor   +4 more
doaj   +1 more source

Lipoproteins and lipoprotein metabolism in periodontal disease [PDF]

Clinical Lipidology, 2010
A growing body of evidence indicates that the incidence of atherosclerosis is increased in subjects with periodontitis - a chronic infection of the oral cavity. This article summarizes the evidence that suggests periodontitis shifts the lipoprotein profile to be more proatherogenic.
Rachel, Griffiths, Suzanne, Barbour
openaire   +2 more sources

Platelet interaction with bioactive lipids formed by mild oxidation of low-density lipoprotein [PDF]

, 2006
Oxidation of low-density lipoprotein (LDL) generates pro-inflammatory and pro-thrombotic mediators that play a crucial role in cardiovascular and inflammatory diseases.
Wolfgang Siess, Siess, Wolfgang
core   +1 more source

Apolipoprotein distribution in human lipoproteins separated by polyacrylamide gradient gel electrophoresis.

Journal of Lipid Research, 1988
The heterogeneity of serum lipoproteins (excluding very low density (VLDL) and intermediate density (IDL) lipoproteins) and that of lipoproteins secreted by HepG2 cells has been studied by immunoblot analysis of the apolipoprotein composition of the ...
C A Vézina, R W Milne, P K Weech, Y L Marcel   +3 more
doaj   +1 more source

Characterization of mutations in the low density lipoprotein (LDL)-receptor gene in patients with homozygous familial hypercholesterolemia, and frequency of these mutations in FH patients in the United Kingdom

Journal of Lipid Research, 1996
Mutations in the gene for the low density lipoprotein (LDL) receptor have been identified in 15 patients with homozygous familial hypercholesterolemia (FH).
J C Webb, X M Sun, S N McCarthy, C Neuwirth, G R Thompson, B L Knight, A K Soutar   +6 more
doaj   +1 more source

The physiopathology of lipoprotein a

Frontiers in Bioscience, 2010
Lipoprotein(a) (also called Lp(a)) is a lipoprotein subclass. Different studies have identified Lp(a) as a putative risk factor for atherosclerotic diseases such as coronary artery disease and stroke. The physiological role of Lp(a) in humans is still unclear, but it seems that individuals with low concentrations of plasma Lp(a) manifest no deficiency ...
GALVANO, Fabio, MALAGUARNERA M, VACANTE M, MOTTA, Massimo, RUSSO C, MALAGUARNERA M, D'ORAZIO N, MALAGUARNERA, Lucia   +7 more
openaire   +3 more sources

Phosphatidylcholine biosynthesis is required for secretion of truncated apolipoprotein Bs from McArdle RH7777 cells only when a neutral lipid core is formed

Journal of Lipid Research, 1997
Decreased phosphatidylcholine biosynthesis inhibits the secretion of very low density lipoproteins from hepatocytes (Yao, Z. and D. E. Vance. 1988. J. Biol. Chem. 263: 2998-3004).
P S Vermeulen, S Lingrell, Z Yao, D E Vance   +3 more
doaj   +1 more source

Expression and secretion of rabbit plasma cholesteryl ester transfer protein by Pichia pastoris

Journal of Lipid Research, 1996
The rabbit cholesteryl ester transfer protein (CETP) was expressed in the methylotrophic yeast Pichia pastoris by introducing the CETP cDNA under the control of the methanol-inducible alcohol oxidase promoter.
H Kotake, Q Li, T Ohnishi, K W Ko, L B Agellon, S Yokoyama   +5 more
doaj   +1 more source

Nonimmunochemical quantitation of mammalian apolipoprotein A-I in whole serum or plasma by nonreducing gel electrophoresis.

Journal of Lipid Research, 1989
A rapid and convenient method for the quantitation of mammalian apoA-I has been developed. The method involves nonreducing sodium dodecyl sulfate gel electrophoresis and Coomassie blue staining, and takes advantage of the relative abundance of apoA-I in ...
D S France, T E Hughes, R Miserendino, J A Spirito, J Babiak, J B Eskesen, C Tapparelli, J R Paterniti, Jr   +7 more
doaj   +1 more source