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Lipoproteins and Atherosclerosis [PDF]
Author(s): Gofman, John W.; Lindgren, Frank T.; Jones, Hardin B.; Lyon, Thomas P.; Strisower, Beverly.
John W. Gofman +4 more
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IMMUNOCHEMICAL STUDIES ON HUMAN PLASMA LIPOPROTEINS [PDF]
Some years ago, a series of human serum lipoproteins, distinguishable by their hydrated densities and lipid-protein ratios were recognized and isolated by ultracentrifugal techniques (1).
Frederick Aladjem +2 more
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The relationship between the level of Lр(а) and the prevalence of atherosclerosis among young patients [PDF]
Background. Hyperlipoproteinemia (a) is an independent and cause risk factor for atherosclerotic cardiovascular diseases (ASCVD). The correlation between lipoprotein (a) Lp(a) and inflammation in the vessel wall was actively studied during the past few ...
Elena A. Klesareva +8 more
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AbstractLipoprotein(a) [Lp(a)] is an atherogenic lipoprotein with a strong genetic regulation. Up to 90% of the concentrations are explained by a single gene, theLPAgene. The concentrations show a several-hundred-fold interindividual variability ranging from less than 0.1 mg/dL to more than 300 mg/dL. Lp(a) plasma concentrations above 30 mg/dL and even
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The Anti-Thrombotic Effects of PCSK9 Inhibitors
Atherosclerosis is the primary process that underlies cardiovascular disease. The connection between LDL cholesterol and the formation of atherosclerotic plaques is established by solid evidence.
Martin Jozef Péč +10 more
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Lipoprotein (a): Recent Updates on a Unique Lipoprotein [PDF]
Genetic, epidemiological, and translational data indicate that Lipoprotein (a) [Lp(a)] is likely in the causal pathway for atherosclerotic cardiovascular diseases as well as calcification of the aortic valves.Lp(a) is structurally similar to low-density lipoprotein, but in addition to apolipoprotein B-100, it has a glycoprotein apolipoprotein(a) [apo(a)
Salim S. Virani +4 more
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Lipoprotein a: An emerging risk identifier and evolving clinical target
Pathophysiology, epidemiology and genetics data support the causal role of Lipoprotein a, Lp(a), in cardiovascular disease, and in aortic valve calcification and stenosis.
Konstantinos Tsarouhas* +3 more
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Background: Patients with acute coronary syndrome (ACS) still have a high risk of recurrence of major adverse cardiovascular and cerebrovascular events (MACCE).
Cai-Yan Cui +6 more
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Elevated lipoprotein A in acute on chronic CTEPH with cardiogenic shock: a case report
The natural history of most thrombi undergoes total or near total resolution, but the thrombi in chronic thromboembolic pulmonary hypertension (CTEPH) do not resolve completely and subsequently increase the pulmonary vascular resistance.
Kyaw Kyaw +4 more
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Effect of eight weeks High Intensity Interval Training (HIIT) on some atherogenic factors [PDF]
Background and aims: Atherosclerosis is the most important reason for disability and mortality in Iran and around the world, which is mainly due to improper and sedentary lifestyle. The aim of this study was to investigate the effects of eight weeks high
Mohsen Jafari +2 more
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