Results 51 to 60 of about 739,784 (386)
Bifurcation analysis of a free boundary model of plaque formation associated with the cholesterol ratio [PDF]
The low-density lipoprotein (LDL)/high-density lipoprotein (HDL)-cholesterol ratio has been shown a high correlation with the cardiovascular risk assessment. Is it possible to quantify the correlation mathematically? In this paper, we develop a bifurcation analysis for a mathematical model of the plaque formation with a free boundary in the early stage
arxiv
Biological, clinical and population relevance of 95 loci for blood lipids. [PDF]
Plasma concentrations of total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol and triglycerides are among the most important risk factors for coronary artery disease (CAD) and are targets for therapeutic ...
Aulchenko, Yurii S+99 more
core
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna+4 more
wiley +1 more source
Apolipoprotein A-I was purified from human high density lipoprotein and complexed with polyunsaturated phosphatidylcholine (PC) in deoxycholate (Lipostabil); the bile salt was removed subsequently by dialysis.
J Koizumi+4 more
doaj
Apolipoprotein Mimetic Peptides: Potential New Therapies for Cardiovascular Diseases
Since the seminal breakthrough of treating diabetic patients with insulin in the 1920s, there has been great interest in developing other proteins and their peptide mimetics as therapies for a wide variety of other medical disorders. Currently, there are
Anna Wolska+4 more
doaj +1 more source
Oxysterols in Vascular Cells and Role in Atherosclerosis [PDF]
Atherosclerosis is a major cardiovascular complication of diseases associated with elevated oxidative stress such as type 2 diabetes and metabolic syndrome. In these situations, low density lipoproteins (LDL) undergo oxidation. Oxidized LDL display proatherogenic activities through multiple and complex mechanisms which lead to dysfunctions of vascular ...
arxiv +1 more source
Lipoprotein particles in patients with pediatric Cushing disease and possible cardiovascular risks. [PDF]
BackgroundCardiovascular (CV) complications are the most significant cause of mortality in adults with Cushing disease (CD); little is known about CV risk factors in children with CD.
Belyavskaya, Elena+10 more
core
The role of circular RNAs in regulating cytokine signaling in cancer
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi+4 more
wiley +1 more source
Using artificial triglyceride emulsions, we have demonstrated the presence of non-equilibrating pools of apolipoproteins C-II and C-III in human plasma lipoproteins.
L Tornoci+5 more
doaj
Apolipoprotein M (apoM) is a 26-kDa protein that is mainly associated with high-density lipoprotein (HDL) in human plasma, with a small proportion present in triglyceride-rich lipoproteins (TGRLP) and low-density lipoproteins (LDL).
Luo, Guanghua+3 more
core +3 more sources