Results 261 to 270 of about 849,886 (339)

Multi‐omic profiling reveals immune cell priming signature linked to lupus prognosis

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Systemic lupus erythematosus (SLE) is a multi‐organ disease with widespread immune dysregulation and significant unmet clinical need. Blood‐based gene expression studies have advanced our understanding of SLE pathogenesis but may overlook critical tissue‐specific mechanisms that drive disease heterogeneity and progression.
Michael A. Smith   +23 more
wiley   +1 more source

TWEAK/Fn14 signaling drives oxidative cardiac injury in systemic lupus erythematosus: Evidence from patient biomarker studies, lupus mouse models, and cardiomyocyte assays

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Cardiac involvement is a major cause of morbidity in systemic lupus erythematosus (SLE). Tumor necrosis factor–like weak inducer of apoptosis (TWEAK) is elevated in SLE, but its contribution to lupus‐associated cardiac injury is unclear. We investigated the role of TWEAK/Fn14 signaling in SLE‐related cardiomyopathy and its potential as a ...
Yale Liu   +12 more
wiley   +1 more source

Heart failure etiology and lipoprotein subfractions: Insight from the SMARTEX-HF study. [PDF]

open access: yesInt J Cardiol Heart Vasc
Karlsen T   +15 more
europepmc   +1 more source

Serum lipoproteins in patients with porphyria cutanea tarda

open access: green, 1999
ernández-Miranda C, de la Calle M, Gómez Izquierdo MT, Larumbe S, Enríquez de Salamanca R.
openalex   +1 more source

Unveiling Endotypes in Systemic Lupus Erythematosus Through Multi‐Omic Analysis: Insights into Cardiovascular and Renal Complications

open access: yesArthritis &Rheumatology, Accepted Article.
Background Systemic lupus erythematosus (SLE) shows clinical and molecular heterogeneity, and cardiovascular (CV) complications and lupus nephritis (LN) remain leading causes of morbidity and mortality. This study investigated whether omic profiling can reveal molecular endotypes linked to these outcomes.
Tomás Cerdó   +84 more
wiley   +1 more source

5‐Methylcytosine Analysis of miRNAs in Minimal Change Disease

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Minimal change disease (MCD) is a glomerular disorder, which is the most common cause of nephrotic syndrome in children. Additionally, the prevalence of MCD in adults has been increasing in recent years. During protein synthesis, noncoding RNAs can be regulated through a variety of modifications, which helps preserve biological diversity and ...
Huiyi Zeng   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy