Results 101 to 110 of about 440,409 (317)
Background Higher lipoprotein(a) and oxidized phospholipid concentrations are associated with increased risk for coronary artery disease and valvular heart disease.
James L. Januzzi+8 more
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Lipoprotein(a) in chronic renal failure [PDF]
Cardiovascular diseases are the leading cause of mortality in patients with chronic renal failure. Among the parameters contributing to cardiovascular disease development is the elevated serum concentration of lipoprotein(a) diagnosed in these patients ...
Čabarkapa Velibor+5 more
doaj
Recent Advances in mRNA Delivery Systems for Cancer Therapy
This review systematically investigates the applications of mRNA therapy in cancer treatment, with particular emphasis on nonviral delivery systems, targeting strategies, stimulus‐responsive systems, and local delivery methods. Concluding with a meticulous evaluation, the review sheds light on the prevailing challenges while illuminating promising ...
Zheng Zhang+9 more
wiley +1 more source
Association between Lp(a) and T2D: a Mendelian randomization study
Introduction Blood lipoprotein(a) (Lp(a)) levels have been observed to be inversely correlated with type 2 diabetes (T2D). In this Mendelian randomization (MR) study, the causal impact of genetically predicted Lp(a) on T2D was assessed.
Marcin Goławski+5 more
doaj +1 more source
THE α2 LIPOPROTEINS OF HUMAN SERUM. CORRELATION OF ULTRACENTRIFUGAL AND ELECTROPHORETIC PROPERTIES [PDF]
Henry G. Kunkel, Rodes Trautman
openalex +1 more source
Lipoprotein(a): The Renaissance of an Enigmatic Lipoprotein [PDF]
openaire +4 more sources
Lp(a) is a genetically determined, heritable, independent and causal risk factor for ASCVD. About 1 in 5 people worldwide have elevated Lp(a) (>50 mg/dL or >125 nmol/L) whereas in Indians it is 25 %. Epidemiological, genome-wide association and mendelian randomization studies have demonstrated an association between elevated Lp(a) levels and increased ...
openaire +3 more sources
The TALENTs randomized controlled trial evaluates the potential of nucleotides supplementation as an anti‐aging intervention in older adults. After 19 weeks, nucleotides supplementation significantly reduces DNA methylation age, suggesting a delay in epigenetic aging, and improves insulin sensitivity without severe adverse events.
Shuyue Wang+9 more
wiley +1 more source
Separation of lipoproteins by traditional sequential salt density floatation is a prolonged process (∼72 h) with variable recovery, whereas iodixanol-based, self-generating density gradients provide a rapid (∼4 h) alternative.
Michael S. Yee+6 more
doaj
Irisin is a crucial plasma biomarker and promising therapeutic target that reflects disease severity, pulmonary vascular remodeling status and clinical outcome in patients with pulmonary arterial hypertension (PAH). As a novel protective factor, irisin is downregulated in PAH. By ubiquitination, irisin promotes Enolase 1 degradation and suppresses cell
Na Sun+15 more
wiley +1 more source