Results 191 to 200 of about 840,133 (341)

The Relationship of Dietary Cholesterol with Serum Low-Density Lipoprotein Cholesterol and Confounding by Reverse Causality: The INTERLIPID Study

open access: diamond, 2018
Yukiko Okami   +13 more
openalex   +2 more sources

Chronic PET‐Microplastic Exposure: Disruption of Gut–Liver Homeostasis and Risk of Hepatic Steatosis

open access: yesAdvanced Science, EarlyView.
Chronic exposure to environmentally relevant PET microplastics disrupts gut–liver homeostasis, leading to hepatic steatosis, early fibrosis, and altered gut microbiota. These effects signal metabolic imbalance and gut–liver axis impairment, emphasizing chronic microplastic ingestion as an emerging environmental health risk linked to non‐communicable ...
Surye Park   +5 more
wiley   +1 more source

Serum amyloid A does not affect high-density lipoprotein cholesterol measurement by a homogeneous assay

open access: hybrid, 2018
Megumi Sato   +9 more
openalex   +1 more source

Payload‐Driven Design of Polymeric Carriers for Nucleic Acid Delivery: Insights from Structure–Function Relationships

open access: yesAdvanced Science, EarlyView.
Polymeric carriers provide versatile platforms for nucleic acid delivery. This review introduces a novel perspective inspired by protein structural organization to explore structure–function relationships of polymeric carriers, highlighting requirements of different nucleic acid payloads.
Hanieh Moradian   +3 more
wiley   +1 more source

SP282DIFFERENCES IN LIPOPROTEINS SUBFRACTIONS BETWEEN PATIENTS WITH CAD AND CAD PLUS CKD [PDF]

open access: bronze, 2017
Jacek Rysz   +3 more
openalex   +1 more source

Targeting Endothelial KDM5A to Attenuate Aging and Ameliorate Age‐Associated Metabolic Abnormalities

open access: yesAdvanced Science, EarlyView.
This study identifies endothelial KDM5A as a key regulator of aging. KDM5A deficiency accelerates aging by enhancing H3K4me3‐mediated FABP4 expression, disrupting fatty acid metabolism, and promoting multi‐organ senescence. KDM5A restoration or FABP4 inhibition reverses these adverse effects and extends lifespan, positioning the KDM5A/FABP4 axis as a ...
Rifeng Gao   +21 more
wiley   +1 more source

Genetically‐Programmed Hypervesiculation of Lactiplantibacillus Plantarum Increases Production of Bacterial Extracellular Vesicles with Therapeutic Efficacy in a Preclinical Inflammatory Bowel Disease Model

open access: yesAdvanced Science, EarlyView.
The development of a novel engineered strain of Lactiplantibacillus plantarum (Lp) is reported that can produce bacterial extracellular vesicles (BEVs) at >60‐fold higher yields than the unmodified parental strain. These Lp BEVs retain therapeutic bioactivity as validated in a mouse model of dextran sodium sulfate‐induced colitis.
Nicholas H Pirolli   +16 more
wiley   +1 more source

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